Skin Aging Treatment and Skin Microbiome: What “Leaky Skin” Could Be Telling You About Inflammation, Hormones, and Healthy Aging | Kiran Krishnan

The Dr. Brighten Show

What if the condition of your skin was saying far more about your health than whether you need a new moisturizer? In this conversation, Dr. Jolene Brighten sits down with microbiologist Kiran Krishan to unpack a provocative idea: that skin barrier dysfunction may be linked not only to dryness, wrinkles, and hyperpigmentation, but also to systemic inflammation, hormone shifts, gut health, and even long-term disease risk.

This episode challenges the modern skincare mindset and asks a bigger question: are we trying to make skin look better while quietly making it less healthy?

This Episode Is Brought to You By

Dr. Brighten Essentials Myo-Inositol Plus— a research-backed formula designed to support hormone balance, metabolic health, and ovarian function. Featuring the clinically studied 40:1 ratio of myo-inositol to D-chiro-inositol, it helps promote healthy ovulation, improve insulin sensitivity, and support more regular cycles—making it a powerful daily tool for PCOS, fertility, and overall hormone support.

Exclusive for podcast listeners: use the code POD15 for 15% off your order. Shop now https://drbrightenessentials.com/products/myoinositol-plus

OneSkin 

Founded by an all-woman team of PhD-level scientists, OneSkin is revolutionizing aging with the OS-01™ peptide, the first ingredient proven to reverse skin’s biological age by targeting cellular senescence. The result? Skin that looks, feels, and acts younger. It’s never too early — or too late — to invest in your skin health.

Use code BRIGHTEN for 15% off your first purchase. Shop now https://oneskin.pxf.io/c/1950532/2885132/31050

Kiran Krishnan’s Instagram: https://www.instagram.com/kiranbiome/

👩🏻‍⚕️Follow Dr. Jolene Brighten:

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🌟 Grab my free hormone friendly recipes here! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drbrighten.com/hormonekit/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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More description

What if the condition of your skin was saying far more about your health than whether you need a new moisturizer? In this conversation, Dr. Jolene Brighten sits down with microbiologist Kiran Krishan to unpack a provocative idea: that skin barrier dysfunction may be linked not only to dryness, wrinkles, and hyperpigmentation, but also to systemic inflammation, hormone shifts, gut health, and even long-term disease risk.

This episode challenges the modern skincare mindset and asks a bigger question: are we trying to make skin look better while quietly making it less healthy?

This Episode Is Brought to You By

Dr. Brighten Essentials Myo-Inositol Plus— a research-backed formula designed to support hormone balance, metabolic health, and ovarian function. Featuring the clinically studied 40:1 ratio of myo-inositol to D-chiro-inositol, it helps promote healthy ovulation, improve insulin sensitivity, and support more regular cycles—making it a powerful daily tool for PCOS, fertility, and overall hormone support.

Exclusive for podcast listeners: use the code POD15 for 15% off your order. Shop now https://drbrightenessentials.com/products/myoinositol-plus

OneSkin 

Founded by an all-woman team of PhD-level scientists, OneSkin is revolutionizing aging with the OS-01™ peptide, the first ingredient proven to reverse skin’s biological age by targeting cellular senescence. The result? Skin that looks, feels, and acts younger. It’s never too early — or too late — to invest in your skin health.

Use code BRIGHTEN for 15% off your first purchase. Shop now https://oneskin.pxf.io/c/1950532/2885132/31050

Kiran Krishnan’s Instagram: https://www.instagram.com/kiranbiome/

👩🏻‍⚕️Follow Dr. Jolene Brighten:

💻 Website:⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.drbrighten.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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🎥 TikTok: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.tiktok.com/@drjolenebrighten⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

🧵Threads: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.threads.net/@drjolenebrighten⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

🌟 Grab my free hormone friendly recipes here! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drbrighten.com/hormonekit/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

🎧 Subscribe to the Podcast:

Apple: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://podcasts.apple.com/us/podcast/the-dr-brighten-show/id1786362161⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

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👉 If you found this episode valuable, drop a comment below to tell us what you loved most, and share it with a friend! Let’s spread the knowledge. 💬

Learn more about your ad choices. Visit megaphone.fm/adchoices

2026-04-07 47 min
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