Fertility Q&A: Miscarriage, Low AMH, PCOS & More

Dr. Natalie Crawford, board-certified OB-GYN and REI, answers your fertility questions.

1. I’m 35, had a healthy pregnancy in 2022 followed by three miscarriages, and just found out I have 19% Turner mosaicism on karyotype. If I were your patient, would you recommend moving to IVF with PGT, or continue trying naturally?
   

2. I’m 32 with an LH/FSH ratio of 2.6 and an AMH of 2.7. The labs were drawn around suspected ovulation. Does this ratio suggest possible PCOS, or could this be a normal mid-cycle finding?
   

3. I’m 33 and have been trying to conceive for five months. My AMH just came back at 0.057, but the rest of my labs look normal. What would your next steps be, and what are the most common causes of very low AMH at my age?
   

4. My fiancé uses CBD gummies with trace amounts of THC for chronic pain. We know marijuana can impact fertility, but do CBD products with small amounts of THC meaningfully affect sperm health or fertility outcomes?
   

5. My partner and I are a same-sex female couple (ages 30 and 32) using donor sperm. We’ve had two unsuccessful IUIs, and I’m about to start a third with letrozole. My workup is normal, but I suspect possible endometriosis. If that’s the case, should we be considering additional evaluation or changing our treatment approach?

   
   

Pre-order Dr. Crawford's debut book, The Fertility Formula, now! https://www.nataliecrawfordmd.com/book

Want your questions answered on the next episode? ⁠Ask them here! https://www.nataliecrawfordmd.com/qa-submissions

Learn more about your ad choices. Visit megaphone.fm/adchoices