Ep. 631 The Metabolic Health Masterclass | Menopause, Perimenopause, Metabolic Health

Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Today, we have a metabolic health masterclass, featuring Dr. Robert Lustig, Ben Azadi, Dr. Ben Bikman, Mark Sisson, and Dr. Nick Norwitz. 

In today’s masterclass, we explore why metabolic dysfunction is not simply a calories-in, calories-out issue or a failure of willpower, how insulin and leptin influence appetite and behavior, how early signs of insulin resistance can appear years before a diabetes diagnosis, and the important relationship between muscle, glucose regulation, and insulin sensitivity. We also discuss how movement supports fat burning without sacrificing muscle, why chronic cardio may not produce the results many people expect, and how emerging technology could provide a far more personalized approach to metabolic care.

Stay tuned for today’s informative discussion, where our panel of experts shares their valuable perspectives on metabolic health.

IN THIS EPISODE, YOU WILL LEARN:

  • Leptin resistance and how it can drive the overeating and inactivity commonly associated with obesity

  • How elevated insulin blocks the effects of leptin

  • Why it’s essential to pay attention to fasting insulin rather than waiting for blood glucose to rise 

  • Ben Azadi highlights metabolic health markers that can provide information beyond fasting glucose.

  • How our muscles help to regulate glucose and support insulin sensitivity

  • The importance of building and preserving muscle to support insulin sensitivity as we age, and how even a brief period of inactivity can reduce insulin sensitivity

  • Mark Sisson explains why running may not be the most effective fat loss strategy 

  • How walking can increase your fat-burning capacity while also helping to preserve your muscles

  • Dr. Nick Norwitz explains how type 2 diabetes can involve different underlying pathologies, and how CGM data and machine learning can eventually help to identify specific subphenotypes

Connect with Cynthia Thurlow  

Connect with Dr. Robert Lustig

Website 

On Facebook, Instagram, and Twitter 

Connect with Ben Azadi

Website

On Instagram, Facebook, LinkedIn, YouTube, TikTok

Get a copy of Ben Azadi’s latest book, Metabolic Freedom.

Connect with Dr. Ben Bikman

Website

On social media: @benbikmanphd

Connect with Mark Sisson  

Mark’s book, Born To Walk 

Peluva Shoes

Connect with Nick Norwitz

On YouTube, X, and Instagram

His Substack

Previous Episodes:

Ep. 161 Robert Lustig & Cynthia Thurlow Discussing The Nutritional Battlefield & Debunking Chronic Diseases

Ep. 465 Metabolic Health 101: Fat Loss, Toxins, and Seed Oils with Dr. Ben Azadi

Ep. 316 The Impact of Age, Gender and Lifestyle on Metabolic Health with Dr. Ben Bikman

Ep. 422 Walking for Health: The Underrated Exercise You Need with Mark Sisson

Ep. 525 We’ve Been Misled About Metabolic Health – The Shocking Truth About Cholesterol, GLP-1 & Aging with Dr. Nick Norwitz


More description

Today, we have a metabolic health masterclass, featuring Dr. Robert Lustig, Ben Azadi, Dr. Ben Bikman, Mark Sisson, and Dr. Nick Norwitz. 

In today’s masterclass, we explore why metabolic dysfunction is not simply a calories-in, calories-out issue or a failure of willpower, how insulin and leptin influence appetite and behavior, how early signs of insulin resistance can appear years before a diabetes diagnosis, and the important relationship between muscle, glucose regulation, and insulin sensitivity. We also discuss how movement supports fat burning without sacrificing muscle, why chronic cardio may not produce the results many people expect, and how emerging technology could provide a far more personalized approach to metabolic care.

Stay tuned for today’s informative discussion, where our panel of experts shares their valuable perspectives on metabolic health.

IN THIS EPISODE, YOU WILL LEARN:

  • Leptin resistance and how it can drive the overeating and inactivity commonly associated with obesity

  • How elevated insulin blocks the effects of leptin

  • Why it’s essential to pay attention to fasting insulin rather than waiting for blood glucose to rise 

  • Ben Azadi highlights metabolic health markers that can provide information beyond fasting glucose.

  • How our muscles help to regulate glucose and support insulin sensitivity

  • The importance of building and preserving muscle to support insulin sensitivity as we age, and how even a brief period of inactivity can reduce insulin sensitivity

  • Mark Sisson explains why running may not be the most effective fat loss strategy 

  • How walking can increase your fat-burning capacity while also helping to preserve your muscles

  • Dr. Nick Norwitz explains how type 2 diabetes can involve different underlying pathologies, and how CGM data and machine learning can eventually help to identify specific subphenotypes

Connect with Cynthia Thurlow  

Connect with Dr. Robert Lustig

Website 

On Facebook, Instagram, and Twitter 

Connect with Ben Azadi

Website

On Instagram, Facebook, LinkedIn, YouTube, TikTok

Get a copy of Ben Azadi’s latest book, Metabolic Freedom.

Connect with Dr. Ben Bikman

Website

On social media: @benbikmanphd

Connect with Mark Sisson  

Mark’s book, Born To Walk 

Peluva Shoes

Connect with Nick Norwitz

On YouTube, X, and Instagram

His Substack

Previous Episodes:

Ep. 161 Robert Lustig & Cynthia Thurlow Discussing The Nutritional Battlefield & Debunking Chronic Diseases

Ep. 465 Metabolic Health 101: Fat Loss, Toxins, and Seed Oils with Dr. Ben Azadi

Ep. 316 The Impact of Age, Gender and Lifestyle on Metabolic Health with Dr. Ben Bikman

Ep. 422 Walking for Health: The Underrated Exercise You Need with Mark Sisson

Ep. 525 We’ve Been Misled About Metabolic Health – The Shocking Truth About Cholesterol, GLP-1 & Aging with Dr. Nick Norwitz


2026-08-19 63 min
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