The Cancer Vaccine That Could Save Moderna

The Journal.

For years, Moderna was a one-hit wonder, a company that bet everything on mRNA, struck gold with a COVID vaccine and then watched its stock crater as the pandemic faded. Now, the company may have found a way to fight skin cancer. An experimental mRNA-based vaccine succeeded in preventing melanoma from returning in high-risk patients, sending drug industry stocks soaring. WSJ’s Xavier Martinez traces Moderna’s wild ride from scrappy startup to the frontier of cancer treatment. Ryan Knutson hosts.


Further Listening:

- The FDA Commissioner on Vaccines and Public Trust

- The Creator of the Record-Setting Covid Vaccine

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Learn more about your ad choices. Visit megaphone.fm/adchoices

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For years, Moderna was a one-hit wonder, a company that bet everything on mRNA, struck gold with a COVID vaccine and then watched its stock crater as the pandemic faded. Now, the company may have found a way to fight skin cancer. An experimental mRNA-based vaccine succeeded in preventing melanoma from returning in high-risk patients, sending drug industry stocks soaring. WSJ’s Xavier Martinez traces Moderna’s wild ride from scrappy startup to the frontier of cancer treatment. Ryan Knutson hosts.


Further Listening:

- The FDA Commissioner on Vaccines and Public Trust

- The Creator of the Record-Setting Covid Vaccine

Sign up for WSJ’s free What’s News newsletter.

Learn more about your ad choices. Visit megaphone.fm/adchoices

2026-08-28 25 min
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