Why Matt Kaeberlein Says Most Longevity Advice Is Wrong

The Neuro Experience

Dr. Matt Kaeberlein is one of the world’s most respected scientists in the field of aging biology. In this episode, we unpack the real science of longevity — from mTOR inhibition and rapamycin to calorie restriction, biomarkers of aging, and what most people get wrong about lifespan vs healthspan. We go beyond the hype to ask: What actually works? What’s still theoretical? And where is the frontier of human aging research heading? Topics we cover: The biology of aging: mTOR, autophagy, senescence Rapamycin in humans: What we know and don’t Why extending healthspan matters more than living longer Matt’s views on supplements, diet, and biomarkers The most misunderstood concepts in anti-aging Referenced studies include: Dog Aging Project Interventions Testing Program Rapamycin human trial data *** I’m Louisa Nicola — clinical neuophysiologist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_

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Dr. Matt Kaeberlein is one of the world’s most respected scientists in the field of aging biology. In this episode, we unpack the real science of longevity — from mTOR inhibition and rapamycin to calorie restriction, biomarkers of aging, and what most people get wrong about lifespan vs healthspan. We go beyond the hype to ask: What actually works? What’s still theoretical? And where is the frontier of human aging research heading? Topics we cover: The biology of aging: mTOR, autophagy, senescence Rapamycin in humans: What we know and don’t Why extending healthspan matters more than living longer Matt’s views on supplements, diet, and biomarkers The most misunderstood concepts in anti-aging Referenced studies include: Dog Aging Project Interventions Testing Program Rapamycin human trial data *** I’m Louisa Nicola — clinical neuophysiologist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_

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2025-07-01 53 min
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