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Science Friday

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Covering the outer reaches of space to the tiniest microbes in our bodies, Science Friday is the source for entertaining and educational stories about science, technology, and other cool stuff.

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Researchers built the largest 3D map of our universe yet. What they found supports the idea that dark energy could have evolved over time.

One of the mysteries of the universe is why it expands at the rate that it does. Back in 1998, two teams of researchers observed that not only was the universe expanding, but that the rate of expansion was increasing. That observation was the basis for a concept now known as dark energy. In the years since, cosmologists have been trying to get a handle on better measurements of that effect, and hoping to figure out what dark energy actually might be.

This week, researchers on a project called DESI, the Dark Energy Spectroscopic Instrument, released results based on their first three years of data at an international physics conference. They found that it appears possible that dark energy—whatever it is—has changed over the lifetime of the universe. In other words, the so-called cosmological constant may not, in fact, be a constant. The data is not quite statistically significant yet, so researchers can’t definitively say that this is true, which leaves many questions about the nature of dark energy still unresolved.

Dr. Andrei Cuceu of the Lawrence Berkeley National Laboratory and Dr. Adam Riess of Johns Hopkins University and the Space Telescope Science Institute join Host Flora Lichtman to talk about the new research, and what remains to be discovered in dark energy.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374


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After nine months aboard the International Space Station, astronauts Butch Wilmore and Suni Williams have finally landed back on Earth. Also, a German physicist and homebrewer discovered brief, intense physical reactions that happen when you uncork a bubbly swing-top bottle.

NASA Astronauts Return To Earth After Extended Stay On The ISS

After 286 days aboard the International Space Station—278 days longer than their initial planned mission—NASA astronauts Butch Wilmore and Suni Williams landed safely back on Earth on Tuesday, off the coast of Florida. Their mission turned into a nine-month stay on the station after their Boeing Starliner capsule had issues with its thrusters and NASA deemed it unsafe to carry the astronauts back. SpaceX’s Dragon capsule instead ferried them to Earth earlier this week. And they had a splashdown surprise: A pod of curious dolphins greeted them after they landed.

Host Flora Lichtman is joined by Casey Crownhart, senior climate reporter at MIT Technology Review, to catch us up on that and other big science stories from this week, including why a company is trying to “refreeze” a massive glacier, why the 10 hottest years on record are the last 10, and how the London Zoo is trying to conserve a unique frog that incubates its young in its vocal sacs.

The Physics That Makes Swing-Top Bottles ‘Pop’

For a lot of us, uncorking a bottle is the sound of celebration. It’s also a sound that we may not think too much about—until we open our next bottle.

But Dr. Max Koch, a physicist at the University of Göttingen who does home brewing on the side, got to wondering what actually makes that popping sound. What’s happening inside that bottle, physics-wise? To find out more, he recorded the uncorking of an unsuccessful batch of his ginger beer using microphones and a high-speed camera, and analyzed the bubbly results with a physicist’s rigor. His team’s findings were published in the journal Physics of Fluids.

Dr. Koch sits down with Host Flora Lichtman to talk about the brief but intense changes to temperature, sound, and speed that happen when you uncork a swing-top glass bottle.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374


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The framework of Adverse Childhood Experiences started with an unexpected finding over 30 years ago. How is our approach changing? 

We know that experiences from our childhood, both good and bad, shape who we become as adults. But, understanding what kinds of early experiences have staying power into adulthood and the wide range of impacts they can have is an emerging science.

In the 1980s, Dr. Vincent Felitti ran a weight loss clinic in San Diego, California. He noticed that some patients who regained weight were more likely to have experienced sexual abuse in childhood.This eventually led him to conduct research on a larger scale to better understand the correlation between what he and his colleagues dubbed adverse childhood experiences, or ACES, and mental and physical health challenges later in life.

This same 10-question survey Dr. Felitti gave participants in the 1990s is still used by researchers and clinicians to assess childhood trauma. But recently, some psychology experts have begun to question how accurately the ACES framework identifies trauma in diverse populations, since it was originally developed for a mostly white and affluent study population.

Host Flora Lichtman talks with Preeti Simran Sethi, science writer and Rosalyn Carter Mental Health Journalism fellow, about her reporting for Science Friday about adverse childhood experiences.

Also, to see more butterfly stories from our listeners, visit our story from last week. 

Transcripts for each segment will be available after the show airs on sciencefriday.com.

Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374


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Former NIH director Dr. Harold Varmus speaks out about what recent budget cuts and policy changes could mean for science.

One of the areas targeted by President Trump’s administration for cuts has been the National Institutes of Health (NIH). Cost-cutting actions have included the layoffs of some 1,200 NIH employees, the termination of research grants, a pause in the “study sections” that evaluate and award grant funding, and a cap on indirect costs included in research grants. Some of those moves have been paused following court cases. 

Dr. Harold Varmus, a former director of the National Institutes of Health, joins Host Ira Flatow to talk about the actions, and the impact he fears they could have on the future of biomedical research in the United States.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374


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Fungal networks in the ground ferry crucial nutrients to plants. But how do brainless organisms form complex supply chain networks? Also, in this year’s baseball spring training, the new Automated Ball-Strike System is helping settle challenges to home plate pitch calls.

Scientists Observe Fungi Creating Complex Supply Chains

As the leaves start to pop out, it’s natural to look up and admire the trees. But actually, there’s a lot of action happening underneath your feet. Beneath you is a complex network of fungal trade routes carrying essential nutrients to the roots of plants, mined from the soil by fungus. It’s a subterranean supply chain.

But how exactly do these complex networks form? How does the fungus decide where to ship which resources, or where to build roads? Basically, how does a brainless thread make decisions?

Host Flora Lichtman is joined by Dr. Toby Kiers, an author on a recent study of those networks, and professor of evolutionary biology at Vrije University in Amsterdam. She’s also the executive director of the Society for the Protection of Underground Networks (SPUN).

A Rookie Robot Umpire Takes The Field

Baseball fans are eagerly awaiting opening day. And while spring training is a time for teams to test out new players and strategies, it’s also a time for Major League Baseball to trial new rules and procedures. One of the things that the league has been testing this year is a robotic system to call balls and strikes.

The Automated Ball-Strike System, which is based on the same technology used for line judging in tennis, isn’t calling every pitch, but is used to back up a challenge system at the plate. The tech is already in use in Triple-A games, and could make it to the major leagues in the years ahead. Baseball writer Davy Andrews joins Host Ira Flatow to talk about the technology, and how it could subtly change the rules of the game.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374


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Layoffs at the agency, which releases weather forecasts and monitors extreme weather, could have serious implications. Also, funds for climate and sustainability-focused farming projects have been indefinitely frozen, even though the USDA has already signed contracts.

10% Of NOAA Staff Laid Off, With More Cuts Possible

The National Oceanic and Atmospheric Administration, better known as NOAA, impacts and provides services for Americans every day. The agency releases daily weather forecasts and monitors extreme weather, and it also conducts research into global weather and climate change.

Along with many other federal science agencies, NOAA is being subjected to layoffs in the name of cost-cutting: 10% of the agency’s workforce has been laid off, with 1,000 more cuts potentially to come. According to Dr. Timothy Gallaudet, acting NOAA administrator during Trump’s first term, this is likely to lead to declines in quality of service and access to information about weather events.

Host Flora Lichtman speaks to Umair Irfan, science correspondent at Vox, who has been covering the turmoil at NOAA. They also discuss other science stories of the week, including the death of prolific blood donor James Harrison.

Frozen Climate And Conservation Funds Leave Farmers In Limbo

Around the country, farmers are planning and planting this year’s crops. It can be uncertain work, made even more tenuous by some of the Trump administration’s changes to climate and conservation policies.

The administration has frozen billions of dollars in grants to farmers for sustainable agriculture, conservation, and “climate smart” projects. In some cases, farmers had already signed contracts with the government and begun work on these projects.

While some funding from the Inflation Reduction Act was recently released, many farmers across the country are still in limbo.

Host Flora Lichtman talks with Patrick Brown, a farmer in Warren County, North Carolina; and Dr. Kitty O’Neil, an agricultural climate resiliency specialist at Cornell University’s Cooperative Extension about the future of farming in a changing climate.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374


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It’s March 14, or Pi Day, that day of the year where we celebrate the ratio that makes a circle a circle. The Greek letter that represents it is such a part of our culture that it merits our irrational attention.

Joining Host Ira Flatow to help slice into our pi’s is Dr. Steven Strogatz, professor of math at Cornell University and co-host of Quanta Magazine’s podcast “The Joy Of Why.” They talk about how pi was “discovered,” the ways it’s figuring into recent science, and how AI is changing the field of mathematics.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374


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When you imagine prehistoric life, it’s likely that the first thing that comes to mind are dinosaurs: long-necked Apatosauruses, flying Pterosaurs, big toothy Tyrannosaurs. But what don’t get as much attention are the prehistoric plants that lived alongside them.

Plants, shrubs, and trees played a key part in the food chains of dinosaurs, and many dinosaurs evolved to match the plant life available to them. The Apatosaurus’ long neck, for example, developed to reach leaves high up in prehistoric trees.

Joining Host Flora Lichtman to defend the importance of prehistoric plants is Riley Black, author of the new book When the Earth Was Green: Plants, Animals and Evolution’s Greatest Romance. She’s based in Salt Lake City, Utah.

Read an excerpt from When the Earth Was Green at sciencefriday.com.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374


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An international team of researchers used drones to study narwhals and learn more about their behavior. And, a total lunar eclipse will be visible across most of North and South America in the early morning hours of March 14.

New Footage Shows How Narwhals Use Tusks To Hunt And Play

We’re taking a polar plunge into the science of sea unicorns, also known as narwhals!

Narwhals are mysterious arctic whales with long, twirly tusks protruding from their foreheads, like a creature out of a fairy tale. And it turns out that we don’t know too much about them, partly because they live so far north in the remote Arctic.

An international team of researchers used drones to observe narwhals in the wild and learned new things about their behavior, including how they use their tusks to hunt and play.

Host Flora Lichtman gets on the horn with Dr. Gregory O’Corry-Crowe, research professor and biologist at Florida Atlantic University, who was an author on the new narwhal study, published last month in Frontiers in Marine Science.

How To See The ‘Blood Moon’ Lunar Eclipse This Week

Early on Friday, March 14 (or super late on Thursday, March 13, depending on your time zone) people across the U.S. will be able to watch a total lunar eclipse, if skies are clear. The partial eclipse will begin at 1:09 a.m. Eastern time on Friday the 14th, with totality lasting from 2:26 to 3:31 a.m. Eastern.

Astronomer Dean Regas joins Host Flora Lichtman to tell us what to expect, and share some tips for comfortable lunar eclipse viewing.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

 

 

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Extract Knowledge
Published 2025-03-11

Where Have All The Butterflies Gone?

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A sweeping new study on one of the most beloved insects, maybe the only truly beloved insect—the butterfly—details its rapid population decline in the United States. The new research, published in the journal Science widens the butterfly net and looks at how more than 500 species have fared over the past 20 years.

Researchers found that many populations are taking a nosedive. What’s causing the downswing, and is there anything we can do?

Host Flora Lichtman talks with two of the study authors, Dr. Elise Zipkin, Red Cedar distinguished professor of quantitative ecology and director of the ecology, evolution and behavior program at Michigan State University; and Dr. Nick Haddad, professor of integrative biology also at Michigan State University in East Lansing, Michigan.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374


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On the very first day of Donald Trump’s second term, he signed an executive order targeting foreign aid programs, especially the U.S. Agency for International Development (USAID).

Comprising less than 0.1% of the federal budget, USAID provides international humanitarian and development aid for poverty eradication, education, disease prevention, and medical programs. The Trump administration has cut off funding for these programs and most of the USAID staff was placed on leave or laid off.

Since January, hospitals and clinics in places like Thailand, Syria, and India have shuttered; clinical trials on HIV and maternal health have been canceled; and projects on polio, malaria, and tuberculosis prevention have been stopped.

Then, this week, the Supreme Court rejected a bid to keep some aid funds frozen. But what does that mean in practice for USAID’s global health initiatives?

Host Flora Lichtman talks about the global health implications of dismantling USAID with Dr. Atul Gawande, surgeon and former head of global health at USAID; and Dr. Salim Abdool Karim, epidemiologist and director of the Centre for the AIDS Programme of Research in South Africa.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374


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Scientists aren’t always encouraged to be politically active. But recent political interference by the Trump administration has many fired up. And, the Blue Ghost lunar lander, part of NASA’s CLPS initiative, completed the first fully successful commercial moon landing.

Protesters ‘Stand Up For Science’ At Rallies Across The Country

Scientists and defenders of science are gathering in cities across the U.S. today as part of Stand Up for Science rallies, events to protest recent political interference by the Trump administration in science funding. The main rally in Washington, D.C. features speakers including Bill Nye, Dr. Frances Collins and Dr. Atul Gawande, and will advocate for ending censorship, expanding scientific funding, and defending diversity, equity, and inclusion.

Host Flora Lichtman speaks to science reporter Anil Oza, a Sharon Begley Fellow at STAT and MIT, about the runup to Stand Up For Science, and what he’s heard from organizers and attendees. Then, Flora speaks with two listeners, D.C.-based planetary scientist Mike Wong and University of Louisville student Emily Reed, about why they’re fired up to attend local rallies. 

Touchdown For The Blue Ghost Lunar Lander

Last weekend, the Blue Ghost lander, built by the Texas-based company Firefly Aerospace, became the first commercial spacecraft to execute a fully successful landing on the surface of the moon. On board the lander were 10 NASA instruments flown as part of NASA’s Commercial Lunar Payload Services (CLPS) initiative. The lander will be in operation on the moon over the course of one lunar day (about 2 Earth weeks), before running out of battery power as the lunar night falls.

Kevin Scholtes, an engineer at Firefly Aerospace, and Dr. Nicky Fox, associate administrator for the NASA Science Mission Directorate, join Host Flora Lichtman to talk about building a commercial spacecraft, the role of private companies in spaceflight, and some of the science the mission aims to achieve.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374


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Last year, 9,000 deceased donor kidneys were discarded due to storage and time limitations. A kidney “life support” machine could change that. Also, the SS United States will join Florida’s 4,300 artificial reefs—human-made places for fish and other marine life to live. How do these reefs work?

The Effort To Save Thousands Of Donor Kidneys From Being Wasted

Sylvia Miles was diagnosed with lupus in 2006, a chronic autoimmune disease that causes the body’s immune system to attack healthy tissue—including her kidneys.

Miles, who lives in Indianapolis, was later diagnosed with advanced kidney disease, and was in need of a kidney transplant.

Kidney diseases are one of the leading causes of death in the United States with 37 million people living with chronic kidney disease. Together with advanced kidney disease—the later stage of CKD—it cost Medicare billions of dollars in recent years.

People like Miles, who need a kidney transplant, wait an average of five years—often on dialysis.

But despite the long waitlists and organ shortages, around 9,000 kidneys from deceased donors last year were discarded due to perceived issues with their viability. A new Indiana-based organization, 34 Lives, is working to limit that waste and rehabilitate the organs.

Read the rest of this article on sciencefriday.com.

Ocean Liner SS United States Will Become An Artificial Reef

This week, after a notable career, the SS United States, a 1950s ocean liner, took her sunset cruise. Like many retirees, the ship is heading south—from Philadelphia to Florida—where she’ll be reinventing herself. In this next chapter, the SS United States will have new passengers: fish and other marine creatures. The ship will be sunk to the bottom of the sea and turned into an artificial reef, joining more than 4,300 artificial reefs off the coast of Florida.

Other sunken ships have become artificial reefs in the past, which have helped boost marine life as well as scuba diving and fishing tourism. Host Flora Lichtman speaks with Scott Jackson, a regional specialized agent with the Florida Sea Grant and University of Florida IFAS extension, about the science behind artificial reefs, and what has been learned from decades of research.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374


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A journalist traveled to five continents to learn about the afterlife of our trash, and why most “recyclable” plastic actually isn’t.

Have you ever gotten to the end of, say, a jar of peanut butter and wondered if it should go in trash or recycling? If it’s worth rinsing out? And where will it actually end up?

Journalist Alexander Clapp had those same questions, and went to great lengths to answer them—visiting five continents to chronicle how our trash travels. Along the way, he discovered a multibillion dollar trash trade run by shady waste brokers, and a global industry powered by slimy spoons, crinkled plastic bags, and all the other stuff we throw away. It’s a putrid business that we’re a part of, and many of us know little about.

Host Flora Lichtman speaks with Clapp about the garbage business and his new book Waste Wars: The Wild Afterlife Of Your Trash.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374


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A study finds that Peto’s Paradox, which states that larger animals are no more likely to get cancer than smaller ones, may not hold up. Also, a nearly complete predator skull was found in the Egyptian desert. Its lineage indicates that it was a top carnivore of the age.

What Does An Animal’s Size Have To Do With Its Cancer Risk?

If you throw a huge party, there’s more of a chance of problems than if you host a quiet get-together for a couple of friends. The logic is simple: Having more people around means more opportunities for chaos. Similarly, it would seem to make sense that in animals, a bigger species with more cells might have a greater chance of something going wrong with one of those cells, including mutations leading to cancer.

Back in 1977, a British epidemiologist named Richard Peto observed that that didn’t seem to be true. Bigger animals didn’t seem to have a greater risk of cancer than smaller ones. That became known as Peto’s Paradox, and has been a topic of debate among cancer biologists ever since.

Research published this week in the Proceedings of the National Academy of Sciences takes a new look at Peto’s Paradox using an unusual set of data—death reports from zoos around the world. Dr. Sarah Amend of Johns Hopkins Medical School joins Host Flora Lichtman to explain why, in their findings, Peto’s Paradox doesn’t seem to hold up—and what studying animal cancer rates could teach scientists about improving human health.

Meet Bastetodon, A 30 Million-Year-Old Apex Predator

Once upon a time, some 30 million years ago, what is now Egypt’s Western Desert was a lush forest. Humans had not evolved yet, the nearest relatives being monkey-like creatures. And through those forests stalked Bastetodon syrtos, a newly described apex predator from an extinct lineage known as the Hyaenodonts—one of the top carnivores of the age.

Researchers recently discovered a nearly complete skull of the creature. They reported on the find in the Journal of Vertebrate Paleontology. Host Flora Lichtman talks with Shorouq Al-Ashqar of the Mansoura University Vertebrate Paleontology Center about the discovery, and the picture it helps paint of ancient life.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374


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Changes limiting programs, grants, and even the nature of studies are already underway at the NIH, NSF, FDA, CDC, and more.

On President Trump’s first day in office, he signed an executive order to end what he calls “illegal and immoral discrimination programs,” referencing diversity, equity, and inclusion (DEI) in the federal government. The repercussions of this are already being felt across science agencies.

Things are changing fast: Last week, a federal judge in Maryland temporarily blocked parts of the DEI purge from being carried out. At the same time, federal research agencies have already made changes. For example, the National Institutes of Health suddenly pulled a program that provides grants to PhD students from marginalized backgrounds, and has already canceled studies mid-project, like one on LGBTQ cancer patients. The National Science Foundation has begun reviewing active research science projects that may not comply with Trump’s executive orders. The Centers for Disease Control and Prevention took down resources for HIV prevention, LGBTQ+ health, contraception, and more—then partially restored them, as ordered by a judge. And the Food and Drug Administration pulled its guidance on the importance of having some diversity in clinical trials, like those to test drugs and medical devices.

So, what does banning diversity, equity, and inclusion efforts mean for medical research? And what does it mean for our health?

Host Flora Lichtman talks with Dr. Rachel Hardeman, director of the Center for Antiracism Research for Health Equity at the University of Minnesota in Minneapolis; and Dr. Melissa Simon, an ob-gyn at Northwestern Medicine, and director of the Center for Health Equity Transformation in Chicago.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374


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The acting head of the NIH reportedly pushed back against legal guidance to resume grant funding, leaving federal workers in the lurch. Also, though fungi make up a tiny part of the human microbiome, they play an important role in both the prevention and development of many diseases.

Cuts And Conflicting Directives Sow Confusion For NIH Workers

Just over a month after President Trump’s inauguration, federal science in the US is in a state of disarray. Executive orders to halt grant funding at the National Institutes of Health (NIH) have faced court challenges. Last week, a federal judge extended a restraining order on a proposal to cap NIH grant funding for indirect costs, costs that experts say are critical to their work. But according to new reporting, staff within the NIH have been left without clear guidance about moving forward with those grants, with the NIH’s acting director reportedly pushing back against legal guidance from the agency’s lawyers to restart distribution of the funding.

Host Flora Lichtman is joined by Katherine J. Wu, staff writer for The Atlantic, who reported on the turmoil at the NIH. They also talk about other science news of the week, including an update on the measles outbreak in Texas, how to see every planet in the solar system this week, and how scientists think runner Faith Kipeygon could be the first woman to break a four-minute mile.

You’ve Heard Of The Microbiome—Welcome To The Mycobiome

You’ve heard of the microbiome, the community of bacteria, viruses, archaea parasites, and fungi that live in our bodies. But that last member of the group, fungi, get a lot less attention than the others. And perhaps that’s unsurprising. After all, bacteria outnumber fungi 999 to 1 in our guts.

But now, scientists are beginning to piece together just how important fungi truly are. Disruption in the fungal balance can play a role in the development of Crohn’s disease, irritable bowel disease, celiac disease, colorectal cancer, some skin diseases, and more.

Host Flora Lichtman talks with Dr. Mahmoud Ghannoum, microbiologist and professor at Case Western Reserve University’s School of Medicine, who has dedicated his career to studying the fungi in our bodies, and coined the term mycobiome over a decade ago.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374


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Extract Knowledge

The bone and joint structures in mammal tails help them keep their balance. Could those benefits be adapted for robots? And, in her first children’s book, conservationist Bindi Irwin takes little readers on a journey through Australia Zoo.

In Search Of The Best Tail For Balance

If you have met a cat, you’ve probably at some point been amazed by how acrobatic they are. They’re able to reorient themselves effortlessly, even in midair. It turns out that a lot of that twistiness comes down to having a top-tier tail. While most reptile tails can swing only in one plane of movement, mammal tails have more joints, leading to better inertial control. That lets mammals tweak their balance better, much as holding a balance pole can help an acrobat navigate a tightrope.

In a recent study published in the Journal of the Royal Society Interface, researchers explored the biomechanics of different tails, and considered how a better tail could help build a better robot. Dr. Talia Moore, a roboticist at the University of Michigan, and Dr. Ceri Weber, a cellular and developmental biology postdoc at UC San Diego, join Host Flora Lichtman to talk tails.

Bindi Irwin Encourages Kids To Become ‘Wildlife Warriors’

Almost 30 years ago, conservationists Terri Irwin and the late Steve Irwin captured the world’s attention with their show “The Crocodile Hunter.” It introduced millions of people to Australia Zoo and the strange, often scary, sometimes cute, critters from Down Under.

Now, Terri and her children—Bindi and Robert—are at the helm of the zoo, which is the setting for Bindi’s new children’s book, You Are a Wildlife Warrior!: Saving Animals & the Planet. In it, Bindi takes little readers and her own daughter, Grace, on an adventure through the zoo.

Host Flora Lichtman talks with Bindi about her family’s legacy, how motherhood fuels her approach to conservation, and what it’s like to run a zoo.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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Pancreatic cancer is notoriously difficult to treat, and about 90% of diagnosed patients die from the disease. A team at Memorial Sloan Kettering has been working to improve those outcomes by developing a new mRNA vaccine for pancreatic cancer.

A few years ago, the team embarked on a small trial to test the vaccine’s safety. Sixteen patients with pancreatic cancer received it, and even though it was a small study, the results were promising: Half the participants had an immune response, and in those patients the cancer hadn’t relapsed after 18 months.

This week, the team released a new study in Nature following those same patients, and found six out of eight who responded to the vaccine in the first study did not have their cancer return more than three years later.

Joining host Flora Lichtman to talk about these results, and what they could mean for the future of cancer treatment, is study author and surgeon Dr. Vinod Balachandran, director of The Olayan Center for Cancer Vaccines at Memorial Sloan Kettering, based in New York City.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

 

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It’s been an unusually tough winter virus season. Rates of flu-like infections are higher than they’ve been in nearly 30 years. And for the first winter since the start of the COVID-19 pandemic, flu deaths have surpassed COVID deaths. Add to that a higher-than-average year for norovirus, a nasty type of stomach bug.

Then there’s the emerging threat of avian flu. While there is no evidence of human-to-human transmission of the virus, about 70 people in the US have contracted the virus from livestock since April 2024.

To make sense of the latest viral trends, Host Flora Lichtman talks with Dr. Katelyn Jetelina, epidemiologist and author of the newsletter “Your Local Epidemiologist”; and Dr. Erica Shenoy, chief of infection control at Mass General Brigham hospital.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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Last week, some 3,500 people from across scientific fields gathered in Boston for the annual meeting of the American Association for the Advancement of Science (AAAS). The organization’s CEO, Dr. Sudip Parikh, gave a rousing speech to attendees.

“Destruction for the ill-conceived notion of cutting costs didn’t put an American on the moon, and it didn’t wipe smallpox from the face of the Earth,” Parikh said in opening remarks.

He was referring, of course, to the huge funding cuts and mass firings happening across federal science and health agencies under the Trump administration. Over the last few weeks, news of these cuts has been frequent—along with the cancellation of grants that include certain prohibited words and the disappearance of data from agency websites.

So what’s happening, and how should the scientific community respond? Host Flora Lichtman sat down with Dr. Sudip Parikh to discuss the importance of this point in time for American science and technology, what cuts for “efficiency” are getting wrong, and what’s at stake in the next few weeks.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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Finding the original tomb of the royal is one of the most significant developments in Egyptian archeology in recent history. Also, a video of a gloriously creepy anglerfish inspired tears and poetry online. But why was this deep-sea dweller near the surface at all?

Royal Tomb Of Egyptian King Thutmose II Unearthed

A British-Egyptian team has made one of the most significant Egyptian archeological finds in recent history: the tomb of pharaoh King Thutmose II, who ruled sometime between 2000 and 1001 BCE. This is the first tomb of a pharaoh unearthed since Tutankhamun’s in 1922.

Thutmose II’s mummified remains were found two centuries ago, but they had been moved from his original tomb, the location of which remained a mystery until now. Part of the reason why his tomb’s location was such a mystery was that Thutmose II was buried in an area associated with the wives of Egyptian kings, about 1.5 miles west of Egypt’s famous Valley of the Kings.

Joining Host Flora Lichtman to talk about this and other science stories of the week is Maggie Koerth, science writer and editorial lead of CarbonPlan, based in Minneapolis, Minnesota.

Why The Internet Was Captivated By A Hideous Fish

Last week, a viral video likely floated to the top of your feed: a rare black seadevil anglerfish, which looks like a floating head with a frightening amount of teeth and two cloudy eyes, swimming in azure waters. The fish showed up near Spain’s Canary Islands, off the northwestern coast of Africa. It made the news because it was spotted near the surface, while anglerfish normally reside in the deep ocean.

So why was she paddling so close to the surface? Was she sick? How unusual is this? And also, why do they even look like that? We had questions.

Host Flora Lichtman talks with Dr. Kory Evans, assistant professor of biosciences at Rice University, to separate fact from fish-ction. He also explains new research he helped conduct about the evolutionary history of anglerfish, which could help explain why they look the way they do.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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We have lots of expressions to describe the pain of loss—heartache, a broken heart, a punch in the gut. These aren’t just figures of speech: While grief is an emotional experience, it’s also a physical one. Studies show that grief can change your physiology, most dramatically in the cardiovascular and immune systems.

One staggering finding? A heart attack is 21 times more likely to happen in the 24 hours after the death of a loved one. And after the death of a parent, risk of ischemic heart disease rises by 41%, and risk of stroke increases by 30%.

Dr. Mary-Frances O’Connor has dedicated her career to understanding the physiology behind grief and grieving. She joins Host Flora Lichtman to discuss what she’s learned over the years, and her new book The Grieving Body.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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Can Men and Women (Baboons) Really Just Be Friends?

In the romantic comedy “When Harry Met Sally,” the central premise, as Billy Crystal and Meg Ryan’s characters stay friends throughout the years, is, can men and women really just be friends?

In the movie, the answer is no, not really. Spoiler alert: They do get together in the end. But what if we take that concept and bring it to the animal kingdom, specifically to primates?

The Kinda baboon is known for its distinct social behaviors. Individuals form long-term, social bonds, and those relationships are seen, uniquely, between male and female baboons. Over nine years, researchers studied the Kinda baboon, a kinder, gentler species of baboon, to learn more about their social lives. Kindas are unique among baboons because they’re the least sexually dimorphic: males and females are close to the same size, making them a better analog for us humans.

So can male and female baboons really be just friends? Much like the movie, long friendships do happen between Kindas—but there also appears to be a benefit during mating season.

Joining Host Flora Lichtman to talk about her work with these baboons is Dr. Anna Weyher, founder of the Kasanka Baboon Project in Zambia. Weyher has studied Kinda baboons for over a decade.

The Best Bear Deterrent May Be Drones

What do you do when a bear keeps coming too close to people, and doesn’t take the hint to stay away? It’s a serious problem, because human-wildlife conflict can be dangerous for both the people and animals involved. Wildlife managers have for years used a collection of deterrents, including firecracker noises, rubber bullets, and trained dogs, to try to chase bears away from human habitations.

Writing in the journal Frontiers in Conservation Science, former Montana bear management specialist Wesley Sarmento claims that a high-tech approach may be more effective: drones. Sarmento joins Host Flora Lichtman to discuss his experiences with hazing stubborn bears.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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The North and South Poles, also known as Earth’s iceboxes, help cool the planet, store fresh water, influence weather patterns, and more. They’re also the fastest warming places on Earth.

A new book called Ends of The Earth: Journeys to the Polar Regions in Search of Life, the Cosmos, and Our Future illustrates the wonders of Antarctica and the Arctic—and the lengths scientists go to to study them before it’s too late.

Host Ira Flatow talks with author Dr. Neil Shubin, an evolutionary biologist at the University of Chicago, about some of the wonders found at the ends of the Earth, and the threats they’re facing.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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It’s the first FDA approval for a pain medication in 25 years. How does the drug work, and who is it for? Also, non-mixing layers of water and hydrocarbons thousands of miles deep could explain the icy planets’ strange magnetic fields.

The FDA Approves A New, Non-Opioid Painkiller

In January, the Food and Drug Administration approved a new pain medicine called Journavx (suzetrigine), made by Vertex Pharmaceuticals. It’s the first time in 25 years the agency has given the green light to a new painkiller. Notably, it’s not an opioid and, according to the company, it’s not addictive. Unlike opioids, which act directly on the brain, Journavx instead blocks nerve endings across the body that transmit pain.

Host Ira Flatow is joined by Dr. Sean Mackey, a professor of anaesthesiology and pain medicine at Stanford University and chief of the Division of Stanford Pain Medicine, to discuss how the new drug works, who should take it, and what its limitations are.

Might Uranus And Neptune Have Deep, Multi-Layer Oceans?

We’ve got a pretty good idea about what’s beneath the surface of our nearest planetary neighbors, like Mars. But as you get farther out into the solar system, our knowledge becomes scarce. For instance, what’s inside the so-called ice giants, Neptune and Uranus?

Recent research based on computer simulations of fluids hints that the planets could contain vast multi-layered oceans, as much as thousands of miles deep. A layer of water that is on top of—but doesn’t mix with—a deeper layer of hydrocarbons could help explain strange magnetic fields observed during the Voyager mission.

Dr. Burkhardt Militzer, a professor of earth and planetary sciences at UC Berkeley, wrote about this idea in the Proceedings of the National Academy of Sciences. He joins Host Ira Flatow to explain his theories.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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Most Powerful Neutrino Ever Is Detected In the Mediterranean

Neutrinos are sometimes called “ghost particles,” because they are nearly weightless, rarely interact with any other matter, and have very little electric charge.

Now, scientists have discovered a neutrino with a recording-breaking level of energy, which could bring us closer to understanding physics underpinning the creation of the universe.

Host Ira Flatow is joined by Sophie Bushwick, senior news editor at New Scientist, to talk more about the latest in neutrino research and other top science news of the week, including supersonic spaceflight without a sonic boom; an asteroid headed for Earth; and why loggerhead turtles are dancing.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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In "Common Side Effects," the starring scientist finds a mushroom that can heal any ailment. But powerful people will do anything to stop him from cultivating it. And, a combination of environmental factors and the way our bodies function play a role in how we perceive the smell of snow.

In ‘Common Side Effects,’ A Clash Over An All-Healing Mushroom

In the new Adult Swim show “Common Side Effects,” an eccentric scientist has a secret: He’s discovered a strange mushroom that can cure any illness or injury, and he wants to get it to people in need. The only problem is that a pharmaceutical company doesn’t want that secret to get out and will do anything to make sure he’s stopped.

Joining Host Flora Lichtman to break down this fungal drama, and the science that inspired it, are the show’s creators, Steve Hely, who previously wrote for “30 Rock” and “Veep;” and Joe Bennett, creator of the animated sci-fi show “Scavengers Reign” on Max.

Why Snow Has That Crisp, Clean Smell

If you know snow, you might know that it has a particular smell to it. It has to do with where you are and how cold it is. It may even involve the memory parts of your brain.

Producer Rasha Aridi talks with Host Flora Lichtman about the science behind that snowy smell, featuring Dr. Johan Lundström, snow aficionado and professor of psychology at the Karolinska Institute in Stockholm, Sweden.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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Every year, billions of dollars are funneled into Alzheimer’s research. And yet, so far, there’s no treatment that’s been able to reverse the disease, or even meaningfully slow the cognitive decline of patients.

Part of the reason is that the disease is complex, and brain disorders are notoriously difficult to understand.

But in a new book, an investigative science reporter makes the case that there’s another reason progress toward Alzheimer’s treatments has stalled: scientific fraud.

Host Flora Lichtman talks with Charles Piller, investigative journalist at Science and author of the book Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer’s.

Read an excerpt of Doctored at sciencefriday.com.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

 

 

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In late September, firefighters in flame-resistant Nomex were strung out along a fireline. It ran midslope through a pine and hardwood forest above the Klamath River and the small northern California town of Orleans.

Several members of the Karuk tribe were laying down strands of fire with drip torches.

Aja Conrad, who runs the tribal natural resource department’s environmental education field institute, was the firing boss trainee. She kept a close eye as the strips burned together and smoke filled the air.

“Can you just keep an eye on that and maybe not put too much fire below it?” she told one of her burners.

“Copy that.”

Read the rest of this article on sciencefriday.com.

Transcript for this radio story will be available after the show airs on sciencefriday.com.

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The harms of smoking cigarettes are pretty clear. Smoking causes cancer as well as heart and lung diseases, and it’s the leading cause of preventable death in the United States.

When it comes to vaping, or electronic cigarettes, the risks are a bit more tricky to parse, especially if you read media reports about them. The outbreak of Vaping Use-Associated Lung Injury, also known as EVALI, in 2019 and 2020 made things even more confusing.

The founders of Juul, the company that mainstreamed vaping in the early aughts, said they wanted to help people kick their smoking habits. But can vapes really help people quit? And how bad are they for you, really? And if you’re addicted to vaping, what’s the best way to stop?

To answer those questions and more, Host Ira Flatow talks with one of the top researchers in the field, Dr. Jamie Hartmann-Boyce, assistant professor of health policy and management at the University of Massachusetts Amherst.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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Scientists determined that Lucy, a human ancestor from 3.2 million years ago, couldn’t have beaten modern humans in a foot race. Also, the Chinese AI company DeepSeek startled industry observers with an efficient new system. But how does it compare with the leading tech?

How Lucy, Our Famous Ancestor, Runs On A Virtual Treadmill

Lucy is one of the most famous fossils—an Australopithecus afarensis who lived about 3.2 million years ago. Her skeleton is about 40% complete, and has been studied since its discovery in 1974. In a quest to learn more about what Lucy’s life may have looked like, scientists estimated what her leg and pelvic muscles were like based on her skeleton. They then put her on a treadmill—virtually, of course.

The findings? Lucy was likely not a natural runner, and the modern human body evolved for improved running performance. Host Flora Lichtman talks to Producer Kathleen Davis about these findings, and other news of the week.

Flora also speaks to Anil Oza, a Sharon Begley Science Reporting Fellow at STAT and MIT, about the latest news on the Trump administration taking down scientific data from the Centers for Disease Control website for mentioning topics like gender, DEI and accessibility. They also discuss the National Institutes of Health resuming grant reviews after two weeks of restrictions imposed by the president.

How DeepSeek’s AI Compares To Established Models

The Chinese company DeepSeek recently startled AI industry observers with its DeepSeek-R1 artificial intelligence model, which performed as well or better than leading systems at a lower cost. The DeepSeek product apparently requires less human input to train, and less energy in parts of its processing—though experts said it remained to be seen if the new model would actually consume less energy overall.

Will Douglas Heaven, senior editor for AI at MIT Technology Review, joins Host Ira Flatow to explain the ins and outs of the new DeepSeek systems, how they compare to existing AI products, and what might lie ahead in the field of artificial intelligence.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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The inner workings of our bodies, particularly what’s happening inside our cells, can be kind of a black box—with countless tiny molecules constantly working and churning to keep us alive. A new technology that blends bioluminescence with cellular machinery may shine some light on the details of their comings and goings and interactions that can be hazy.

Scientists had the bright idea to take that same enzyme that makes fireflies glow and tie it to RNA, the molecule that reads the genetic information in DNA. This developing technology has been used on mice, with the hope that these light-up molecules can help illuminate how viruses replicate or even how memories form in the brain.

Flora Litchtman talks with Dr. Andrej Lupták, professor of pharmaceutical sciences at the University of California Irvine and Dr. Jennifer Prescher, professor of chemistry at the University of California Irvine, about their research on the topic.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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It seems that every few months, there’s an exciting breakthrough in quantum computing, a kind of computing that takes advantage of quantum physics to perform calculations exponentially faster than our most advanced supercomputers. Last December, Google announced that its quantum computer solved a math problem in five minutes—a problem that would’ve taken a normal supercomputer longer than the age of the universe to solve. And earlier this month, Microsoft, coming off a quantum advance in the fall, told businesses to get “quantum-ready” for 2025, saying that “we are right on the cusp of seeing quantum computers solve meaningful problems.”

So, are we on the cusp? Flora Lichtman is joined by Dr. Shohini Ghose, a quantum physicist and professor at Wilfrid Laurier University in Waterloo, Canada and CTO of the Quantum Algorithms Institute, for a quantum computing check-in and a look at when this futuristic technology could start to have an impact on our lives.

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About four and a half years ago, a spacecraft called OSIRIS-REx touched down on the surface of an asteroid called Bennu. It drilled down and scooped up samples of rock and dust and, after several years of travel, delivered those samples back to Earth.

Since then, researchers around the world have been analyzing tiny bits of that asteroid dust, trying to tease out as much information as they can about what Bennu is like and where it might have come from. Two scientific papers published this week give some of the results of those experiments. Researchers found minerals that could have arisen from the drying of an icy brine, and a soup of organic molecules, including ammonia and 14 of the 20 amino acids necessary for life on Earth.

Dr. Danny Glavin and Dr. Dante Lauretta join Flora Lichtman to talk about the samples, what their analysis is revealing, and what those findings could mean for the hunt for life elsewhere in the solar system.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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Published 2025-02-03

The Toxic Aftermath Of An Urban Fire

18 min
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After nearly four weeks of burning, the fires in Los Angeles are almost fully contained, and cleanup is underway. But as the dust literally settles, people in LA are left with major questions, like: What is actually in the ash? What’s in the air? And how do I stay safe?

Flora Lichtman talks with two experts in public health and toxic substance exposure about the chemicals left behind after an urban fire as well as what science needs to be done to fully understand the issue. She speaks with Dr. Rima Habre, associate professor of environmental health and spatial sciences at the University of Southern California in Los Angeles; and Dr. Mark Wilson, director of exposure science at Chemical Insights Research Institute (CIRI) in Marietta, Georgia.

Transcript for this segment will be available after the show airs on sciencefriday.com.

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The outbreak of H5N9 avian influenza occurred at a California duck farm in November 2024. Also, new research pinpoints 298 parts of the genome associated with higher risk of bipolar disorder. This could lead to better treatments.

Another Strain Of Bird Flu Discovered In California

This week, the World Organization for Animal Health reported that it had been notified by the USDA that a November outbreak of highly pathogenic avian influenza on a California duck farm was caused by a strain not before seen in the United States: H5N9. The dominant bird flu strain circulating currently, H5N1, has led to massive culling of bird flocks, has infected dairy cattle, and has killed almost 500 people around the world since 2003. The US reported its first human death from bird flu earlier this month.

Experts stressed that the new strain did not itself appear to be an immediate human threat. But the rise of a new strain is troubling and points to the risk of a viral phenomenon known as “reassortment,” in which different viruses mingled in a host can sometimes exchange bits of viral code, forming new strains.

SciFri’s Charles Bergquist joins Flora Lichtman to talk about H5N9 and other stories from the week in science, including a spacewalk that was meant to include a search for microbes on the outside of the International Space Station, a possible positive side effect of scratching an itch, and the discovery of 66 million-year-old fossilized vomit.

Understanding Bipolar Disorder Through The Genome

Bipolar disorder is one of the most common mental illnesses—it affects an estimated 40 million people worldwide, about 2.8% of the population. Bipolar disorder can cause extreme mood swings, and be debilitating without treatment.

In an effort to untangle the mysteries of where bipolar disorder originates, researchers studied the genomes of more than 40,000 people with the condition. When comparing these genomes to those of people without bipolar disorder, the researchers were able to pinpoint 298 different parts of the genome associated with the mental illness. With this better understanding of the genome, better, more targeted treatments for bipolar disorder may be possible.

Joining Flora to talk about this research is Dr. Niamh Mullins, assistant professor of psychiatric genomics at the Icahn School of Medicine at Mount Sinai in New York.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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Health psychologist Dr. Kari Leibowitz traveled to some of the coldest, darkest places on earth to learn how people there don’t just survive, but thrive in winter. She says that one of the key ingredients is adopting a positive wintertime mindset by focusing on and celebrating the good parts of winter.

Flora Lichtman talks with Dr. Kari Leibowitz, author of How to Winter: Harness Your Mindset to Thrive on Cold, Dark, or Difficult Days, about saunas, cold plunges, candles, and other small ways to make winter a season to look forward to rather than dread. Plus, she responds to some of our audience’s own tips to make the season enjoyable.

What Would You Call The Fun Parts Of Winter?

Do you think “winter doldrums” needs a positive rebrand? Let us know what you would call the winter experience instead by leaving us a voicemail at 1-646-767-6532.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

 

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Birds are the master vocalists of the animal kingdom. They can make a remarkable variety of sounds.

But why is a barred owl more of a baritone, while a cedar waxwing is a soprano?

And what influences a bird’s vocal range, and the kinds of sounds it can make? Beak size? Body size? Geography?

To answer some of these questions, researchers analyzed over 140,000 bird vocalizations from all over the world to try to peck out some kernels of knowledge about bird calls and songs. Their research was recently published in Proceedings of the Royal Society B.

Flora Lichtman talks with Dr. Zuzana Burivalova, assistant professor of forest & wildlife ecology at the University of Wisconsin-Madison about her latest research.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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It’s been five years since the first laboratory-confirmed case of COVID-19 in the U.S., a bleak milestone in the early days of a pandemic that touched the lives of everyone. For the lucky ones, the virus mainly meant more precautions: mask-wearing, the occasional COVID test. But for others, a COVID-19 infection turned into long COVID. This is a chronic condition that lingers long after a COVID infection, and can reduce one’s ability to live their day-to-day life.

It’s been estimated that about 400 million people worldwide have had long COVID. Some researchers say that number is much higher. But there’s a lack of research on successful treatments for long COVID.

Some patients living with the condition have taken things into their own hands. A recent investigation documented the experiences of 13 long COVID patients who tried taking Paxlovid for longer than the typical 5-day course. The patients had mixed results, adding to a growing body of evidence that there will not be one silver bullet for treating the condition.

Joining Ira to talk about the results are two authors of the study, who have both had long COVID for years: Dr. Alison Cohen, assistant professor of epidemiology and biostatistics at the University of California San Francisco, and Dr. Julia Moore Vogel, senior program director at Scripps Research in La Jolla, California.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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A recent study in the journal Nature unveiled new proteins that can neutralize the deadliest of snake venoms. They’re “new” in that they aren’t found in nature—they were created in a lab, dreamed up by AI.

Using AI to discover, or design, the building blocks of drugs is a fast-growing area of research. Another team of scientists out of Philadelphia is using AI to discover new antibiotics by resurrecting long-lost molecules from extinct species like neanderthals and woolly mammoths.

We know what you’re thinking: It sounds too sci-fi to be true.

Flora Lichtman talks with two pioneers in the field about how AI is supercharging drug discovery: Dr. César de la Fuente, bioengineer and presidential associate professor at the University of Pennsylvania in Philadelphia, and Nobel laureate Dr. David Baker, director of the Institute for Protein Design and professor at the University of Washington in Seattle.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

For our Los Angeles listeners: We’re working on a story about the toxins left behind by the fires and we want to hear from you. How is this affecting you? Are you worried about the air and water and soil? How are you approaching clean-up? And what questions do you have?

Leave us a voicemail at 1-646-767-6532 or send us an email at scifri@sciencefriday.com.

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Researchers at the National Institutes of Health say the move has sent fear and confusion throughout the agency. Plus, what's the technology behind meme coins?

Trump Administration Cancels Meetings, Freezes Hiring At NIH

This was President Trump’s first week back in the Oval Office. Along with issuing a flurry of executive orders, his administration has imposed a range of restrictions on the National Institutes of Health, affecting meetings, travel, hiring, funding, and communications. Scientists expressed alarm about what this could mean for ongoing research, with no clear timeline for if or when the freeze would be lifted.

Flora Lichtman is joined by Casey Crownhart, climate editor at the MIT Technology Review, to catch up on this and other big science stories of the week, including what’s coming next this year for nuclear power, why a record amount of snow fell in the Southeast this week, and new research on the surprisingly complex biology of a manta ray tail.

What Exactly Is A Meme Coin And How Does It Work?

A few days before President Trump’s inauguration, he hosted a “crypto ball” in Washington, D.C. That night, he unveiled his very own meme coin—a kind of digital asset that has gained a reputation for facilitating scams. Soon after, first lady Melania Trump also launched her own meme coin. After its launch, Trump’s coin’s market capitalization reached billions of dollars.

This isn’t the first time meme coins have gotten a lot of attention—you might remember Elon Musk joked about another one called Dogecoin on SNL in 2021—but it is the first time that this technology has been used by a sitting president. So what exactly is a meme coin anyway? How does the blockchain play into all this? And how might a president use it differently than an internet celebrity?

To find out more, Flora Lichtman talks with Liz Lopatto, a senior writer at The Verge who covers cryptocurrency and business, about how this market started, how Trump could use meme coins, and where the crypto market could go next.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

 

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Editors at scientific journals are quitting in droves. According to Retraction Watch, a watchdog publication, there have been at least 20 mass resignations since 2023.

So, what’s going on? If you look closely, you’ll notice a common pattern—publishers are cutting back on the number of editors, increasing the number of papers, and charging hefty fees for authors to publish their work.

The most recent mass resignation happened at the Journal of Human Evolution at the end of 2024. Both co-editors in chief and the entire editorial board quit, except for one person.

What does this mean for the future of scientific publishing? Have these resignations made the big publishers change their ways? Is the strict academic publishing system we know in danger?

To answer those questions and more, Ira talks with Dr. Andrea Taylor, former co-editor in chief of the Journal of Human Evolution; and Ivan Oransky, co-founder of Retraction Watch and editor in chief of The Transmitter.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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Rejoice, amateur and professional astronomers: This January is a fantastic time for looking up at the sky.

The flashiest event of the season is also one of the easiest to see without binoculars or a telescope. A “parade of planets”—Venus, Saturn, Jupiter, and Mars—will be visible, and recognizable by their incredible brightness against the night sky. Uranus and Neptune will also be visible, but with a telescope. This string of planets will be visible for all of January.

Additionally, the ATLAS comet, discovered last year by NASA’s Asteroid Terrestrial-impact Last Alert System, has come close enough to the sun—8.3 million miles away—to be visible with binoculars or a telescope. Be careful, though: looking at sunrise or sunset could hurt your eyes.

Astronomer Dean Regas, host of the podcast “Looking Up with Dean Regas,” joins Ira from Cincinnati, Ohio, to discuss the best things the winter night sky has to offer this year, with or without a telescope.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

 

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From down here on Earth, life on the International Space Station seems magnificent: floating through the day, enjoying stunning views out your window, having an experience only a handful of other people will ever get.

But what’s it really like to live up there? How does experiencing 16 sunrises and 16 sunsets every day change your perception of time? How do you cope with being so far from the people you love?

Those are some of the questions explored in the novel Orbital, which won the Booker Prize late last year. In the book, author Samantha Harvey imagines the inner life of astronauts aboard the ISS.

Host Flora Lichtman is joined by Samantha Harvey, along with astronaut Dr. Cady Coleman, who spent almost six months on the Space Station, and is an author herself. They talk about the unexpected mundanities of living in space, how Harvey was inspired to write the book during lockdown, and how astronauts make sense of their new reality when separated from the rest of humanity.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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Since January 7, wildfires have been devastating the Los Angeles area. In the span of 10 days, several different fires, including the Palisades and Eaton fires, have burned more than 40,000 acres and destroyed more than 12,000 structures. At least 25 people have died.

The threat of fire is growing, especially in zones known as the wildland-urban interface, or WUI. That’s where unoccupied wildland and human developments meet and mingle. Think of a city sprawling around a forest, for example. In the US, around one in three homes is in this type of high-risk zone.

So what’s the science behind urban fires? And how do we protect ourselves in the face of them?

Ira Flatow talks with Dr. Kimiko Barrett, senior wildfire researcher and policy analyst at the research group Headwaters Economics in Bozeman, Montana; and Dr. Alexandra Syphard, senior research scientist at the Conservation Biology Institute in San Diego, California.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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The SpaceX rocket carries lunar landers from companies based in Texas and Japan. They could arrive at the moon in the coming months. HPV can cause a variety of cancers, including cervical. New mortality data for women under 25 point to the success of the HPV vaccine.

Rocket Launches With Lunar Landers From 2 Private Companies

On Wednesday, a SpaceX rocket launched carrying payloads from two separate private companies hoping to achieve lunar landings. The pair of landers—one from Japanese company ispace, and one from Texas-based Firefly Aerospace—will take months to reach the moon. Firefly’s lander is scheduled to arrive first, in March, with ispace’s lander planned for a touchdown in late May or early June.

Another SpaceX launch on Thursday, a test flight of the company’s Starship system, had mixed results. The booster returned to earth and was successfully “caught,” but the spacecraft exploded over the Caribbean shortly after launch. That explosion is under investigation.

Jason Dinh, climate editor at Atmos in Washington, D.C., joins Ira to talk about the Wednesday launch and plans for private lunar exploration. They also discuss other stories from the week in science, including the ban of Red Dye #3 an AI approach to snake antivenom, and a study predicting a rise in US dementia cases by 2060.

As Cervical Cancer Deaths Plummet, Experts Credit HPV Vaccine

In 2006, a vaccine for the human papillomavirus (HPV) became widely available to adolescents. HPV is the most common sexually transmitted infection, and it can cause cancers of the mouth, throat, and sexual organs. It’s also the cause of nearly every case of cervical cancer.

Now, almost 20 years after the HPV vaccine was introduced, a study published in JAMA noted a 62% drop in deaths due to cervical cancer in women under 25 in the US: from 50 or 60 deaths per year to 13. This follows earlier research that noted a decrease in cervical precancer and cancer since the introduction of the vaccine.

With HPV vaccine uptake at about 60% for adolescents aged 13-15, a higher uptake could virtually eliminate cervical cancer, experts say. However, childhood vaccination rates have dwindled since the start of the COVID-19 pandemic, sparking concerns about the spread of preventable disease.

Joining Flora Lichtman to talk about this latest study is lead author Dr. Ashish Deshmukh, professor of public health sciences and co-leader of the Cancer Prevention and Control Program at the Medical University of South Carolina in Charleston, South Carolina.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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For years, artificial intelligence companies have heralded the coming of artificial general intelligence, or AGI. OpenAI, which makes the chatbot ChatGPT, has said that their founding goal was to build AGI that “benefits all of humanity” and “gives everyone incredible new capabilities.”

Google DeepMind cofounder Dr. Demis Hassabis has described AGI as a system that “should be able to do pretty much any cognitive task that humans can do.” Last year, OpenAI CEO Sam Altman said AGI will arrive sooner than expected, but that it would matter much less than people think. And earlier this week, Altman said in a blog post that the company knows how to build AGI as we’ve “traditionally understood it.”

But what is artificial general intelligence supposed to be, anyway?

Ira Flatow is joined by Dr. Melanie Mitchell, a professor at Santa Fe University who studies cognition in artificial intelligence and machine systems. They talk about the history of AGI, how biologists study animal intelligence, and what could come next in the field.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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Scientists investigated how the shape of the human body makes hula hooping possible—and what hips and a waist have to do with it. And, the decision for how to proceed with NASA's Mars Sample Return Mission will fall to the incoming administration.

What Makes A Hula Hoop Stay Up?

Hula hooping might appear to be a simple physical activity. But there’s some complex math and physics at play as the hoop goes around your body, and scientists haven’t had a clear understanding of those hidden forces—until now. A team of mathematicians at New York University recently published research into the science of hula hooping in the Proceedings of the National Academy of Sciences.

Flora Lichtman is joined by Olivia Pomerenk, a PhD candidate in mathematics at New York University, and a coauthor of that paper. She talks with Flora about why the motion of hula hooping prevents the hoop from falling down and which body types make for the best hooper.

NASA Considers Cheaper, Faster Ways To Retrieve Mars Samples

NASA’s Mars Sample Return mission is an ambitious project that aims to use the Perseverance rover to collect Martian rocks, sand, and even gulps of Martian air. Then, through a complicated handoff between different spacecraft, it would ferry those samples to Earth.

A 2023 assessment found that the original plan to retrieve the samples would be much more expensive, and take much longer, than initially expected.

This week, NASA announced two options for how to cut costs and bring the samples to Earth by the late 2030s. But the agency did not solidify a plan, leaving it to the next administration to sort out around 18 months from now. Is the project on the rocks?

To get up to speed on the mission, Flora Lichtman talks with Dr. Jim Bell, professor of earth and space exploration at Arizona State University, and distinguished visiting scientist at NASA’s Jet Propulsion Laboratory.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

 

 

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Alcohol poses many risks to our health, including liver damage and driving under the influence.

Now, U.S. Surgeon General Dr. Vivek Murthy has highlighted another risk of drinking alcohol: cancer. In his latest advisory, Murthy detailed the growing body of research showing that drinking alcohol can increase the risk of at least seven types of cancers, those of the mouth, throat, voice box, esophagus, breast, liver, and colon.

He’s also recommended adding a warning to alcohol outlining the connection between alcohol use and cancer.

Ira talks with Dr. Murthy about the science that informed his latest advisory and his parting message for the nation as he ends his term as Surgeon General.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374


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