TWiV 1037: Antibodies, the good (CoV), the bad (Ad), the beautiful
TWiV reviews evidence that symptomatic adenovirus infection leads to thrombocytopenia, thrombosis, and production of anti-platelet factor 4 antibodies similar to the rare disorder seen after immunization with adenoviral vectored COVID-19 vaccines, and a monoclonal antibody isolated from a SARS survivor, following vaccination with a SARS-CoV-2 spike mRNA vaccine, that neutralizes a broad collection of ACE2-binding sarbecoviruses.
Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker
Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email
Become a patron of TWiV!
Links for this episode- MicrobeTV Discord Server
- MicrobeTV store at Cafepress
- Research assistant position in Rosenfeld Lab CBER/FDA (pdf)
- VITT-like disorder after adenovirus infection (NEJM)
- The clot thickens (TWiV 842)
- Lessons from VITT (Nat Rev Immunol)
- Pan-sarbecovirus neutralizing mAb (Sci Adv)
- Letters read on TWiV 1037
- Timestamps by Jolene. Thanks!
Dickson – Rho Ophiuchi nebula showing massive star formation. James Webb Space Telescope Brianne – Question Mark in Space? Kathy – Quammen interview with Walter Isaacson Rich – Chrome Music Lab Vincent – Matters Microbial
Listener PicksTom – The (second) deadliest virus Charles – We Will All Go Together When We Go and So Long Mom (A Song for World War III) Intro music is by Ronald Jenkees
Send your virology questions and comments to twiv@microbe.tv
More description
TWiV reviews evidence that symptomatic adenovirus infection leads to thrombocytopenia, thrombosis, and production of anti-platelet factor 4 antibodies similar to the rare disorder seen after immunization with adenoviral vectored COVID-19 vaccines, and a monoclonal antibody isolated from a SARS survivor, following vaccination with a SARS-CoV-2 spike mRNA vaccine, that neutralizes a broad collection of ACE2-binding sarbecoviruses.
Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker
Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email
Become a patron of TWiV!
Links for this episode- MicrobeTV Discord Server
- MicrobeTV store at Cafepress
- Research assistant position in Rosenfeld Lab CBER/FDA (pdf)
- VITT-like disorder after adenovirus infection (NEJM)
- The clot thickens (TWiV 842)
- Lessons from VITT (Nat Rev Immunol)
- Pan-sarbecovirus neutralizing mAb (Sci Adv)
- Letters read on TWiV 1037
- Timestamps by Jolene. Thanks!
Dickson – Rho Ophiuchi nebula showing massive star formation. James Webb Space Telescope Brianne – Question Mark in Space? Kathy – Quammen interview with Walter Isaacson Rich – Chrome Music Lab Vincent – Matters Microbial
Listener PicksTom – The (second) deadliest virus Charles – We Will All Go Together When We Go and So Long Mom (A Song for World War III) Intro music is by Ronald Jenkees
Send your virology questions and comments to twiv@microbe.tv
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