This Week in Virology

TWiV explains mRNA delivery of mosaic-8 pan-sarbecovirus RBD vaccines, and how toll-like receptor 7 alters the maternal immune landscape during influenza A infection to increase maternal and fetal morbidity,

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Become a patron of TWiV!

• Support science education at MicrobeTV
• Positions in Rosenfeld Lab (email)
• RFK Jr. driving vast inquiry into vaccines (NY Times)
• Indiana plant biologist locked out of lab by school (Science)
• Trump cuts CDC role in PEPFAR (Science)
• Ralph Baric retires (The Assembly)
• Baric to fight NIH funding ban (Science)
• Ebola outbreak in DRC (npr)
• Persistence of Andes virus RNA in human semen (Viruses)
• mRNA delivery of mosaic-8 pan-sarbecovirus RBD vaccines (Cell Rep)
• Science will break your heart (TWiV 920)
• TLR7 and maternal and fetal morbidity during influenza (Sci Adv)
• Letters read on TWiV 1323
• Timestamps by Jolene Ramsey. Thanks!

Kathy – Bloomberg Connects app and What's in Bloom Peony Season 2026 Bloom Tracker Rich – Medpage Today: What you need to know about hantavirus Vincent – Apollo 11 Almost Never Left the Moon

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Daniel Griffin and Vincent Racaniello reviewed the latest developments surrounding the hantavirus outbreak, including new interim guidance from the Centers for Disease Control and Prevention for the management of infectious cases, whether the CDC may be downplaying the significance of the outbreak because of public backlash following the COVID-19 pandemic, before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, benefit of maternal vaccination against RSV for infants, efficacy and safety of a mRNA influenza vaccine how to access and pay for Paxlovid, where to go for answers about long COVID-19, multisystem inflammatory syndrome in children and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• Interim Guidance for Public Health Assessment and Management of People with Potential Exposure to Andes Virus Outbreak (CDC)
• Hantavirus in humans: a review of clinical aspects and management (LANCET: Infectious Diseases)
• "Super-Spreaders" and Person-to-Person Transmission of Andes Virus in Argentina (NEJM)
• Person-to-Person Transmission of Andes Virus in Hantavirus Pulmonary Syndrome, Argentina, 2014 (CDC: Emerging Infectious Diseases)
• Hantavirus on board with Prof. Vincent Racaniello (microbeTV)
• Transcript – Updateon CDC's Hantavirus Response 5/13/2026 (CDC)
• CDC Is Walking a Tightrope With Its Response to Hantavirus (Wall Street Journal)
• What Happened on the Hantavirus Cruise, According to a Doctor On Board (The Atlantic)
• Andes hantavirus outbreak on a cruise ship – an ESCMID Emerging Infections Subcommittee (EIS) rapid assessment (CMI: Clinical Microbiology and Infection)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Big outbreak, bright lights…Measles Dashboard(South Carolina Department of Public Health)
• Utah measles outbreak response (Utah Department of Health and Human Services)
• Utah Measles Dashboard (Utah Department of Health and Human Services)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• USrespiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA)
• WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP)
• FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP)
• Weekly surveillance report: cliff notes (CDC FluView)
• Efficacy and Safety of an mRNA Seasonal Influenza Vaccine in Adults (NEJM)
• OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Diseases (Yale School of Public Health)
• US respiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Respiratory Diseases (Yale School of Public Health)
• Maternal RSV Vaccination, Infant Nirsevimab, or Both: Interim Analysis of a Randomized Trial (Pediatrics)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Life lost due to the COVID-19 pandemic: A model-based cohort analysis of mortality displacement in the registered population of England (PLoS One)
• Where to get pemgarda (Pemgarda)
• EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• Ensitrelvir for Covid-19 Postexposure Prophylaxis in Household Contacts (NEJM)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• Understanding Coverage Options (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Reaching out to US house representative
• Letters read on TWiV 1322
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV explains how cross-reactive anti-prophage antibodies and bacterial heteroresistance is implicated in phage therapeutic failure, and how phages communicate across species to shape microbial ecosystems.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

• Support science education at MicrobeTV
• Positions in Rosenfeld Lab (email)
• Craig Venter dies (Nature)
• Hantavirus outbreak (WHO)
• Hantavirus on board (YouTube)
• HPS 25th anniversary discovery story (EID)
• Phage therapeutic failure unraveled (Nat Med)
• Phages communicate across species (Cell)
• Control of lysis-lysogeny decisions (Trends Micro)
• Arbitrium phages manipulate each other (Cell)
• Elio Schaechter on arbitrium (TWiM 146)
• Letters read on TWiV 1321
• Timestamps by Jolene Ramsey. Thanks!

Brianne – Could this fungus contaminate Mars? Rich – Supernova in a Sideways Spiral Jolene – Virology class communication projects 2026 Vincent – Facts About The Boeing 747 Hump That Will Surprise You

David – My first science video in 3 years Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss the outbreak of Hantavirus on a cruise ship and its potential for person-person transmission, how cessation of funding for global health by the Trump administration has compromised American health and well being, as well as the description of paralytic poliomyelitis outbreaks in Central Africa associated with the administration of nOPV2, before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, association of ear infections in children with RSV, PEMGARDA authorized use for certain immunocompromised individuals where to find PEMGARDA, how to access and pay for Paxlovid, where to go for answers about long COVID-19, multisystem inflammatory syndrome in children and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• Hantavirus Pulmonary Syndrome—The 25th Anniversary of the Four Corners Outbreak (CDC: Emerging Infectious Diseases)
• Outbreak of Hantavirus Infection in the Four Corners Region of the United States in the Wake of the 1997–1998 El Nino—Southern Oscillation (JID)
• Person-to-Person Transmission of Andes Virus in Hantavirus Pulmonary Syndrome, Argentina, 2014 (CDC: Emerging Infectious Diseases)
• Hantavirus cluster linked to cruise ship travel, Multi-country (WHO)
• Hantavirus (WHO)
• Ventilation Upgrade Reduces Fuel Consumption by 10 Percent in Cruise Ships(Halton)
• Person-to-Person Transmission of Andes Virus in Hantavirus Pulmonary Syndrome, Argentina, 2014 (CDC: Emerging Infectious Diseases)
• Incubation Period of Hantavirus Cardiopulmonary Syndrome (CDC: Emerging Infectious Diseases)
• At least 8 sickened in suspected hantavirus outbreak; Andes strain confirmed
• (CIDRAP)
• Hantavirus in humans: a review of clinical aspects and management (LANCET: Infectious Diseases)
• Cruise ship's hantavirus outbreak puts researchers in uncharted territory (Science)
• Hantavirus Response Shows How Trump Cuts Have Compromised U.S. Preparedness (NY Times)
• Hantavirus on board with Prof. Vincent Racaniello (microbeTV)
• Emergence of vaccine-derived poliovirus strains from the novel oral polio vaccine in the Central African Republic (mBio)
• TWiV 1319: An earful of SARS-CoV-2 (microbeTV)
• Poliomyelitis (polio) (WHO)
• The world's largest and ​highest-quality​​ first-party data company (Dynata)
• MMR vaccine hesitancy in a polarized information ecosystem: Results from a cross-sectional survey of US adults (Vaccine)
• CDC communication undermines trust in vaccines (Science)
• F.D.A. Blocked Publication of Research Finding Covid and Shingles Vaccines Were Safe (NY Times)
• Tick Bite Data Tracker (CDC: Ticks)
• Infectious Diseases (POPHIVE: Yale School of Public Health)
• The National Respiratory and Enteric VirusSurveillance System (NREVSS) (CDC: National Respiratory and enteric virus surveillance System)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health)
• Utah measles outbreak response (Utah Department of Health and Human Services)
• Utah Measles Dashboard (Utah Department of Health and Human Services)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Measles (CDC Measles (Rubeola))
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Will the USA lose its measles elimination status? (LANCET)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA)
• WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP)
• FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP)
• Weekly surveillance report: cliff notes (CDC FluView)
• OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Diseases (Yale School of Public Health)
• US respiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Respiratory Diseases (Yale School of Public Health)
• Impact of Respiratory Syncytial Virus Immunization on the Rate of Pediatric Acute Otitis Media: A Time-series Analysis (CID)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• Understanding Coverage Options (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Multisystem inflammatory syndrome in children (MIS-C), United States, 2023–2024 (CID)
• Current status and future perspectives on the mechanistic and pathophysiological understanding of long COVID (Communications Medicine)
• Reaching out to US house representative
• Letters read on TWiV 1320
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV explains the emergence of vaccine-derived poliovirus strains from the novel oral polio vaccine in the Central African Republic, and the infection of spiral ganglion neurons in the inner ear by SARS-CoV-2, which may explain hearing loss in humans.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

• Support science education at MicrobeTV
• Positions in Rosenfeld Lab (email)
• Bernard Roizman dies (U Chicago)
• Craig Venter dies (Sci Am)
• Trump fires National Science Board (AAU)
• It was World Vaccine Week (WHO)
• nOPV2 phenotypically reverts via recombination (mBio)
• SARS-CoV-2 infects inner ear (Cell Rep)
• Letters read on TWiV 1319
• Timestamps by Jolene Ramsey. Thanks!

Kathy – Science of rats and other organisms in the East River Alan – Chronolog citizen science project Vincent – Why Do Train Engines Sometimes Face Backwards?

Chris – Consensus: AI for research Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello note the uncertain future of the National Science Foundation amid shifting U.S. funding priorities and governance; the rise of China as a global research powerhouse; ongoing advances and controversies in vaccines shaped by the World Health Organization and the Centers for Disease Control and Prevention; vaccine policy battles in Florida; European approval of the moderna mCOMBRIAX, COVID-19 and influenza vaccine, the mounting evidence supporting preventive vaccination strategies including that for HPV and the HepB birth dose; the spread of drug-resistant infections and the resurgence of HIV in Zambia; and the enduring public trust in scientists despite political turbulence, before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the efficacy of the influenza vaccine for children, PEMGARDA authorized use for certain immunocompromised individuals where to find PEMGARDA, how to access and pay for Paxlovid, use of remdesivir for RSV, how administration of Paxlovid did not affect hospitalization of high-risk vaccinated patients, where to go for answers about long COVID-19, if SARS-CoV-2 infection may facilitate EBV reactivation, exercise for treating long COVID and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• Entire NSF science advisory board fired by Trump administration (Nature)
• United States v. Arthrex, Inc.(Harvard Law Review)
• United States v. Arthrex Inc. [SCOTUSbrief] (Federalist Society)
• China could be the world's biggest public funder of science within two years (Nature)
• The Vaccine Skeptic in Trump's New C.D.C. Leadership Team (NY Times)
• World Immunization week: Largest catch-up initiative delivers over 100 million childhood vaccinations (WHO)
• Pigs are flying!: Florida Republicans refuse to take up DeSantis bill loosening vaccine mandates (NY Times)
• Moderna Receives European Commission Marketing Authorization for mCOMBRIAX, Moderna's mRNA Combination Vaccine Against Influenza and COVID-19(moderna)
• America First! AIDS Creeps Back in Parts of Zambia, a Year After U.S. Cuts to H.I.V. Assistance (NY Times)
• Emergence of Extensively Drug-Resistant Shigellosis — United States, 2011–2023 (CDC: MMWR)
• Scientists Esteemed by Public, with Vaccine Scientists Seen as Similar to Scientists in General (Annenberg: Public Policy Center, University of Pennsylvania)
• RFK Jr. is holding up $600M in vaccines for poor countries (Politico)
• Trump Withdraws Nomination of Casey Means for Surgeon General (NY Times)
• What? Benefit of preventive strategies like vaccination? Incidence of human papillomavirus infections in women aged 27 years and older in the US: A federated data network study (International Journal of Infectious Diseases)
• Economic Impact of Delaying the Infant Hepatitis B Vaccination Schedule (JAMA Pediatrics)
• Impact of Removing the Universal Hepatitis B Birth-Dose Vaccination in the US (JAMA Pediatrics)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Measles Dashboard (South Carolina Department of Public Health)
• Utah measles outbreak response (Utah Department of Health and Human Services)
• Utah Measles Dashboard (Utah Department of Health and Human Services)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Dangers of measles infection (NY Times)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA)
• WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP)
• FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP)
• Weekly surveillance report: cliff notes (CDC FluView)
• OPTION 2: XOFLUZA $50 Cash Pay Option (Xofluza)
• Influenza Vaccination Coverage Among Nursing Home Residents and Health Care Personnel — United States, 2024–25 Influenza Season (CDC: MMWR)
• Pediatric Vaccine Effectiveness Against Influenza Hospitalization And Outpatient Visits: 2021–2024 (Pediatrics)
• Influenza Vaccine Effectiveness in European Primary Care Pediatric Practices: 2022–2024 (Pediatrics)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Diseases (Yale School of Public Health)
• USrespiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Respiratory Diseases (Yale School of Public Health)
• Impact of universal nirsevimab prophylaxis in infants on hospital and primary care outcomes across two respiratory syncytial virus seasons in Galicia, Spain (NIRSE-GAL): a population-based prospective observational study (LANCET: Infectious Diseases)
• First Report on Remdesivir Use for the Treatment of Respiratory Syncytial Virus in Five Allogeneic Hematopoietic Cell Transplant Recipients (JID)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Oral Nirmatrelvir–Ritonavir for Covid-19 in Higher-Risk Outpatients(NEJM)
• Same Pill, Different Impact — Reassessing the Efficacy of Nirmatrelvir–Ritonavir(NEJM)
• Paxlovid doesn't reduce hospitalization, death rates in vaccinated high-risk COVID outpatients, trial shows (CIDRAP)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• UnderstandingCoverage Options (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia: Columbia University Irving Medical Center)
• The answers: Long COVID
• Acute COVID-19 is associated with altered CD8 T-cells indicative of impaired ability to control Epstein–Barr virus reactivation (Medical Microbiology and Immunology)
• Exercise and Weekly Sirolimus (Rapamycin) in Older Adults: RAPA-EX-01 Randomised, Double-Blind, Placebo-Controlled Trial (Journal of Cachexia, Sarcopenia and Muscle)
• Reaching out to US house representative
• Letters read on TWiV 1318
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV explains a study showing that viral DNA load in blood and saliva varied markedly with age, time of day season, sex, and depended on dozens of genetic loci, and identification of an emerging human eye disease associated with aquatic virus zoonotic infection.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

• Support science education at MicrobeTV
• Positions in Rosenfeld Lab (email)
• DNA virome varies with human genes and environments (Nature)
• Emerging eye infection from aquatic virus (Nat Micro)
• Letters read on TWiV 1317
• Timestamps by Jolene Ramsey. Thanks!

Brianne – Wayback Machine: Internet Archive Rich – Grandparents for Vaccines Alan – On Writing by Stephen King Vincent – The Real Reason The Soviets Lost The Space Race!

Ginny – Dr. Cal Your Science Pal Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello are distressed by RFK Jr's testimony in front of Congress, surges in rotavirus infections and the staggering number of people who believe in unproven claims about vaccines and science, before Dr. Griffin then deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the fatal consequences of measles infection, prevalence of influenza and other respiratory infections in dead people, PEMGARDA authorized use for certain immunocompromised individuals where to find PEMGARDA, how to access and pay for Paxlovid, results from a human RSV challenge study, where to go for answers about long COVID-19, negatively associated school-related outcomes in children and adolescents with long COVID, and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• Kennedy denies being sidelined by the White House (Politico)
• Kennedy continued to back away from his criticismof the measles vaccine (NY Times)
• Rotavirus surges after ACIP removes recommendation for vaccine(Discovermagazine)
• 'Staggering' number of people believe unproven claims about vaccines, raw milk and more (Nature)
• Health is confronting division, confusion, and competing influences (Edelman)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Big outbreak, bright lights…Measles Dashboard(South Carolina Department of Public Health)
• Utah measles outbreak response (Utah Department of Health and Human Services)
• UtahMeasles Dashboard (Utah Department of Health and Human Services)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Dangersof measles infection (NY Times)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA)
• WHO updates all 3 viral strains to be included in fall flu shots(CIDRAP)
• FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP)
• Weekly surveillance report: cliff notes (CDC FluView)
• OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza)
• Prevalenceof influenza and other respiratory viral infections in deceased persons: a population-based observational study over four influenza seasons (Clinical Microbiology and Infection)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Diseases (Yale School of Public Health)
• USrespiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Respiratory Diseases (Yale School of Public Health)
• Maternal RSV vaccination and reduced risk of hospitalisation for babies in England, 2024/25 (ESCMID)
• Viral dynamics of the Respiratory Syncytial Virus during experimental human challenge: insights for transmission and protection(JID)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Clinical and economic benefits of seasonal COVID-19 vaccination in Germany: results from the ROUTINE-COV19 Study, September 2022 to March 2024 (Eurosurveillance)
• Effectiveness and safety of molnupiravir among patients with mild to moderate COVID-19: a prospective, observational, cohort study (Scientific Reports)
• Where to get pemgarda (Pemgarda)
• EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• Understanding CoverageOptions (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulationguidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Divergent inflammatory and neurology-related protein levels in long COVID following primary and breakthrough SARS-CoV-2 infections (Communications Medicine)
• School Difficulties and Long COVID in Children and Adolescents (Academic Pediatrics)
• Reaching out to US house representative
• Letters read on TWiV 1316
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV explains a study showing that the wildlife trade, including live-animal markets, is a major driver of animal-to-human pathogen transmission, and ecological vaccination, a strategy to prevent zoonotic spillover from bats.

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• Support science education at MicrobeTV
• Positions in Rosenfeld Lab (email)
• Bernard Roizman passes (Wikipedia)
• Maturation of a scientist (Ann Rev Virology)
• Wildlife trade drives pathogen transmission (Science)
• Ecological vaccination of bats (Sci Adv)
• Letters read on TWiV 1315
• Timestamps by Jolene Ramsey. Thanks!

Angela – Real-time tracking of pathogen evolution Rich – A Precarious Perch; Suwannee's track; Avian Research and Conservation Institute Alan – Bookshop.org Vincent – The Mysterious 30 Year Journey of Apollo 12

Fernando – Sean M. Carroll's series "The Biggest Ideas in the Universe": "Space, Time, and Motion", and "Quanta and Fields." Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello are dismayed but not surprised by poll results suggesting most Americans doubt vaccine safety, that the head of the CDC and NIH delayed release of a report on the safety of the COVID-19m vaccine, how Nature works to spread disease without the help of the lab and the about face of the Trump administration to nominate a pro-vaccine candidate for CDC director, before Dr. Griffin then deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how the influenza vaccine may attenuate stroke and acute cardiac disease following virus infection, PEMGARDA authorized use for certain immunocompromised individuals where to find PEMGARDA, how to access and pay for Paxlovid, how the COVID-19 pandemic was a 'negative' for one's mortality where to go for answers about long COVID-19, potential therapies for the pediatric long COVID population and contacting your federal government representative to stop the assault on science and biomedical research.

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• More Americans doubt vaccine safety than trust it, POLITICO Poll finds (Politico)
• Top C.D.C. Official Delays Report on Covid Shot's Effectiveness (NY Times)
• Vampire bats in Mexico may feed on CWD-positive deer, spreading disease and posing species-jump threat (CIDRAP)
• Emerging risks at the vampire bat–prion interface: implications for wildlife, livestock, and public health (Journal of Mammalogy)
• Nine-Valent Human Papillomavirus Vaccination and Related Cancers in Males (JAMA: Oncology)
• Trump Administration Eyes Erica Schwartz to Lead CDC (Wall Street Journal)
• Trump to Nominate Doctor Who Has Publicly Supported Vaccines as C.D.C. Director (NY Times)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health)
• Utah measles outbreak response (Utah Department of Health and Human Services)
• Utah Measles Dashboard (Utah Department of Health and Human Services)
• Measles vaccine recommendations from NYP (jpg)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA)
• WHO updates all 3 viral strains to be included in fall flu shots(CIDRAP)
• FDA vaccine advisers recommend adding subclade K to fall shots(CIDRAP)
• Weekly surveillance report: cliff notes (CDC FluView)
• Influenza vaccination attenuates acute myocardial infarction and stroke risk following influenza infection: a register-based, self-controlled case series study, Denmark, 2014 to 2025 (Eurosurveillance)
• OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Diseases (Yale School of Public Health)
• US respiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Respiratory Diseases (Yale School of Public Health)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Deep disadvantage in mortality on the frontlines of the COVID-19 pandemic (Scientific Reports)
• Potter's Field (Wikipedia)
• Where to get pemgarda (Pemgarda)
• EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• UnderstandingCoverageOptions (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulationguidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Interdisciplinary Pediatric Long-COVID Care: A Descriptive Study of Interventions and Health-Related Quality of Life (OFID)
• Reaching out to US house representative
• Letters read on TWiV 1314
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV reviews evidence that influenza standard and high-dose vaccines reduce risk of Alzheimer's dementia, and spread of deltaviruses by a viral Trojan horse mechanism.

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• Support science education at MicrobeTV
• Positions in Rosenfeld Lab (email)
• Dennis O'Callaghan passes (Wikipedia, LSU)
• Reduced dementia risk after influenza vaccine (Neurology)
• Deltaviruses spread via Trojan Horse (Cell)
• Letters read on TWiV 1313
• Timestamps by Jolene Ramsey. Thanks!

Rich – The Path of Artemis II Alan – Climate change is causing cherry blossoms to miss their peak blooms in Japan Vincent – The Fabric of the Cosmos: Space, Time, and the Texture of Reality by Brian Greene

Ann – Artemis II Launch – 7.5 Seconds in Slo-Mo Torsten – 'This feels fragile': how a satellite-smashing chain reaction could spiral out of control Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello are aghast at the CDC's decision to no longer test for rabies and mpox and the revised charter for its the advisory committee on immunization practices, an outbreak of E. coli illness in raw cheese, before Dr. Griffin then deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, clinical practice guidelines for treating COVID-19, PEMGARDA authorized use for certain immunocompromised individuals where to find PEMGARDA, how to access and pay for Paxlovid, if the nasal microbiome modulates COVID-19 disease severity, reviews the use of steroid, antibiotics, anticoagulants and IVIG for treating COVID-19 including long COVID, and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• State public health labs step up as CDC pauses testing for various pathogens, including rabies, mpox (CIDRAP)
• Infectious Diseases Laboratories : Test Directory (CDC)
• Kennedy rewrites the rule for membership on US vaccine advisory panel (Reuters)
• Advisory Committee on Immunization Practices (ACIP): ACIP charter (CDC)
• Quick takes: More E coli tied to raw cheese, drug-resistant Shigella in UK, TB funds for Sudan (CIDRAP)
• Voluntary Recall (FDA)
• E. coli Outbreak Linked to Raw Dairy (CDC: E.coli Infection (Escherichia coli))
• We 100% disagree with the FDA's false "possible link", and extreme allegations (RawFarm USA)
• Risk of Multiple Sclerosis Among Persons With Epstein-Barr Virus–Positive Mononucleosis(Neurology)
• US Scientists Sequence 1,000 Genomes From Measles, a Disease Long Eliminated With Vaccines (KFF HealthNews)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health)
• Utah measles outbreak response (Utah Department of Health and Human Services)
• UtahMeasles Dashboard (Utah Department of Health and Human Services)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• USrespiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA)
• WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP)
• FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP)
• Weekly surveillance report: cliff notes (CDC FluView)
• OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Diseases (Yale School of Public Health)
• USrespiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Respiratory Diseases (Yale School of Public Health)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• 2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19 (CID)
• 2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19: Baricitinib vs. Tocilizumab (CID)
• ImmunobridgingAnalysis of Pemivibart for the Treatment of COVID-19 – A Therapeutic Gap for the Immune Compromised Remains (OFID)
• PEMGARDA® is authorized for use in certain moderately to severely immunocompromised patients to help prevent COVID-19 (Pemgarda)
• Where to get pemgarda (Pemgarda)
• EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• Understanding Coverage Options (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulationguidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Association of nasopharyngeal Dolosigranulum pigrum and Corynebacterium species with post-acute sequelae of SARS-CoV-2 in a longitudinal cohort (Microbiology Spectrum)
• The effect of corticosteroids, antibiotics, and anticoagulants on the development of post-COVID-19 syndrome in COVID-19 hospitalized patients 6 months after discharge: a retrospective follow up study (Clinical and Experimental Medicine)
• Intravenous immunoglobulin treatment for long COVID: a case report of clinical and immunological findings (LANCET: Infectious Diseases)
• Management of Orthostatic Hypotension (JAMA: Internal Medicine) Reaching out to US house representative
• Letters read on TWiV 1312
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

Vincent visits the University of Kansas and speaks with Tony Fehr, Robin Orozco, Juergen Richt and Rob Unckless about their careers and the research ongoing in their laboratories.

Guests: Tony Fehr, Robin Orozco, Juergen Richt, and Rob Unckless

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• Support science education at MicrobeTV
• PARP14 affects replication of multiple viruses (mBio)
• PTPN22 allele enhances innate antiviral immunity (PNAS)
• Disruption of influenza in gene edited pigs (Emerg Microbes Inf)
• Drosophila innubila nudivirus (Virology)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello cover if the "five-second" rule for things that fall on the floor apply to surgical equipment, an outbreak of E. coli illness caused by raw cheese before Dr. Griffin then deep dives into the measles outbreak in South Carolina and Utah, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, strain selection for the 2026-2027 season influenza vaccine by the FDA, if standard or high dose influenza vaccination influences dementia protection, a new variant of SARS-CoV-2, how to access and pay for Paxlovid, specific effects of Paxlovid and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• The "five-second" rule for dropped food: does it apply to dropped medical objects in the operating room? A randomized study of disinfection approaches for contaminated arthroplasty implants (Infection Control & Hospital Epidemiology)
• Whole Genome Sequencing (WGS) Program (FDA)
• Outbreak Investigation of E. coli O157:H7: Raw Cheddar Cheese (March 2026) (FDA)
• Wastewater for norovirus (WasterWater Scan)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health)
• Utah measles outbreak response (Utah Department of Health and Human Services)
• UtahMeasles Dashboard (Utah Department of Health and Human Services)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles(CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• USrespiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA)
• WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP)
• FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP)
• Risk of Alzheimer Dementia After High-Dose vs Standard-Dose Influenza Vaccination (Neurology)
• Weekly surveillance report: clift notes (CDC FluView)
• OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Diseases (Yale School of Public Health)
• USrespiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Respiratory Diseases (Yale School of Public Health)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Respiratory viral infections prime accelerated lung cancer growth (Cell)
• Early Detection and Surveillance of the SARS-CoV-2 Variant BA.3.2 — Worldwide, November 2024–February 2026 (CDC: MMWR)
• Where to get pemgarda (Pemgarda)
• EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• UnderstandingCoverageOptions (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulationguidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Paxlovid shows organ-specific and age-specific impacts on risk of developing post-acute sequelae of COVID-19 (Communications Medicine)
• The Effect of Fluvoxamine and Metformin for Fatigue in Patients With Long COVID (Annals of Internal Medicine)
• Reaching out to US house representative
• Letters read on TWiV 1310
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV explains why human papillomavirus vaccine-induced immunity can block infection, unlike all other vaccines, and how respiratory viral infections such as COVID and influenza prime accelerated lung cancer growth.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

• Support science education at MicrobeTV
• Positions in Rosenfeld Lab (email)
• J. Michael Bishop passes (NY Times)
• Vincent interviews JM Bishop (YouTube)
• David Botstein passes (NY Times)
• Post-attachment neutralization of HPV (npj vaccines)
• HPV vaccine blocks infection (Cancer Discov)
• Respiratory viral infections prime lung cancer growth (Cell)
• Respiratory virus infections awaken metastatic breast cancer (TWiV 1243 )
• SARS-CoV-2 mRNA vaccines sensitize tumors to immunotherapy (TWiV 1265)
• Letters read on TWiV 1309
• Timestamps by Jolene Ramsey. Thanks!

Brianne – Project Hail Mary Rich – After a decade as a Yale hospital janitor, she is now a doctor there Alan – Scientific analysis of jokes in conference talks Vincent – Yuval Noah Harari: Why advanced societies fall for mass delusion

Greg – Changes in Terrestrial N Budgets and Riverine Nitrate-N Yields from Mississippi River Basin Watersheds 2000 to 2020 Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello talk about the resignation of a member of the advisory committee for immunization practices and the irony of his rationale that a judge slandered him, vaccinating dairy cattle against H5N1, illnesses resulting from drinking raw milk and the US norovirus outbreak, which is not cruise related, then Dr. Griffin deep dives into the measles outbreak in South Carolina and Utah, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, safety data of the RSV vaccine for high risk young adults, recognition of unrecognized COVID-19 deaths (but weren't we not allow to call it a COVID-19 in 2020?), retraction of and how the ANTIBIOTIC azithromycin is NOT an antiviral drug, how to access and pay for Paxlovid, long COVID patients with neurocognitive symptoms and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• Confusion abounds over future of US vaccine advisory committee (The Guardian)
• Key Adviser Quits Federal Vaccine Panel (NY Times)
• Vaccinate the vacca? …..Why We Must Vaccinate US Dairy Cattle Against HPAI H5N1(JID)
• Largest Animal Health Emergency in US History Continues as HPAI Hits Indiana Hard (Hoosier AG Today)
• Indiana: More than 350,000 birds killed in massive avian flu outbreak (CIDRAP)
• 5 children receive E. Coli from raw milk; TN dairy farm responds (Local 3 News)
• Quick takes: Measles spike in Utah, 5 kids ill from raw milk, CDC director uncertainty (CIDRAP)
• Increasing Predominance of Norovirus GII.17 over GII.4, United States, 2022–2025 (Emerging Infectious Diseases)
• Wastewater for norovirus (WasterWater Scan)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health)
• Utah measles outbreak response (Utah Department of Health and Human Services)
• Utah Measles Dashboard (Utah Department of Health and Human Services)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles(CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA)
• WHO updates all 3 viral strains to be included in fall flu shots(CIDRAP)
• Weekly surveillance report: clift notes (CDC FluView)
• OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Diseases (Yale School of Public Health)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Respiratory Diseases (Yale School of Public Health)
• Immunogenicity and Safety of the AS01E-adjuvanted Respiratory Syncytial Virus (RSV) Prefusion F Protein Vaccine in Adults Aged 18–49 Years at Increased Risk of RSV Disease Compared with Adults Aged ≥60 Years (CID)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Respiratory viral infections prime accelerated lung cancer growth (Cell)
• Association between COVID-19 vaccination and sudden death in apparently healthy younger individuals: A population-based case-control study (PLoS Medicine)
• Applying machine learning to identify unrecognized COVID-19 deaths recorded as other causes of death in the United States (Science Advances)
• RETRACTED work: Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial (International Journal of Antimicrobial Agents)
• Antibiotic used in COVID patients tied to increased signs of antibiotic resistance (CIDRAP)
• Empiric azithromycin alters the upper respiratory microbiome and resistome without anti-inflammatory benefit in COVID-19 (Nature Microbiology)
• COVID-19 mRNA Vaccination in Pregnancy and Risk of Infection in Early Childhood (Pediatrics)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• Understanding Coverage Options (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Outcomes of Patients with Neurocognitive Symptoms Attending a Long COVID Clinic: A Longitudinal Cohort Study (Journal of General Internal Medicine)
• Outcomes of Patients withNeurocognitive Symptoms Attending a Long COVID Clinic: A Longitudinal Cohort Study (Journal of General Internal Medicine)
• Long COVID Treatment Guide (rthm)
• Reaching out to US house representative
• Letters read on TWiV 1308
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV reviews the structural basis for Rep-mediated adeno-associated virus DNA genome packaging, how influenza virus-infected myeloid cells travel to the heart and infect cardiomyocytes, leading to IFN-fueled heart damage.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

• Support science education at MicrobeTV
• Positions in Rosenfeld Lab (email)
• Robin Weiss passes (ICR)
• Judge strikes down RFK Jr.'s vaccine policies (NYTimes)
• How Rep protein packages AAV DNA (Cell Rep)
• How influenza virus causes heart damage (Immunity)
• Influenza virus hitches a cellular ride to the heart (Cell Host Microbe)
• Letters read on TWiV 1307
• Timestamps by Jolene Ramsey. Thanks!

Brianne – The math of March Madness brackets Kathy – SpaceX launch plume, jellyfish APOD and Cleveland Meteor, map of meteorites fall and a doorbell cam photo Rich – After barista's tips were stolen, strangers showed up with $900 Vincent – What Causes Gravitational Time Dilation? A Physical Explanation.

Charles – They're Made Out Of Meat Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello chat about death of water fowl on Long Island, 'renaming' of the FDA adverse event monitoring system, lawsuits against RFK Jr and HHS for illegal changes in routine immunization practices, before Dr. Griffin deep dives into economic costs of not vaccinating against measles, the measles outbreak in South Carolina, Utah and ICE detention centers, recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, expansion of the RSV vaccine licensure to include high risk yound adults, association between lung cancer and respiratory illnesses, how to access and pay for Paxlovid, effectiveness of vaccination or supplemental vitamin D to reduce the risk of long COVID, and contacting your federal government representative to stop the assault on science and biomedical research.

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• Local waterfowl die-off likely caused by bird flu (The Suffolk Times)
• East End officials respond as dead birds pile up on Long Island shorelines (news 12: Long Island)
• FDA Adverse Event Monitoring System(AEMS)(FDA)
• FDA Launches NewAdverse Event Look-Up Tool(FDA)
• FDA announces AEMS, new adverse-event database to replace VAERS (CIDRAP)
• US cuts broad recommendation for four childhood vaccines including flu (Reuters)
• US CDC deploys staff to curb South Carolina's measles outbreak (Reuters)
• US judge upends Kennedy's overhaul of childhood vaccine policies (Reuters)
• American Academy of Pediatrics, et al v. Robert F Kennedy, Jr, et al (Civil Action No 25-11916-BEM)
• White House Puts RFK Jr.'s HHS on Tighter Leash After MAHA Setbacks(Wall Street Journal)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Big outbreak, bright lights…Measles Dashboard(South Carolina Department of Public Health)
• Utah measles outbreak response (Utah Department of Health and Human Services)
• Utah Measles Dashboard (Utah Department of Health and Human Services)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA)
• WHO updates all 3 viral strains to be included in fall flu shots(CIDRAP)
• Weekly surveillance report: clift notes (CDC FluView)
• OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Diseases (Yale School of Public Health)
• USrespiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Respiratory Diseases (Yale School of Public Health)
• FDA expands approval for RSV vaccine to include younger adults at high risk (FDA)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Respiratory viral infections prime accelerated lung cancer growth (Cell)
• 2024–2025 COVID-19 mRNA Vaccine Effectiveness Against Severe Disease (JID)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• Understanding Coverage Options (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulationguidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Effectiveness of COVID-19 Vaccination and Prior Infections to Reduce Long COVID Risk During the Pre-Omicron and Omicron Periods (CID)
• A Randomized Trial of Vitamin D Supplementation and COVID-19 Clinical Outcomes and Long COVID: The Vitamin D for COVID-19 Trial (The Journal of Nutrition)
• Long COVID Treatment Guide (rthm)
• Reaching out to US house representative
• Letters read on TWiV 1306
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV introduces sunshine virus of carpet pythons and its effect snakes after experimental infection, and development of a new tool to distinguish between naturally ocurring outbreaks and those that arise from lab accidents.

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• Support science education at MicrobeTV
• Positions in Rosenfeld Lab (email)
• IgNobel Prize ceremony moved to Europe (Science)
• Prasad is out of the FDA (again) (npr)
• Sunshine virus in carpet pythons (J Virol)
• Selection preceding epidemics and pandemics (Cell)
• Letter read on TWiV 1305
• Timestamps by Jolene Ramsey. Thanks!

Brianne – Galileo's handwritten notes found in ancient astronomy text Rich – Dungeon Crawler Carl by Matt Dinniman Alan – High-resolution 3D imaging of the USS Monitor by NOAA's new µSAS system Vincent – The Order of Time by Carlo Rovelli

Douglas – Grandparents for vaccines Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss the global spread of the 'eradicated' poliovirus, the suggestion of RFK's autocratic ability to change vaccine policy and the 'resignation' for the second time of CBER director Vinjay Prasad, and zoonotic spillover of viruses without adaptation, before Dr. Griffin deep dives into economic costs of not vaccinating against measles, the measles outbreak in South Carolina, Utah and ICE detention centers, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, VRPBEC meeting for 'flu' vaccine strain selection, how to access and pay for Paxlovid, closing of long COVID treatment centers globally, and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• Polio: Practice enhanced precautions…..but isn't it eradicated? (CDC: Travelers' Health)
• RFK Jr has 'unreviewable' authority to reshape vaccine policy, DOJ lawyer tells judge….'unreviewable' is not even a word! (Reuters)
• Stark Divide: Americans More Confident in Career Scientists at U.S. Health Agencies Than Leaders (Annenberg: Public Policy Center, University of Pennsylvania)
• Divisive F.D.A. Vaccine Regulator Is Resigning…..for the second time in 6 months (NY Times)
• Characteristics and Outcomes of Patients With Hematologic Malignancies Hospitalized With Respiratory Viral Infections (OFID)
• Dynamics of natural selection preceding human viral epidemics and pandemics (Cell)
• Recent pandemic viruses, including SAR-CoV-2, spread directly to people without adaptation, researchers say (CIDRAP)
• Wastewater for measles (WasterWater Scan)
• US CDC deploys staff to curb South Carolina's measles outbreak (Reuters)
• Measles cases and outbreaks (CDC Rubeola)
• Measles Dashboard (South Carolina Department of Public Health)
• Utah measles outbreak response (Utah Department of Health and Human Services)
• UtahMeasles Dashboard (Utah Department of Health and Human Services)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA)
• WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP)
• Weekly surveillance report: cliff notes (CDC FluView)
• OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Diseases (Yale School of Public Health)
• USrespiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Respiratory Diseases (Yale School of Public Health)
• Effectiveness of RSV Vaccines against RSV-Associated Thromboembolic Events (CDC: Emerging Infectious Diseases)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Characteristics of Young Children Hospitalized With Acute Respiratory Failure From Infection With Respiratory Syncytial Virus, SARS-CoV-2, or Both, November 2023–March 2024 (OFID)
• Where to get pemgarda (Pemgarda)
• EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• UnderstandingCoverageOptions (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulationguidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Where are the long COVID clinics? (ScienceNews)
• Left without care: Many Long COVID clinics are closing down in the U.K. (The Sick Times)
• Where have all the Long COVID clinics gone? (The Sick Times)
• Reaching out to US house representative
• Letters read on TWiV 1304
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV reviews an association between shingles vaccination and slower biological aging, and how mucosal immunization in mice provides protection against disease caused by diverse viruses and bacteria.

Subscribe (free): Apple Podcasts, RSS, email

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• Support science education at MicrobeTV
• Positions in Rosenfeld Lab (email)
• Shingles vaccination may slow biological aging (J Gerontol)
• Getting virus classification and nomenclature right (J Virol)
• Mucosal vaccination blocks diverse respiratory diseases (Science)
• Timestamps by Jolene Ramsey. Thanks!

Brianne – I grew up unvaccinated. Now I'm an Immunologist Rich – Horizons from PBS News – The science behind exercise and why it's good for our bodies; The London Busman Study (Cardiac Health) Alan – Waste Wars: The Wild Afterlife of Your Trash, by Alexander Clapp Vincent – America vs the World by Robert Kagan

Anne – Winners of the 2026 Underwater Photographer of the Year Award Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello talk about the health misconceptions that RFK Jr continues to perpetuate and how to combat them, first cases of highly pathogenic influenza in the California elephant seal population before Dr. Griffin deep dives into economic costs of not vaccinating against measles, the measles outbreak in South Carolinaand Utah, ICE detention centers, lack of accurate reporting may prevent the US from losing its status as a country that eliminated measles, immune amnesia from measles infection, influenza strain selection for the 2026-2027 vaccine, recent statistics for RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, how to access and pay for Paxlovid, when to use steroids for treating influenza, long COVID treatment center, where to go for answers to your long COVID questions, clinical trials for long COVID treatment including GLP-1 inhibitors and IVIG and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• Kristen Panthagani, MD, PhD (Substack)
• You can know things! (Substack)
• Kmpanthagani: Kristen Panthagani, MD, PhD Instagram)
• Kristen Panthagani, MD, PhD kmpanthagani (Threads)
• Psychological inoculation improves resilience against misinformation on social media (Science)
• 5 Logical fallacies in the era of RFK Jr. (Substack)
• Tecovirimat for the Treatment of Mpox (NEJM)
• California records avian flu in northern elephant seals (CIDRAP)
• First Cases of Highly Pathogenic Avian Influenza in Northern Elephant Seals Confirmed in California (UC Davis)
• Wastewater for measles (WasterWater Scan)
• The health and economic repercussions of declining MMR coverage in the United States (medRxiv)
• 2025 measles resurgence carries estimated $244 million price tag (CIDRAP)
• US builds case to retain measles elimination status as infections mount (Reuters)
• Expert meeting on US measles elimination status delayed to November (Reuters)
• 'Nearly Every' Child With Measles Suffers This Hidden Threat (Medscape)
• CDC acting director Bhattacharya urges use of measles vaccine (Reuters)
• Measles cases and outbreaks (CDC Rubeola)
• Measles Dashboard (South Carolina Department of Public Health)
• Utah measles outbreak response (Utah Department of Health and Human Services)
• Utah Measles Dashboard (Utah Department of Health and Human Services)
• Escobar: ICE sending sick migrants to El Paso hospitals for quarantine (BorderReport)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA)
• WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP)
• Weekly surveillance report: cliff notes (CDC FluView)
• OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Diseases (Yale School of Public Health)
• US respiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Respiratory Diseases (Yale School of Public Health)
• RSV Detection and Antibiotic Prescribing Decisions for Pediatric Respiratory Tract Infections (JAMA Network)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Where to get pemgarda (Pemgarda)
• EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• Understanding Coverage Options (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulationguidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• SARS-CoV-2Persistence and the Gut Microbiota: New Insights into Long COVID Pathogenesis (MDPI)
• Neither Metformin nor Ursodeoxycholic Acid Effectively Treats Postacute Sequelae of COVID-19 (Annals of Internal Medicine)
• Long COVID: RECOVER-TLC Clinical Trials (Foundation for the National Institute of Health)
• Design and rationale of RECOVER-AUTONOMIC: A randomized platform trial evaluating interventions for Long COVID postural orthostatic tachycardia syndrome (American Heart Journal)
• Dr. Ruth's Newsletter: COVID, Flu & Health News, 3/1/26 (Substack) Reaching out to US house representative
• Letters read on TWiV 1302
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV reviews lymphocytic choriomeningitis virus seroprevalence among urban pregnant women and newborns in Philadelphia, and a functional translation initiation complex encoded in the genome of giant viruses that drives synthesis of viral structural proteins.

Subscribe (free): Apple Podcasts, RSS, email

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• Support science education at MicrobeTV
• Positions in Rosenfeld Lab (email)
• LCMV seroprevalence among pregnant women (Emerg Inf Dis)
• Giant viruses encode functional vIF4F (Cell)
• Ribosomal proteins encoded in viral genomes (virology blog)
• Letters read on TWiV 1301
• Timestamps by Jolene Ramsey. Thanks!

Angela – "The Song of the Cell" by Siddhartha Mukherjee. Kathy – Fitbit for farts (WSJ and 1° article) Rich – The Password That Lets Caterpillars Hide in an Ant's Lair Vincent – Astrophysics for People in a Hurry by Neil deGrasse Tyson

Larry – Get an early start! (primary article) Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss several states and the governor of Pennsylvania suing HHS over changes in the childhood vaccination schedule, the vaccine derived type 2 poliovirus outbreak in Pakistan and implications for the global withdrawal of the oral poliovirus vaccine, and the outbreak of Candida, then Dr. Griffin deep dives into recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, how to access and pay for Paxlovid, when to use steroids for treating influenza, long COVID treatment center, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• States vs RFK Jr and Bhattacharya: changes to the childhood vaccine schedule (Office of the Attorney General, California)
• Surgeon General Nominee Sidesteps Questions on Vaccines at Senate Hearing (NY Times)
• Unqualified failure in polio vaccine policy left thousands of kids paralyzed (Science)
• Clinical and Epidemiological Investigation of Vaccine-Derived Poliovirus Type 2 Outbreak in Pakistan During 2019–2021 (CID)
• Inactivated Polio Vaccine Must Be an Essential Part of Polio Eradication (CID)
• Wastewater for Candida auris: Wastewater (WasterWater Scan)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health)
• Utah Measles Dashboard (Utah Department of Health and Human Services)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: cliff notes (CDC FluView)
• OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Diseases (Yale School of Public Health)
• US respiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Respiratory Diseases (Yale School of Public Health)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• COVID-19 vaccination status during pregnancy and preeclampsia risk: the pandemic-era cohort of the INTERCOVID consortium (eClinical Medicine)
• Where to get pemgarda (Pemgarda)
• EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• Understanding Coverage Options (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• Use of corticosteroids in influenza-associated acute respiratory distress syndrome and severe pneumonia: a systemic review and meta-analysis(Scientific Reports)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulationguidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Reaching out to US house representative
• Letters read on TWiV 1300
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV explains how vaccine-induced thrombotic thrombocytopenia develops from antibodies to adenovirus and somatic hypermutation, and castration by a viral protein tyrosine phosphatase that targets a host cell cycle checkpoint protein.

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• Support science education at MicrobeTV
• Positions in Rosenfeld Lab (email)
• US repeals environmental endangerment finding (Nature)
• Environmental groups sue EPA (Guardian)
• NIAID to drop pandemic preparedness and biodefense (Nature)
• FDA backpedals on Moderna mRNA rejection (npr)
• Mechanism of VITT (NEJM)
• Parasitc castration by a wasp virus protein (PNAS)
• Polydnaviruses (PloS Path)
• Timestamps by Jolene Ramsey. Thanks!

Brianne – The effect of seeing scientists as intellectually humble on trust in scientists and their research Rich – The Great Bridge: The Epic Story of the Building of the Brooklyn Bridge by David McCullough Alan – Recipes from the American South, by Michael Twitty Vincent – Why Returning From Mars ls Impossible – Richard Feynman's Warning Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss reversal of last week's no review decision on a flu mRNA vaccine by Vinjay Prasad, appointment of Jay Bhattacharya as CDC director, no experience required, and already detectable reduction in hepatitis B virus vaccination rates, then Dr. Griffin then deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, how to access and pay for Paxlovid, the consequences of measles infection on immune amnesia (shout out to Immune 26), long COVID treatment center, where to go for answers to your long COVID questions, long COVID effect on fertility and type 2 diabetes and contacting your federal government representative to stop the assault on science and biomedical research.

Click arrow to play Download TWiV 1298 (26 MB .mp3, 43 min) Subscribe (free): Apple Podcasts, RSS, email

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• Whiplash! F.D.A. Reverses Decision and Agrees to Review Moderna's Flu Vaccine
• (NY Times, Wall Street Journal, Access New wire)
• N.I.H. Director Will Temporarily Run C.D.C. in Leadership Shake-Up
• (NY Times)
• Reduction in infant Hepatitis B Immunizations (Oregon State Health Department)
• Why Adenovirus vectored vaccine failed: Adenoviral Inciting Antigen and Somatic Hypermutation in VITT (NEJM)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Big outbreak, bright lights…Measles Dashboard(South Carolina Department of Public Health)
• Measles Outbreak Hits Florida College (NY Times)
• Utah's measles outbreak reaches 300 cases (CIDRAP)
• Measles Is Actively Spreading in SLCo (Salt Lake County Health Department)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles(CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Measles 2025 (NEJM)
• Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens (Science; Immune 26)
• Incomplete genetic reconstitution of B cell pools contributes to prolonged immunosuppression after measles (Science)
• Studies into the mechanism of measles-associated immune suppression during a measles outbreak in the Netherlands (Nature Communications)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: cliff notes (CDC FluView)
• OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Diseases (Yale School of Public Health)
• US respiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• The risk of cardiac disease events after respiratory syncytial virus disease: a systematic literature review and meta-analysis (European Respiratory Review)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• COVID-19 Antiviral Prescription Receipt Among Outpatients Aged ≥65 Years (CDC: MMWR)
• Where to get pemgarda (Pemgarda)
• EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• Understanding Coverage Options (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Assessing the impact of SARS-CoV-2 infection and vaccination on fertility and assisted reproductive techniques outcomes: an umbrella review (Vaccine)
• Long-Term Risk of Incident Type 2 Diabetes Following SARS-CoV-2 Infection: A Population-Based Study in British Columbia, Canada (Diabetes Metabolism Research and Review)
• Reaching out to US house representative
• Letters read on TWiV 1298
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV explains the observation that filamentous virions act as non-infectious interfering particles to modulate papillomavirus infection, and transmission of monkeypox virus from fire-footed rope squirrels to sooty mangabeys.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

• Support science education at MicrobeTV
• Positions in Rosenfeld Lab (email)
• FDA refuses to review Moderna flu mRNA vaccine (CIDRAP)
• Oz measles vaccine call, too little too late? (dw.com)
• Defective human papillomavirus interfering virus particles (J Virol)
• Fire-footed rope squirrel potential MPXV reservoir (Nature)
• Squirrels could be MPXV reservoir (Nature)
• Letters read on TWiV 1297
• Timestamps by Jolene Ramsey. Thanks!

Brianne – Silo TV series Kathy – Ancient RNA expression profiles from the extinct woolly mammoth and Ancient host-associated microbes obtained from mammoth remains Alan – Ubik, by Philip K. Dick Vincent – Starry Messenger by Neil deGrasse Tyson

Beth – Iceland crime fiction authors Yrsa Sigurdardottir and Ragnar Jonasson

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello are shocked by recent events, including Dr. Oz's appeal for measles vaccination, Vinjay Prasad's unilateral rejection of Moderna's mRNA influenza vaccine application, and the increasing number of New World screw worm cases, then Dr. Griffin then deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, how to access and pay for Paxlovid, the number of measles deaths in Mexico, long COVID treatment center, where to go for answers to your long COVID questions, choroid plexus alterations in long COVID association with neuropathologies and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• How Dr. Oz's appeal to get measles vaccine may differ from RFK Jr.'s messaging (ABC News)
• FDA reverses course, refuses to review Moderna's application for new mRNA flu vaccine (CIDRAP)
• Hepatitis B Vaccination at Birth: Safety, Effectiveness, and Public Health Benefit (American Academy of Pediatrics: Pediatrics)
• US Olympic Committee remains 'dialed in' to prevent spread of stomach illness at Winter Games (CNN)
• Oz promotes measles vaccination (NY Times; USA Today; Fortune)
• Screw worm in Mexico (Gobierno de Mexico)
• Mexico reports more human New World screwworm infections (CIDRAP)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Measles outbreak poses risk of 'irreversible' brain damage, health officials warn (Fox News)
• In Mexico, at least 28 have died from measles outbreak that started 2025 (Reuters)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• USrespiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: cliff notes (CDC FluView)
• Influenza vaccination and the risk of myocardial infarction(BMC Publich Health)
• OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Diseases (Yale School of Public Health)
• USrespiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Long-term impact of nirsevimab on prevention of respiratory syncytial virus infection using a real-world global database (Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Where to get pemgarda (Pemgarda)
• EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• Understanding Coverage Options (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Choroid plexus alterations in long COVID and their associations with Alzheimer's disease risks (Alzheimer's & Dementia)
• Reaching out to US house representative
• Letters read on TWiV 1296
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV reviews a survey conducted in Cambodia's floating villages to explore measles vaccination perceptions and willingness to consider novel vaccination approaches, and how a prophage defends against an infecting phage.

Hosts: Vincent Racaniello, Rich Condit, Brianne Barker, and Jolene Ramsey

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

• Support science education at MicrobeTV
• ASV 2026
• Positions in Rosenfeld Lab (email)
• Update on US measles outbreak (npr)
• Tracking Poll on Trust in the CDC and Views of Federal Childhood Vaccine Schedule Changes (KFF)
• Measles vaccination perceptions in Cambodia (J Virol)
• Prophage defends against infecting phage (Cell Host Micro)
• Letters read on TWiV 1295
• Timestamps by Jolene Ramsey. Thanks!

Brianne - Libib book cataloging app Rich - The Mysterious Case of Rudolf Diesel: Genius, Power, and Deception on the Eve of World War I by Douglas Brunt Jolene - Ellie Jameson artwork and Redbubble Vincent - Recursion by Blake Crouch

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update during Ground hog week, Dr. Griffin and Vincent Racaniello are back to discuss the measles outbreak in South Carolina, American Academy of Pediatrics vaccine recommendations and shingles vaccine and the reduction of dementia, then deep dives into recent statistics RSV, influenza and SARS-CoV-2 infections, the Wastewater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, how to access and pay for Paxlovid, estimated effectiveness of this year's COVID-19 vaccine, long COVID treatment center, where to go for answers to your long COVID questions, long COVID in children, the potential benefits of metformin to reduce disease severity following SARS-CoV-2 infection in obese and overweight patients and contacting your federal government representative to stop the assault on science and biomedical research.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

• Grading the groundhogs (National Oceanic and Atmospheric Administration)
• Sand Mountain Sam predicts an early spring (News19)
• All About the AAP Recommended Immunization Schedule (healthychildren.org)
• Recommended Childhood and Adolescent Immunization Schedule: United States, 2026: Policy Statement (American Academy of Pediatrics: Pediatrics)
• Herpes zoster vaccination and incident dementia in Canada: an analysis of natural experiments (LANCET: Neurology)
• Detection of avian flu antibodies in Dutch dairy cow: ECDC risk assessment remains unchanged (European Centre for Disease Prevention and Control)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Big outbreak, bright lights…Measles Dashboard(South Carolina Department of Public Health)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles(CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: clift notes (CDC FluView)
• OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Diseases (Yale School of Public Health)
• USrespiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Estimated Effectiveness of 2024-2025 COVID-19 Vaccination Against Severe COVID-19 (JAMA)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• Understanding Coverage Options (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulationguidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Long COVID associated with SARS-CoV-2 reinfection among children and adolescents in the omicron era (RECOVER-EHR): a retrospective cohort study (LANCET: Infectious Diseases)
• Long COVID is here to stay—even in children (LANCET: Infectious Diseases)
• Early administration of neutralising monoclonal antibodies and post-acute sequelae of COVID-19 (International Journal of Infectious Diseases)
• Preventing Long COVID With Metformin (CID)
• Metformin may reduce risk of long COVID by 64% in overweight or obese adults
• (CIDRAP)
• Effect of Metformin on the Risk of Post-coronavirus Disease 2019 Condition Among Individuals With Overweight or Obese (CID)
• Preventing Long COVID With Metformin (CID)
• New review highlights growing evidence that diabetes drug metformin can prevent long COVID (CIDRAP)
• Reaching out to US house representative
• Letters read on TWiV 1294
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV reviews the finding in Sweden that immunization against cervical cancer with human papillomavirus vaccine also protects the non-immunized, and methyl salicylic acid as a key volatile molecule that attracts parasitoid wasps to rice and other crops to destroy destructive leafhoppers, and is down-regulated by virus infection to enable virus spread.

Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

• Support science education at MicrobeTV
• ASV 2026
• Positions in Rosenfeld Lab (email)
• "Host adaptations to viral infections" International Meeting
• William Foege dies (NY Times)
• Peter Duesberg dies (NY Times)
• US gov't lost over 10,000 PhDs under DJT (Science)
• Herd effect of HPV vaccination (Lancet Pub Health)
• Arboviruses manipulate rice's volatile emissions (Sci Adv)
• Letters read on TWiV 1293
• Timestamps by Jolene Ramsey. Thanks!

Kathy - The Beak of the Finch, by Jonathan Weiner Rich - Washington: A Life by Ron Chernow Vincent - The Man from Beijing by Henning Mankell

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss with disgust the decline and fall of American public health and the rise of "only me" when highlighting completion of the US withdrawal from the WHO and possibility of making IPV and MMR optional vaccines, before Dr. Griffin then deep dives into recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, Europe losing its measles elimination status, first measles death in Mexico, almost 1000 measles cases in South Carolina, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, the effectiveness of this season's influenza vaccine, where to go for answers to your long COVID questions and contacting your federal government representative to stop the assault on science and biomedical research.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

• US completes withdrawal from World Health Organization (AP News)
• Rejecting Decades of Science, Vaccine Panel Chair Says Polio and Other Shots Should Be Optional (NY Times)
• A Frightening Interview (Beyond the Noise)
• Unexplained Pauses in Centers for Disease Control and Prevention Surveillance: Erosion of the Public Evidence Base for Health Policy (Annals of Internal Medicine)
• Wastewater for measles (WasterWater Scan)
• UK among 6 European countries losing measles elimination status (Dougall MD: DG Alerts)
• European Regional Verification Commission for Measles and Rubella Elimination (RVC) (WHO: Europe)
• Measles Outbreak Associated with an Infectious Traveler — Colorado, May–June 2025 (CDC: MMWR)
• South Carolina measles cases hit 789, surpassing Texas' 2025 outbreak total (Reuters)
• Measles cases and outbreaks (CDC Rubeola)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• States across the country report first measles cases of year(CIDRAP)
• First measles death confirmed in Mexico in 2026 (Mexico News)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: cliff notes (CDC FluView)
• Influenza Vaccine Effectiveness Among Children With and Without Underlying Conditions(Pediatrics)
• OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Diseases (Yale School of Public Health)
• US respiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Effectiveness and Durability of the BNT162b2 KP.2 vaccine against COVID-19 Hospitalization and Emergency Department or Urgent Care Encounters in US Adults (OFID)
• Where to get pemgarda (Pemgarda)
• EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• Understanding Coverage Options (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Association of Nirmatrelvir-ritonavir with intubation or mortality risks in severe COVID-19 patients (BMC Infectious Diseases)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulationguidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Reaching out to US house representative
• Letters read on TWiV 1292
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV explains emergence of a neurovirulent double recombinant from the 'improved' nOPV2 in Uganda, and efficiency of viral entry determined whether cells are latently or lytically infected with cytomegalovirus.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

• Support science education at MicrobeTV
• ASV 2026
• Positions in Rosenfeld Lab (email)
• nOPV2 neurovirulent recombinant in Uganda (Nat Micro)
• 2023 IMB report on polio eradication
• Viral entry shapes HCMV latency establishment (Nat Comm)
• Letters read on TWiV 1291
• Timestamps by Jolene Ramsey. Thanks!

Brianne – Dark Matter by Blake Crouch Rich – Sequoiadendron giganteum; Sequoia & Kings Canyon National Park Alan – The Murderbot Diaries book series, by Martha Wells Vincent – Surely You're Joking, Mr. Feynman!

Rocky – Cheetah mummies found in cave (Nature, National Geographic)

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss screwworm, how the shingles vaccination slows biological aging (for all of you who want to reset 'the clock' and live forever…..you know who you are Musk, Bezos) and getting one dose of the HPV vaccine, then Dr. Griffin then deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how losing our elimination status is the cost of doing business (going for broke is never a good business model !) where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, the effectiveness of this season's influenza vaccine, where to go for answers to your long COVID questions and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• New World Screwworm: Outbreak Moves into Northern Mexico……with an official tag "This is an official CDC Health Advisory" (CDC: Health Alert Network)
• Association between shingles vaccination andslower biological aging: Evidence from a U.S. population-based cohort study (The Journals of Gerontology series A)
• Noninferiority of One HPV Vaccine Dose to Two Doses (NEJM)
• Herd effect of human papillomavirus vaccination on incidence of high-grade cervical lesions: (LANCET: Public Health)
• Confirmations of Highly Pathogenic Avian Influenza in Commercial and Backyard Flocks (USDA: Animal and Plant Health Inspection Service)
• Detections of Highly Pathogenic Avian Influenza in Wild Birds (USDA: Animal and Plant Health Inspection Service)
• Delaware, Georgia see major commercial avian flu outbreaks (CIDRAP)
• Wastewater for measles (WasterWater Scan)
• Notes from the Field: Wastewater Surveillance for Measles Virus During a Measles Outbreak — Colorado, August 2025 (CDC: MMWR)
• Notes from the Field: Retrospective Analysis of Wild-Type Measles Virus in Wastewater During a Measles Outbreak — Oregon, March 24–September 22, 2024 (CDC: MMWR)
• Measles cases and outbreaks (CDC Rubeola)
• Measles vaccine recommendations from NYP (jpg)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Utah measles total rises to 216; CDC deputy director says losing elimination status'cost of doing business' (CIDRAP)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Assessing MMR vaccination coverage gaps in US children with digital participatory surveillance (Nature Health)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: clift notes (CDC FluView)
• Effectiveness of influenza vaccination to prevent severe disease: a systematic review and meta-analysis of test-negative design studies (CMI: Clinical Microbiology and Infection)
• Interim vaccine effectiveness against influenza virus among outpatients, France, October 2025 to January 2026 (Eurosurveillance)
• Moderate protection from vaccination against influenza A(H3N2) subclade K in Beijing, China, September to December 2025 (Eurosurviellance)
• Current flu vaccine provides moderate protection against severe disease, interim analyses suggest (CIDRAP)
• OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Diseases (Yale School of Public Health)
• USrespiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virusnfection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Where to get pemgarda (Pemgarda)
• EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• UnderstandingCoverageOptions (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulationguidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID Reaching out to US house representative
• Letters read on TWiV 1290
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV explains how the dengue virus protein NS1 alters Aedes aegypti midgut permeability and favors virus dissemination, and achieving a complete hepatitis B virus cure in chronic hepatitis B virus-infected humanized mice by using a capsid assembly modulator.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

• Support science education at MicrobeTV
• ASV 2026
• Positions in Rosenfeld Lab (email)
• Dengue virus NS1 alters mosquito midgut permeability (mBio)
• HBV cure with a capsid assembly modulator (Cell Host Microbe)
• Letters read on TWiV 1289
• Timestamps by Jolene Ramsey. Thanks!

Angela – How hibernating bears maintain muscle mass Alan – The flood of Chinese grad students in the 2000s was a boon to US students. Vincent – Feynman Lectures on Physics

David – Stewart Cheifet, Host of TV's 'Computer Chronicles,' Dies at 87 Charles – Last Year, and the Year to Come

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello are bewildered and dismayed by RFK Jr's announced changes in the routine childhood immunization schedule, though not unpredicted, and highlight the science and evidence which eviscerate these changes, then deep dives into recent statistics on the measles epidemic- in particular in South Carolina, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, estimated societal burden of COVID-19 illness, deaths and hospitalizations, benefit of maternal COVID-19 vaccination, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, neurodevelopmental consequences of in-utero SARS-CoV-2 infection and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• 7 great Danish cheeses you should know (Cheese Professor)
• Norovirus in on the rise! (WasterWater Scan)
• Maternal Vaccine Receipt and Infant Hospital and Emergency Visits for Influenza and Pertussis (JAMA Open)
• TUESDAY MEASLES UPDATE: DPH Reports 124 New Measles Cases in Upstate, New Public Exposures, and Upcoming Vaccination Opportunities (South Carolina: Department of Public Health-they have one?)
• Measles cases soar in South Carolina, top 400 (CIDRAP)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• USrespiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: cliff notes (CDC FluView)
• North Dakota confirms pediatric flu deaths as some states note surge in flu activity (CIDRAP)
• OPTION 2: XOFLUZA $50 Cash Pay Option (Xofluza)
• The Best Flu Drug Americans Aren't Taking (The Atlantic)
• Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season(FDA)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Diseases (Yale School of Public Health)
• Impact of universal nirsevimab prophylaxis in infants on hospital and primary care outcomes across two respiratory syncytial virus seasons in Galicia, Spain (NIRSE-GAL): a population-based prospective observational study (Lancet: Infectious Diseases)
• Interim Safety of RSVpreF Vaccination During Pregnancy (JAMA)
• Pfizer's RSV vaccine safe to use during pregnancy, study suggests (CIDRAP)
• USrespiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV)
• Evaluating the Effectiveness of 2024–2025 Seasonal mRNA-1273 Vaccination Against COVID-19-Related Hospitalizations and Medically Attended COVID-19 Among Adults Aged ≥ 18 years in the United States: An Observational Matched Cohort Study (Infectious Diseases and Therapy)
• Where to get pemgarda (Pemgarda)
• EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• UnderstandingCoverageOptions (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• Use of corticosteroids in influenza-associated acute respiratory distress syndrome and severe pneumonia: a systemic review and meta-analysis(Scientific Reports)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulationguidelines (hematology.org
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Incidence and Severity of Postacute Sequelae of SARS-CoV-2 Infection in the Omicron Era: A Prospective Cohort Study (JID)
• Reaching out to US house representative
• Letters read on TWiV 1288
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

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Content in this podcast should not be construed as medical advice.

TWiV explain the tracing of 2500 years of human betaherpesvirus 6A and 6B diversity through ancient human DNA, the effect of shingles vaccination at different stages of the dementia disease course.

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• Letters read on TWiV 1287
• Timestamps by Jolene Ramsey. Thanks!

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Content in this podcast should not be construed as medical advice.