This Week in Virology

TWiV explains the 1953 paper by Watson & Crick proposing a structure for DNA, and the role of Epstein-Barr virus in triggering the autoimmune disease systemic lupus erythematosus.

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• Support science education at MicrobeTV
• Immune 100 live at the Incubator
• CDC revives debunked 'link' between childhood vaccines and autism (npr)
• A structure for deoxyribose nucleic acid (Nature pdf)
• Three Papers, Three Lessons (Am J Resp Crit Care Med)
• Discovery of Double Helix (Crick Papers)
• Jim Watson was blinded by DNA (NY Times)
• What Rosalind Franklin contributed (Nature)
• EBV reprograms autoreactive B-cells in lupus (Sci Transl Med)
• EBV and the making of lupus (Sci Transl Med)
• Timestamps by Jolene Ramsey. Thanks!

Brianne – Virus snowflakes Kathy – When "Physic(k)s Lost Its 'k' and other Language Quarks Vincent – The Peripheral by William Gibson

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello are dismayed by the changes on CDC vaccine website positively stating the link between autism and vaccination, the finding of wild type poliovirus 1 in Germany, Marburg virus in Ethiopia, decimation of the elephant breeding colony by H5N1 and the first human case of H5N5 influenza virus infection before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, antibody escape by seasonal flu viruses, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, if resistance exercise aids in recovery from long COVID and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• Autism and Vaccines (CDC: Vaccine Safety)
• A new road to eradication- WPV 1 in Germany from Afghanistan (Reuters)
• Ethiopia confirms first outbreak of Marburg virus disease (WHO: Ethiopia)
• Highly Pathogenic Avian Influenza Viruses (HPAIV) Associated with Major Southern Elephant Seal Decline at South Georgia (Communications Biology)
• Avian flu has decimated world's largest breeding colony of southern elephant seals (CIDRAP)
• Washington resident is infected with a different type of bird flu (AP News)
• Pelagic Seabirds (OceanAminals)
• That sounds far away: Multiple transatlantic incursions of highly pathogenic avian influenza clade 2.3.4.4b A(H5N5) virus into North America and spillover to mammals (Cell Reports)
• Regional voices, different choices: Parents' and caregivers' HPV vaccine attitudes in the northeast and Southeast United States (Vaccine)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Measles (CDC Measles (Rubeola))
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: cliff notes (CDC FluView)
• ACIP Recommendations Summary (CDC: Influenza)
• Emergence of seasonal influenza A(H3N2) variants with immune escape potential warrants enhanced molecular and epidemiological surveillance for the 2025–2026 season (University of Toronto Press)
• Types of Influenza Viruses (CDC: Influenza (flu))
• With an absent CDC and mismatched 'subclade K' flu strain, experts face upcoming season with uncertainty (CIDRAP)
• Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season(FDA)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Diseases (Yale School of Public Health)
• US respiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Long-term impact of nirsevimab on prevention of respiratory syncytial virus infection using a real-word global database (Journal of Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Estimating Risk of Guillain-Barré Syndrome in US Medicare-Enrolled Older Adults Following Medically Attended Respiratory Syncytial Virus Disease (CID)
• FDA Requires Guillain-Barré Syndrome (GBS) Warning in the Prescribing Information for RSV Vaccines Abrysvo and Arexvy: FDA Safety Communication (FDA)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV)
• COVID-19 vaccination is associated with reduced complications in pediatric patients with atopic dermatitis (Annals of Allergy, Asthma and Immunology)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• Risk mitigation of shared room ventilation and filtration on SARS-CoV-2 transmission: a multicenter test-negative study (Infection Control and Hospital Epidemiology)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• Understanding Coverage Options (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Resistance Exercise Therapy After COVID-19 Infection(JAMA Open Network)
• Reaching out to US house representative
• Letters read on TWiV 1272
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

Vincent visits Virginia Tech for the CeZAP Symposium and speaks with XJ Meng and Kylene Kehn-Hall about their research on hepatitis E virus and Rift Valley fever virus.

Host: Vincent Racaniello

Guests: XJ Meng and Kylene Kehn-Hall

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Become a patron of TWiV!

• Support science education at MicrobeTV
• Immune 100 live at the Incubator
• Hepatitis E virus (Curr Op Micro)
• Rift Valley fever virus NSs and autophagy (PLoS Path)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello record from the ASTMH meeting in Toronto and discuss continuing avian flu outbreaks, the continued global measles outbreak, the effectiveness of high and low doses of the influenza vaccine before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, children hospitalizations following COVID-19 and influenza vaccination, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• Five new avian flu outbreaks confirmed in ducks, turkeys in 3 US states (CIDRAP)
• Confirmation of highly pathogenic Avian Influenza in Commercial and Backyard flocks (USDA: Animal and Plant Health Inspection Service)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Measles (CDC Measles (Rubeola))
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: clift notes (CDC FluView)
• ACIP Recommendations Summary (CDC: Influenza)
• Effectiveness of high-dose influenza vaccine against hospitalisations in older adults (FLUNITY-HD) (LANCET)
• Relative effectiveness of the high-dose versus standard-dose influenza vaccines for the prevention of laboratory-confirmed influenza among Italian older adults during three recent seasons (International Journal of Infectious Diseases)
• Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Diseases (Yale School of Public Health)
• US respiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Long-term impact of nirsevimab on prevention of respiratory syncytial virus infection using a real-word global database (Journal of Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV)
• COVID-19 and influenza deaths in Australian children 2018-2023: a national case analysis (Journal of Pediatric Infectious Diseases Society)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• Understanding Coverage Options (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID Reaching out to US house representative
• Letters read on TWiV 1270
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV reviews the passing of James D. Watson, the research that showed human papillomaviruses to be present in genital and laryngeal papillomas and in some cervical cancers, and influenza virus infection, shedding and symptoms in a human challenge study.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

• Support science education at MicrobeTV
• Immune 100 live at the Incubator
• James D. Watson dies (NY Times)
• Russian translation of TWiV 1024 (Medium)
• Canada's new budget aims to lure US researchers (Science)
• Bird flu surging and spreading while US agencies are asleep (npr)
• US slashed WHO budget, now flu surveillance is suffering globally (npr)
• HPV sequences in papillomas and cervical cancers (PNAS)
• zur Hausen Nobel Prize 2008 (Nobel)
• Vincent interviews zur Hausen (YouTube)
• Influenza virus infection, shedding, and disease in humans (J Virol)
• Timestamps by Jolene Ramsey. Thanks!

Brianne – Pandemic board game Rich – Whiskey Fungus Fed by Jack Daniel's Encrusts a Tennessee Town Alan – Rats can snatch bats out of the air and eat them Vincent – 7 basic science discoveries that changed the world

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello discusses the link between in utero SARS-CoV-2 infection and poor neurodevelopment outcomes, the use of an mRNA vaccine as an anti-cancer therapy, why one should receive the HPV vaccine, asymptomatic H5N1 isolations in humans, and H5N1 on turkey farms, before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how two vaccinated physicians became infected with measles, effective of COVID-19 vaccine for children, where to find PEMGARDA, how to access and pay for Paxlovid, can you be retreated with Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, how a specific antibody type may associate with recovery from long COVID, if use of a probiotic is helpful to treat mild COVID-19, if vaccination helps prevent long in adolescents and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• Neurodevelopmental Outcomes of 3-Year-Old Children Exposed to Maternal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Utero (Obstetrics & Gynecology)
• SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade (Nature)
• TWiV 1267: A cancer vaccine and an mpox treatment (microbeTV: TWiV1267)
• Cancers Caused by HPV (CDC: Human papillomavirus (HPV))
• Circulating tumor human papillomavirus DNA whole genome sequencing enables human papillomavirus-associated oropharynx cancer early detection (Journal of National Cancer Institute)
• Impact of Vaccinating Adult Women Who Are HPV-Positive or with Confirmed Cervical SIL with the 9-Valent Vaccine (Viruses)
• ACIP Shared Clinical Decision-Making Recommendations (CDC: Advisory Committee on Immunization Practices (ACIP))
• HPV Vaccination Recommendation (CDC: Vaccines & Immunizations)
• Asymptomatic Human Infections With Avian Influenza A(H5N1) Virus Confirmed by Molecular and Serologic Testing (JAMA: OPEN Network)
• Review: Human H5N1 avian flu cases can be asymptomatic, and the virus likely spreads among people (CIDRAP)
• Avian flu strikes turkey farms in Dakotas, large egg facility in California (CIDRAP)
• Another Doctor at Ichilov Contracts Measles After Treating Unvaccinated Child (gov.il)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Measles (CDC Measles (Rubeola))
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: clift notes (CDC FluView)
• ACIP Recommendations Summary (CDC: Influenza)
• Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Diseases (Yale School of Public Health)
• US respiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV)
• Vascular and inflammatory diseases after COVID-19 infection and vaccination in children and young people in England (LANCET: Child & Adolescent Health)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• Understanding Coverage Options (PAXCESS)
• Real-World Effectiveness of Nirmatrelvir-Ritonavir in Preventing Coronavirus Disease 2019–Associated Hospitalization (CID)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• SARS-CoV-2 spike-specific IgG4 class switching associates with clinical recovery in Long COVID (Journal of Infection)
• Efficacy of Lactococcus lactis Strain Plasma in Patients with Mild COVID-19 (Infectious Diseases and Therapy)
• Preventive effect of vaccination on long COVID in adolescents with SARS-CoV-2 infection (Vaccine)
• Reaching out to US house representative
• Letters read on TWiV 1268
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV discusses the impact of vaccinating with Gardasil-9 adult women who are human papillomavirus positive or with confirmed squamous intraepithelial lesions, and human monoclonal antibodies that target the monkeypox virus A35 protein which protect against lethal disease.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

• Support science education at MicrobeTV
• Immune 100 live at the Incubator
• Long tailed macaques are now officially endangered (Science)
• Iceland now has mosquitoes (npr)
• Impact of Gardasil-9 on adult women who are HPV+ or SIL+ (Viruses)
• Human mAbs that protect against mpox disease (Cell)
• Timestamps by Jolene Ramsey. Thanks!

Brianne – Civet coffee: The real chemistry behind this bizarre luxury drink Kathy – Astronomy photographer of the year awards Rich – Katherine Swan Ginsburg Humanism in Medicine Program Alan – Parasitic worms can use static electricity to latch onto flies midair Vincent – How to get the best night's sleep: what the science says

Bradon – Elevated Access

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello ponder the nomination of Casey Means for Surgeon General by President Trump, how mRNA vaccines may enhance effectiveness of check point inhibitor cancer therapies, if viral infection associates with cardiac disease, H5N1 isolation from backyard birds and turkey farms, and the effectiveness of the COVID-19, RSV and influenza vaccines before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, if revaccination with the mRNA RSV vaccine is effective, how effective today's COVID-19 vaccine is for protection against severe disease following infection with current viral variants, where to find PEMGARDA, how to access and pay for Paxlovid, can you be retreated with Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• The Challenge of Malignancies in HIV-1, Beyond Immune Activation and Back to Decreased Immune Surveillance (Journal of AIDS & Clinical Research)
• SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade (Nature)
• TWiV 1265: mRNA vaccines make cancer treatment great again (microbeTV: TWiV 1265)
• Viral Infections and Risk of Cardiovascular Disease (Journal of the American Heart Association)
• Confirmations of Highly Pathogenic Avian Influenza in Commercial and Backyard Flocks (USDA: Animal and Plant Health Inspection Service)
• Three large turkey farms in Minnesota hit with H5N1 avian flu (CIDRAP)
• Updated Evidence for Covid-19, RSV, and Influenza Vaccines for 2025–2026 (NEJM)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Measles vaccine recommendations from NYP (jpg)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: Cliff notes (CDC FluView)
• ACIP Recommendations Summary (CDC: Influenza)
• Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Diseases (Yale School of Public Health)
• US respiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Safety, Tolerability, and Immunogenicity of Revaccination With mRNA-1345, an mRNA Vaccine Against RSV, Administered 12 Months Following a Primary Dose in Adults Aged ≥50 Years (CID)
• Vaccine effectiveness of a bivalent respiratory syncytial virus (RSV) pre-F vaccine against RSV-associated hospital admission among adults aged 75–79 years in England (LANCET: Infectious Diseases)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV)
• Association of 2024–2025 Covid-19 Vaccine with Covid-19 Outcomes in U.S. Veterans (NEJM)
• Durability of 2024-2025 COVID-19 Vaccines Against JN.1 Subvariants (JAMA: Internal Medicine)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• Understanding Coverage Options (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Reaching out to US house representative
• Letters read on TWiV 1266
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV explains studies showing that SARS-CoV-2 mRNA vaccines improve life span of cancer patients on checkpoint immunotherapy, and broad immunity conferred by a vaccine central in A(H5) influenza antigenic space.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

• Support science education at MicrobeTV
• Immune 100 live at the Incubator
• SARS-CoV-2 mRNA vaccines sensitize tumors to checkpoint immunotherapy (Nature)
• People with some cancers live longer after mRNA vaccines (Nature)
• Immune checkpoint inhibitors (NCI)
• Broad immunity from influenza H5 vaccine (Nature)
• Derek Smith on antigenic cartography (TWiV 99 at 2:53)
• Letters read on TWiV 1265
• Timestamps by Jolene Ramsey. Thanks!

Kathy – Permethrin-treated baby wraps for malaria prevention and Phil Sharp and the Biotech Revolution Rich – Lydia Fairchild; Tetragametic Chimerism (NEJM) Alan – Warning Signs Vincent – radio.garden thanks to Kim!

Jamie – SkyCards by Flightradar24

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello are distressed by the continuing government shutdown, first locally acquired chikungunya virus infection, President Trump's suggestion for removing aluminum from vaccines, H5N1 isolation from backyard birds and turkey farms, and the suggestion of establishing an alternative to the CDC's MMWR and asymptomatic measles infections before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the quarantining in the US due to measles, access to anti-influenza antiviral, where to find PEMGARDA, how to access and pay for Paxlovid, can you be retreated with Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, if colchicine is effective for long COVID, and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• New York health officials confirm state's first locally acquired case of chikungunya virus (AP News)
• Trump Rattles Vaccine Experts Over Aluminum (NY Times)
• Aluminum-Adsorbed Vaccines and Chronic Diseases in Childhood (Annals of Internal Medicine)
• Three large turkey farms in Minnesota hit with H5N1 avian flu (CIDRAP)
• Confirmations of Highly Pathogenic Avian Influenza in Commercial and Backyard Flocks (USDA: Animal and Plant Health Inspection Service)
• Jeffrey Lee McLean (California.No)
• California mpox cases raise concerns. But health officials say the risk remains low (AP News)
• 'Alternative' to CDC's Flagship Journal in the Works (MEDPAGE TODAY)
• Measles without rash during acute febrile illness surveillance in Tanzania, 2023-2024 (CID)
• Frustration grows amid measles outbreak quarantines across several states (NBC News)
• More Than 100 Cases of Measles Reported in Utah and Arizona (NY Times)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine recommendations from NYP (jpg)
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: clift notes (CDC FluView)
• ACIP Recommendations Summary (CDC: Influenza)
• American Academy of Pediatrics
• Flu and Children (CDC: Influenza (flu))
• Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season(FDA)
• Roche to sell flu pill for $50 to cash-paying US patients (Reuters)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Evidence to Recommendations Framework (EtR): RSV Vaccination in Adults Aged 50–59 years (CDC: National Center for Immunization and Respiratory Diseases)
• Efficacy and safety of respiratory syncytial virus vaccines (Cochrane Library)
• Estimated Vaccine Effectiveness for Respiratory Syncytial Virus–Related Acute Respiratory Illness in Older Adults (CID)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• Understanding Coverage Options (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Effectiveness of Colchicine for the Treatment of Long COVID(JAMA Internal Medicine)
• Reaching out to US house representative
• Letters read on TWiV 1264
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV reviews continuing US measles outbreak, host and genetic variations that regulate antibody responses to hepatitis C virus, and varicella-zoster reactivation and the risk of dementia.

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• Support science education at MicrobeTV
• Mass firings at CDC (Time)
• Measles cases continue to climb in US (NPR)
• Immune 100 at The Incubator (Eventbrite)
• Viral and host variations modulate antibody responses against HCV (Cell Rep)
• VZV reactivation and risk of dementia (Nature Med)
• Taking a shot at dementia (TWiV 1207)
• Demented and crass (TWiV 1249)
• Letters read on TWiV 1263
• Timestamps by Jolene Ramsey. Thanks!

Angela – 'Am I redundant?': how AI changed my career in bioinformatics Brianne – OpenSpace and their YouTube Channel Alan – Coral City Camera – live view of a reef in Biscayne Bay, FL (and NPR story on it). Vincent – Neck pain relief exercises with Dr. Adam Fields

Listener Pick

Greg – AI: What could go wrong? and An AI System With Detailed Diagnostic Reasoning Makes Its Case

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello are dismayed by the government shutdown, the firings at the CDC including EIS agents, H5N1 isolation from backyard birds and its stability in raw milk and cheese, before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the quarantining of college students in the US due to measles, Japan's declaration of a national influenza outbreak, effectiveness of the influenza and COVID vaccines, where to find PEMGARDA, how to access and pay for Paxlovid, can you be retreated with Paxlovid, long COVID treatment center, results from PLATCOV studies- still no antiviral activity attributed to ivermectin, where to go for answers to your long COVID questions, long COVID in pediatrics, patient reported outcomes from the STOP-PASC clinical trial, contacting your federal government representative to stop the assault on science and biomedical research and the listener reminder that measles vaccine in those with interferonopathy may result in severe adverse affects.

Become a patron of TWiV!

• Trump Administration Lays Off Dozens of C.D.C. Officials (NY Times)
• CDC walks back hundreds of firings as US shutdown persists (Yahoo News/ Reuters)
• CDC battered by government shutdown firings, while some are rescinded (STAT 10)
• Confirmations of Highly Pathogenic Avian Influenza in Commercial and Backyard Flocks (USDA: Animal and Plant Health Inspection Service)
• Flurry of H5N1 activity noted in commercial poultry, wild birds(CIDRAP)
• H5N1 influenza virus stability and transmission risk in raw milk and cheese(Nature Medicine)
• Hundreds of U.S. students quarantined amid measles outbreaks (NBC News)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Measles (CDC Measles (Rubeola))
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: clift notes (CDC FluView)
• Japan sees early flu activity, with school closures(CIDRAP)
• Japan Declares Nationwide Flu Outbreak Following Early Surge in Cases (insightscare)
• ACIP Recommendations Summary (CDC: Influenza)
• American Academy of Pediatrics
• Flu and Children (CDC: Influenza (flu))
• Effectiveness of influenza vaccination to prevent severe disease (CMI: Clinical Microbiology and Infection)
• Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season(FDA)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Evidence to Recommendations Framework (EtR): RSV Vaccination in Adults Aged 50–59 years (CDC: National Center for Immunization and Respiratory Diseases)
• Efficacy and safety of respiratory syncytial virus vaccines (Cochrane Library)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV)
• Effectiveness of NVX-CoV2373 and BNT162b2 COVID-19 Vaccination in South Korean Adolescents (The Pediatric Infectious Disease Journal)
• Trump gets Covid vaccine and flu shot during second checkup of the year (NBC News)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• Understanding Coverage Options (PAXCESS)
• Pharmacometrics of high-dose ivermectin in early COVID-19 from an open label, randomized, controlled adaptive platform trial (PLATCOV)(eLife)
• Antiviral efficacy of oral ensitrelvir versus oral ritonavir-boosted nirmatrelvir in COVID-19 (PLATCOV) (LANCET: Infectious Diseases)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Nirmatrelvir-Ritonavir and Symptoms in Adults With Postacute Sequelae of SARS-CoV-2 Infection (JAMA Internal Medicine)
• Longitudinal patient-reported outcome trajectories in Long COVID: Findings from the STOP-PASC Clinical Trial (OFID)
• Reaching out to US house representative
• Severe Adverse Reaction to Measles Vaccine Due to Homozygous Mutation in the IFNAR2 Gene: A Case Report and Literature Review (Journal of Clinical Immunology)
• Letters read on TWiV 1262
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV covers a MacArthur Award for Jason McLellan, 2025 Nobel Prizes in Physiology or Medicine, first treatment for Huntington's Disease, structure of an archael dsDNA virus from head to tail, and discovery of a Legionella phage that explains a determinant of human disease.

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Become a patron of TWiV!

• Support science education at MicrobeTV
• Jason McLellan wins MacArthur Award (NPR)
• 2025 Nobel Prizes Physiology or Medicine (Nobel Prizes)
• Huntington Disease treatment (BBC)
• Structure of archaeal tailed virus (Sci Adv)
• Discovery of Legionella phage (Sci Adv)
• Microbe of the Month: Legionella (Trends Micro)
• Letters read on TWiV 1261
• Timestamps by Jolene Ramsey. Thanks!

Alan – Specimen of the last female Great Auk finally identified. Jolene – Ribosome studio on IG Vincent – Greater noctule bats prey on and consume passerines in flight

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello chat about Jane Goodall's death and the Nobel prize in Physiology/Medicine for understanding immune system control before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, if 2 doses of the influenza vaccine are better for protection of first season children, if COVID-19 negatively impacts pregnancy and the unborn child, efficacy of long-acting monoclonal antibody against symptomatic COVID-19, where to find PEMGARDA, how to access and pay for Paxlovid, can you be retreated with Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, long COVID in pediatrics, association of COVID-19 with new-onset vascular dementia and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• Jane Goodall's legacy: three ways she changed science (Nature)
• They understood how the immune system is kept in check (The Nobel Prize)
• Daniel Griffin: The Nobel Prize for Understanding Autoimmune Disease (WNYC: New York Public Radio)
• Kennedy's Ties to Ally Leading Vaccine Lawsuits Raise Ethical Concerns (NY Times)
• Ebola outbreak in southern Congo shows signs of containment with no new cases, WHO reports (AP News)
• Ebola Disease (WHO: African Region)
• Premature baby dies from measles in Alberta as cases throughout province near 2,000(Global News)
• DOH Issues Advisory After Measles Detection in City of Oswego Wastewater (Finger lakes dailynew.com)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Measles (CDC Measles (Rubeola))
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: clift notes (CDC FluView)
• Influenza-Associated Pediatric Deaths — United States, 2024–25 Influenza Season (CDC: MMWR)
• ACIP Recommendations Summary (CDC: Influenza)
• American Academy of Pediatrics
• Flu and Children (CDC: Influenza (flu))
• Comparison of 2 Doses vs 1 Dose in the First Season Children Are Vaccinated Against Influenza (JAMA: Open Network)
• Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Evidence to Recommendations Framework (EtR): RSV Vaccination in Adults Aged 50–59 years (CDC: National Center for Immunization and Respiratory Diseases)
• Efficacy and safety of respiratory syncytial virus vaccines(Cochrane Library)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV)
• Neonatal outcomes among pregnant women with COVID-19 (BMC Pregnancy and Childbirth)
• Safety and Efficacy of Pemivibart, a Long-Acting Monoclonal Antibody, for Prevention of Symptomatic COVID-19 (CID)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• Understanding Coverage Options (PAXCESS)
• Retreatment With Nirmatrelvir/Ritonavir Following Return of COVID-19 Symptoms and SARS-CoV-2 Positivity (CID)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Long COVID associated with SARS-CoV-2 reinfection among children and adolescents in the omicron era (RECOVER-EHR) (LANCET: Infectious Diseases)
• Prevalence and duration of clinical symptoms of pediatric long COVID (Frontiers in Pediatrics)
• COVID-19 infection associated with increased risk of new-onset vascular dementia in adults ≥50 years(NPJ| dementia) Reaching out to US house representative
• Letters read on TWiV 1260
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV reviews experiments to understand infection, pathogenesis, and transmission of avian H5N1 influenza virus in goats, and identification of a cellular receptor for tick-borne encephalitis virus.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

• Support science education at MicrobeTV
• Public trust in science (Nature)
• Culling of H5N1 ostriches in Canada (Science)
• H5N1 in goats (Cell Rep)
• Receptor for tick-borne encephalitis virus (Nature)
• Letters read on TWiV 1259
• Timestamps by Jolene Ramsey. Thanks!

Brianne – Astronomers find clues suggesting Planet Y Alan – A tower of worms wriggles like a single organism Vincent – The EPA Is Ending Greenhouse Gas Data Collection. Who Will Step Up to Fill the Gap?

Jay – Who Killed the Electric Car Douglas – Measles and Polio Down in the Schoolyard – Marsh Family parody

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello chat about the ongoing Ebola outbreak in DRC, increases in screwworm diagnoses, a pertussis death in Mississippi before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, monoclonal antibody therapy against RSV, where to find PEMGARDA, long COVID treatment center, where to go for answers to your long COVID questions, olfactory dysfunction following SARS-CoV-2 infection and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• Ebola Disease (WHO: African Region)
• Mexico sees 32% jump in flesh-eating screwworm cases since August as cases move north (Reuters)
• Pediatric Pertussis Death Reported (Mississippi State Department of Health)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Measles (CDC Measles (Rubeola))
• Measles (CDC: Measles Rubeola)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: cliff notes (CDC FluView)
• Influenza-Associated Pediatric Deaths — United States, 2024–25 Influenza Season (CDC: MMWR)
• ACIP Recommendations Summary (CDC: Influenza)
• Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season(FDA)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Nirsevimab Administration and RSV Hospitalization in the 2024-2025 Season (JAMA: Open Network)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Evidence to Recommendations Framework (EtR): RSV Vaccination in Adults Aged 50–59 years (CDC: National Center for Immunization and Respiratory Diseases)
• Efficacy and safety of respiratory syncytial virus vaccines (Cochrane Library)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Olfactory Dysfunction After SARS-CoV-2 Infection in the RECOVER Adult Cohort (JAMA: Open Network)
• Reaching out to US house representative
• Letters read on TWiV 1258
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

From ESCV 2025, Vincent speaks with Elke Wollants about a project to identify SARS-CoV-2 and other viruses in toilet waste from airplanes.

Guest: Elke Wollants

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

• Support science education at MicrobeTV
• Laboratory for Clinical and Epidemiological Virology (KU Leuven)
• Virologists in Greece (TWiV 1255 from ESCV)
• Airplane wastewater surveillance for pathogens (SSRN)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV explains experiments to create genetically modified chickens that are resistant to avian influenza infection, and discovery of combination antiviral therapy for HTLV-1 infection.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

• Support science education at MicrobeTV
• Creating avian influenza virus resistant chickens (Nat Comm)
• Antiretroviral therapy and apoptosis inhibition for HTLV-1 (Cell)
• HTLV-1 infection (Cleveland Clinic)
• Letters read on TWiV 1257
• Timestamps by Jolene Ramsey. Thanks!

Rich – Chagas Disease, an Endemic Disease in the United States Alan – Archive of molecular biology artifacts ends its long, strange trip at a museum Vincent – The World's Oceans Are Hurtling Toward Breaking Point

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

Vincent travels to Thessaloniki, Greece to attend the 27th meeting of the European Society for Clinical Virology, where he speaks with Pamela Vallely, ESCV President, and Piotr Kramarz, Chief Scientist, European CDC, about the activities of ESCV and ECDC.

Guests: Piotr Kramarz and Pamela Vallely

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello lament the anti-vaccine, anti-science composition of the ACIP, US cases of Chagas disease, the Ebola vaccination campaign in the DRC, the death of an infant in LA due to measles complications (SSPE), before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, use of monoclonal antibodies against influenza, the lack of adverse effects of the COVID-19 mRNA in both non-pregnant and pregnant women, where to find PEMGARDA, long COVID treatment center, where to go for answers to your long COVID questions, immune cell infiltration into the central nervous system during long COVID and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• Northeast US states form health alliance in response to federal vaccine limits (Reuters)
• MEETING OF THE ADVISORY COMMITTEE ON IMMUNIZATION PRACTICES (ACIP) (CDC: ACIP)
• Viewpoint: Four tips for understanding this week's ACIP meeting (CIDRAP)
• From Data to Decisions: The Evidence Base for 2025 Fall/Winter Immunizations (CIDRAP)
• Viewpoint: Four tips for understanding this week's ACIP meeting (CIDRAP)
• Vaccine Integrity Project (CIDRAP)
• Chagas Disease, an Endemic Disease in the United States (CDC: Emerging Infectious Diseases)
• Ebola vaccination begins in the Democratic Republic of the Congo (WHO: Democratic Republic of Congo)
• Ebola Disease (WHO: African Region)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• L.A. child dies from complication of measles infection contracted in infancy (LA Times)
• Tracking County-Level Measles Cases in the US (JAMA)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Measles (CDC Measles (Rubeola))
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: clift notes (CDC FluView)
• Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA)
• Efficacy of Baloxavir Treatment in Preventing Transmission of Influenza (NEJM)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Evidence to Recommendations Framework (EtR): RSV Vaccination in Adults Aged 50–59 years (CDC: National Center for Immunization and Respiratory Diseases)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV)
• Moderna Announces Updated COVID-19 Vaccine Against LP.8.1 Variant Generates Strong Immune Response in Humans (Access Newswire)
• Adverse events associated with COVID-19 vaccination or diagnosis among pregnant and non-pregnant women in the United States, 2021-2022 (International Journal of Infectious Diseases)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• PAXLOVID-nirmatrelvir and ritonavir : highlights of prescribing information (Pfizer)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer)
• PAXCESSTM offers access and affordability options to patients prescribed PAXLOVIDTM (nirmatrelvir tablets; ritonavir tablets) (PAXCESS)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• CSF immune cell alterations in women with neuropsychiatric Long COVID (JID)
• Reaching out to US house representative
• Letters read on TWiV 1254
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

Vincent travels to Waterville Valley, NH to attend the Harvard virology retreat, where he speaks with Aaron Schmidt, Ben Gewurz, and Tatum Sass about their careers and their research on influenza virus, Epstein-Barr virus, and CAR-T cells.

Guests: Aaron Schmidt, Ben Gewurz, and Tatum Sass

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• Support science education at MicrobeTV
• Harvard Program in Virology
• Conserved sites on H1 and H3 HA (Sci Adv)
• Antigenic drift expands viral escape (Immunity)
• EBV LMP1 drives B cell oncometabolism (PLoS Path)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello discuss the continued Legionnaire's outbreak in Harlem, invasive Asia longhorned tick and associated disease, potential Ebola outbreak in the Congo, Florida ending childhood vaccine mandates, before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, SARS-CoV-2 spillover into household/domestic dogs, real data demonstrating the benefits of COVID-19 vaccines, states that increase access to COVID-19 vaccines, effective and availability to PAXLOVID, where to find PEMGARDA, long COVID treatment center, where to go for answers to your long COVID questions, the beginning of numerous long COVID clinical studies and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• Legionnaires' Disease: In Harlem (NYC Health)
• 2 dead, dozens sickened by Legionnaires' disease in Westchester County: Officials (NBC News)
• Invasive longhorned tick found for 1st time in New England (AP News)
• First person bitten by east Asian longhorned tick (AP News)
• Invasive, disease-carrying tick found in Maine, the farthest northeast it has been spotted (AP News)
• Suspected cases rise in DR Congo Ebola outbreak (CIDRAP)
• Ebola in the Democratic Republic of the Congo (CDC: Travelers' Health)
• Patricia Mazzei (NY Times)
• Florida Moves to End Vaccine Mandates for Schoolchildren (NY Times)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Measles (CDC Measles (Rubeola))
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• Influenza-Associated Hospitalizations During a High Severity Season — Influenza Hospitalization Surveillance Network, United States, 2024–25 Influenza Season (CDC: MMWR)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: clift notes (CDC FluView)
• Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Risk factors for severe outcomes of respiratory syncytial virus infection in children (LANCET: Regional Health Europe)
• US respiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Evidence to Recommendations Framework (EtR): RSV Vaccination in Adults Aged 50–59 years (CDC: National Center for Immunization and Respiratory Diseases)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV)
• Spillover of SARS-CoV-2 to domestic dogs in COVID-19–positive households: A one health surveillance study (Virus Research)
• Pfizer and BioNTech Announce Topline Data Demonstrating Robust Immune Response With Their LP.8.1-Adapted COVID-19 Vaccine 2025-2026 Formula (Pfizer)
• Minnesota, New York issue executive orders promoting access to COVID vaccines (CIDRAP)
• No. 52: Declaring a Disaster in the State of New York Due to Federal Actions Related to Vaccine Access(NY State: Executive Order #52)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Patient-Reported Outcomes of Nirmatrelvir Treatment for High-Risk, Nonhospitalized Adults With Symptomatic COVID-19 (OFID)
• Real-world effectiveness of nirmatrelvir-ritonavir against severe outcomes of COVID-19 in Taiwan (OFID)
• PAXLOVID-nirmatrelvir and ritonavir : highlights of prescribing information (Pfizer)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer)
• PAXCESSTM offers access and affordability options to patients prescribed PAXLOVIDTM (nirmatrelvir tablets; ritonavir tablets) (PAXCESS)
• Steroids,dexamethasone at the right time (OFID)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Clinical trials explore how Low-Dose Naltrexone could help people with Long COVID (The Sick Times)
• Three clinical trials for Long COVID are testing JAK inhibitors to treat immune dysregulation (The Sick Times)
• Research updates, July 29: Stellate ganglion blocks, may help reduce the severity of some symptoms of Long COVID and ME (The Sick Times)
• New Long COVID and complex disease center at Mount Sinai set to be a leader in research, clinical care (The Sick Times)
• RECOVER-TLC announces new Long COVID clinical trials, receives mixed reactions from patient community (The Sick Times)
• Reaching out to US house representative
• Letters read on TWiV 1252
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV re-issues our 100th episode which featured a discussion of viruses with David Baltimore, an exemplary scientist and Vincent's exemplary mentor, who passed on 6 September 2025.

Guest: David Baltimore

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• Support science education at MicrobeTV
• David's early papers on poliovirus and mengovirus RNA synthesis
• Reverse transcriptase found by Baltimore and Temin (pdfs)
• Nobel Prize in Physiology or Medicine 1975
• The David Baltimore asteroid belt
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV reviews a study showing that the 2009 influenza pandemic virus disrupted biennial respiratory syncytial virus epidemics in northern Stockholm, and development of broad-spectrum synthetic carbohydrate receptors that inhibit viral entry of coronaviruses, filoviruses, and paramyxoviruses.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

• Support science education at MicrobeTV
• Florida will end all state vaccine mandates (Reuters)
• New West Coast Health Alliance (Gov Newsome)
• COVID vaccines to be more accessible in NY State (CBSNews)
• Colorado makes COVID vaccines accessible (Denver Post)
• Massachusetts makes COVID vaccines accessible (Boston dot com)
• Viral interference disrupts RSV biennial pattern (Nat Comm)
• Broad-spectrum antiviral carbohydrate receptors (Science Adv)
• Pedantry about 'in cellulo' (Protocol Online)
• Timestamps by Jolene Ramsey. Thanks!

Angela – Revolutionary Bee "Superfood" Could Save Collapsing Colonies (U Oxford) Kathy – Margaret W. Rossiter, Who Discovered Women of Science, Dies at 81 Rich – Scientists track humpback whale migration with help from AI (Happywhale) Alan – You're probably using the wrong dictionary (Alan's first work of fiction) Vincent – Highly Pathogenic Avian Influenza A(H5N1) Virus Infection in a Child with No Known Exposure

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello is shocked by COVID vaccine restrictions and uncertainties such as pharmacy stock, the ACIP meeting roster and whether it guidance is legal, 3 new ACIP members all anti-vaccine, ending of childhood vaccine mandates in Florida, the continued Legionnaire's outbreak in Harlem, before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, cardia benefits of the influenza vaccine, presence of SARS-CoV-2 antibodies in breast milk following vaccination, the use of antiviral nasal sprays to treat COVID 19, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, where to find PEMGARDA, long COVID treatment center, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• Can You Still Get the Covid Shot? (NY Times)
• Meeting of the Advisory Committee on Immunization Practices (Federal Register)
• Cassidy Calls for Vaccine Committee Meeting to be Postponed Following CDC Departures(US Senate Committee on Health, Education, Labor and Pensions)
• Catherine Stein (Brownstone Institute)
• CIP to review COVID, hep B, and MMRV vaccine recommendations at September meeting (CIDRAP)
• Kennedy plans to add new members to an influential vaccine advisory panel.
• (NY Times)
• Patricia Mazzei (NY Times)
• The Steep Cost of Ron DeSantis's Vaccine Turnabout (NY Times)
• Florida Moves to End Vaccine Mandates for Schoolchildren(NY Times)
• Legionnaires' Disease: In Harlem(NYC Health)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Measles (CDC Measles (Rubeola))
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: clift notes (CDC FluView)
• Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices — United States, 2025–26 Influenza Season (CDC: MMWR)
• ACIP Recommendations Summary (CDC: Influenza (Flu))
• Flu vaccines show benefits for the heart in new studies (CIDRAP)
• Risk of Myocarditis or Pericarditis With High-Dose vs Standard-Dose Influenza Vaccine (JAMA: OPEN)
• High-Dose vs Standard-Dose Influenza Vaccine and Cardiovascular Outcomes in Older Adults (JAMA: Cardiology)
• Influenza vaccination to improve outcomes for patients with acute heart failure (PANDA II) (LANCET)
• Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season(FDA)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Syncytial Virus Immunization Coverage Among Infants Through Receipt of Nirsevimab Monoclonal Antibody or Maternal Vaccination (CDC: MMWR)
• US respiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Evidence to Recommendations Framework (EtR): RSV Vaccination in Adults Aged 50–59 years (CDC: National Center for Immunization and Respiratory Diseases)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (biRxiV)
• SARS-CoV-2 Vaccine-Elicited Antibody Responses in Human Milk (Journal of Pediatric Infectious Diseases Society)
• Interferon-α Nasal Spray Prophylaxis Reduces COVID-19 in Cancer Patients: A Randomized, Double-Blinded, Placebo-Controlled Trial (CID)
• Azelastine Nasal Spray for Prevention of SARS-CoV-2 Infections (JAMA Internal Medicine)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Effect of Metformin on the Risk of Post-coronavirus Disease 2019 Condition Among Individuals With Overweight or Obese (CID)
• Paxlovid (Pfizer)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Steroids,dexamethasone at the right time (OFID)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia: Columbia University Irving Medical Center)
• The answers: Long COVID
• Reaching out to US house representative Florida moves to kill vaccine mandates; state surgeon general slams them as 'slavery' (Herald-Tribune)
• Letters read on TWiV 1250
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV reviews the major shakeup in CDC leadership, herpes simplex virus infection doubles the risk of dementia, and the prototypic crAssphage is a linear phage-plasmid.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

• Support science education at MicrobeTV
• CDC director ousted? (CNN)
• Herpes simplex infection doubles risk of dementia (J Alzheimers Res)
• Fishing for viruses in senile (TWiV 519)
• Epstein-Barr virus and MS (TWiV 869)
• Taking a shot at dementia (TWiV 1207)
• crAssphage is linear phage-plasmid (Cell Host Microbe)
• Crassvirales (MDPI)
• Timestamps by Jolene Ramsey. Thanks!

Brianne – Research posts on Bluesky are more original — and get better engagement Rich – Rabbits With Hornlike Growths Are Hopping Around Colorado. Are They OK? (Wiki on Shope papilloma virus) Jolene – Lessons Learned: Stories from Women Leaders in STEM Vincent – What Makes This Song Great? "Smells Like Teen Spirit" Nirvana

Lori – Tolga bat hospital Emmett – An author recommendation: Peter Watts

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello are dismayed about the recent attack on public health the firing of the director of the CDC as well as resignation of 3 others members of the agency's leadership, the continued Legionnaire's outbreak in Harlem, suspension of Ixchiq the Chikungunya virus attenuated infectious vaccine, the first US case of New World screwworm before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, association Guillian-Barré syndrome with RSV vaccination, guidelines for using RSV vaccines, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, the American College Obstetricians and Gynecologists recommendations for the COVID, RSV and influenza vaccines, FDA approval letters for Pfizer, moderna and Novagax COVID vaccines including label changes for use in those between 5 through 64 years, where to find PEMGARDA, long COVID treatment center, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• White House Says New C.D.C. Director Is Fired, but She Refuses to Leave (NY Times)
• CDC director refuses to leave after White House order (BBC)
• Legionnaires' Disease: In Harlem(NYC Health)
• New York City Health Department Provides Update on Community Cluster of Legionnaires' Disease in Central Harlem(NYC Health: Promoting and protecting the City's health)
• FDA Update on the Safety of Ixchiq (Chikungunya Vaccine, Live) (FDA)
• Vimkunya (Bavarian Nordiac)
• U.S. and Panama for the control of the Screwworm pest (COPEG)
• Rare human case of flesh-eating parasite New World screwworm identified in US(CNN)
• USDA Announces Sweeping Plans to Protect the United States from New World Screwworm (USDA)
• HHS details New World screwworm response after human case(CIDRAP)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Measles (CDC Measles (Rubeola))
• Measles vaccine recommendations from NYP (jpg)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: clift notes (CDC FluView)
• Relative effectiveness of high-dose versus standard-dose influenza vaccine against hospitalizations and mortality according to frailty score (JID)
• FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• ENFLONSIA: novel drug approvals 2025 (FDA)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Evaluation of Guillain-Barré Syndrome (GBS) following Respiratory Syncytial Virus (RSV) Vaccination Among Adults 65 Years and Older (FDA)
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Evidence to Recommendations Framework (EtR): RSV Vaccination in Adults Aged 50–59 years (CDC: National Center for Immunization and Respiratory Diseases)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV)
• Veering from CDC, ACOG recommends maternal vaccination against COVID-19 (CIDRAP)
• ACOG Releases Updated Maternal Immunization Guidance for COVID-19, Influenza, and RSV (American College of Obstericians and Gynecologists)
• COVID-19 Vaccination Considerations for Obstetric–Gynecologic Care (American College of Obstericians and Gynecologists)
• Pfizer and BioNTech's COMIRNATY® Receives U.S. FDA Approval for Adults 65 and Older and Individuals Ages 5 through 64 at Increased Risk for Severe COVID-19 (Pfizer)
• COMIRNATY approval letter (FDA)
• Moderna Receives U.S. FDA Approval for Updated COVID-19 Vaccines Targeting LP.8.1 Variant of SARS-CoV-2 (FEEDS)
• SPIKEVAX approval letter (FDA)
• Novavax's Nuvaxovid 2025-2026 Formula COVID-19 Vaccine Approved in the U.S (Novavax)
• NUVAXOVID approval letter (FDA)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Paxlovid (Pfizer)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Steroids,dexamethasone at the right time (OFID)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Reaching out to US house representative
• Letters read on TWiV 1248
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

Stanley Plotkin joins TWiV to recount his career as a vaccinologist, having participated in the development of vaccines for polio, rabies, and rubella, and his thoughts on the current anti-science, anti-public health, and anti-vaccine climate.

Guest: Stanley A. Plotkin

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

• Support science education at MicrobeTV
• Stanley Plotkin (History of Vaccines)
• Talking about vaccines with Dr. Plotkin (CHOP)
• Path to eradication of rubella (Vaccine)
• Status of cytomegalovirus vaccine (J Inf Dis)
• Human diploid cell vaccines (Dev Biol Stand)
• IPV an essential part of polio eradication (Clin Inf Dis)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello discusses outbreaks of Vibrio vulnificus and Legionnaire's disease in Harlem, the role of the American Association of Pediatrics defining immunization practices, before Dr. Griffin deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, effective of the high and low does influenza vaccines, association Gullian-Barre syndrome with RSV vaccination, guidelines for using RSV vaccines, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, where to find PEMGARDA, long COVID treatment center, where to go for answers to your long COVID questions, vascular aging after COVID-19 and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• Department of Public Health alerts public to rare Vibrio vulnificus bacteria in coastal waters (Mass.gov)
• Legionnaires' Disease: In Harlem (NYC Health)
• Ivermectin to Control Malaria (NEJM)
• AAP has been leading voice on childhood vaccine recommendations since 1930s
• (American Academy of Pediatrics)
• The American Academy of Pediatrics Releases Its Own Evidence-Based Immunization Schedule (American Academy of Pediatrics)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Weekly measles and rubella monitoring (Government of Canada)
• Health Ministry says unvaccinated 18-month-old dies of measles (Times of Israel)
• Ten countries in the Americas report measles outbreaks in 2025 (PAHO: Pan American Health Organization)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles vaccine recommendations from NYP (jpg)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Measles (CDC Measles (Rubeola))
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: clift notes (CDC FluView)
• Relative effectiveness of high-dose versus standard-dose influenza vaccine against hospitalizations and mortality according to frailty score (JID)
• FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• ENFLONSIA: novel drug approvals 2025 (FDA)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Evaluation of Guillain-Barré Syndrome (GBS) following Respiratory Syncytial Virus (RSV) Vaccination Among Adults 65 Years and Older (FDA)
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Evidence to Recommendations Framework (EtR): RSV Vaccination in Adults Aged 50–59 years (CDC: National Center for Immunization and Respiratory Diseases)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (biRxiV)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Paxlovid (Pfizer)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Steroids,dexamethasone at the right time (OFID)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Accelerated vascular ageing after COVID-19 infection: the CARTESIAN study (European Heart Journal)
• Reaching out to US house representative
• Letters read on TWiV 1246
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV reviews fradulent science becoming an industry, FDA may not authorize Pfizer COVID vaccine for young kids, Kennedy won't push strict pesticide regulations conserved betacoronavirus sequences recognized by human T cells, and Bispecific antibodies protect against herpes recurrent disease.

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• Support science education at MicrobeTV
• Frontiers in Comparative Systems Virology
• Fradulent science becomes an industry (Science)
• FDA may not authorize Pfizer COVID vaccine for young kids (CIDRAP)
• Kennedy Won't Push Strict Pesticide Regulations (NY Times)
• Conserved betacoronavirus sequences recognized by human T cells (Cell)
• Bispecific antibodies protect against herpes recurrent disease (Cell Rep)
• Letters read on TWiV 1245
• Timestamps by Jolene Ramsey. Thanks!

Brianne – New Study Suggests Using AI Made Doctors Less Skilled at Spotting Cancer Alan – Save the Microbes effort gets off the ground Vincent – Dr. Vinay Prasad's Catch-22: The Only Way He Can Truly Succeed at His Job is to Get Fired Again

Chaim – "Virus Hunters" by Greer Williams Bridget – Wave Life Sciences and their potential treatment for Alpha-1 antitrypsin deficiency

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello discusses Vijay Prasad's return to the FDA, revoking of COVID vaccine authorization for young children, the Legionnaires' outbreak in Harlem, the new labeling requirements for Ixchiq, the infectious attenuated Chikungunya vaccine and the importation of H5 influenza virus in Antarctica, before Dr. Griffin deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, guidelines for treating COVID-19, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, where to find PEMGARDA, long COVID treatment center, where to go for answers to your long COVID questions, the association of "virus rebound" and post-acute sequelae among hospitalized patients, how virus infection particularly influenza and SARS-CoV-2 may 're-activate' dormant cancer cells and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• Prasad returns to the FDA (Washington Post)
• Pfizer Covid vaccine for young children may not be renewed by FDA (The Guardian)
• Report suggests FDA may not reauthorize Pfizer COVID vaccine for young kids (CIDRAP)
• Factors Associated With Pediatric COVID-19 Mortality: A Pediatric Investigators Collaborative Network on Infections in Canada (PICNIC) Study (Journal of Pediatric Infectious Diseases Society)
• Legionnaires' Disease: In Harlem (NYC Health)
• Recommended Pause in Use of Ixchiq (Chikungunya Vaccine, Live) in Individuals 60 Years of Age and Older While Postmarketing Safety Reports are Investigated (FDA)
• FDA Removes Recommended Pause in Use and Approves Required Updated Labeling (FDA)
• Chikungunya Vaccines (CDC: Chikungunya virus)
• Chikungunya in China (CDC: Travelers' Health)
• Travelers' health notices (CDC: Travelers' Health)
• Areas at Risk for Chikungunya (CDC: Chikungunya virus)
• Adjuvanted recombinant zoster vaccine is effective against herpes zoster ophthalmicus, and is associated with lower risk of acute myocardial infarction and stroke in adults aged ≥50 years (CID)
• Tracking HPAIV H5 through a geographic survey of Antarctic seabird populations
• (Scientific Reports)
• Report details first suspected H5 avian flu detections in seabirds in Antarctica(CIDRAP)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Measles (CDC Measles (Rubeola))
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: clift notes (CDC FluView)
• FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• ENFLONSIA: novel drug approvals 2025 (FDA)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• 2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19: Pemivibart for Pre-exposure Prophylaxis, Vilobelimab for Critical Illness, and Abatacept or Infliximab for Severe or Critical Illness (CID)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Paxlovid (Pfizer)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Steroids,dexamethasone at the right time (OFID)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• TWiV 1243: Capitalism, COVID and Cancer (MicrobeTV)
• Respiratory viral infections awaken metastatic breast cancer cells in lungs(Nature)
• Reaching out to US house representative
• Letters read on TWiV 1244
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV discusses the latest worrisome Executive Order on oversight of federal grantmaking, RFK Jr winds down mRNA viral vaccine development, Lenacapavir, a drug for AIDS prevention and treatment, and how respiratory virus infections awaken dormant metastatic breast cancer cells in lungs.

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• Support science education at MicrobeTV
• Oversight of Federal grantmaking (Whitehouse.gov)
• Grantmaking gets a Christofascist (Rasmussen Retorts)
• HHS winds down mRNA vaccine development (HHS)
• Lives saved by COVID vaccines (JAMA)
• Lenacapavir review (Bicochem Pharm)
• UNAIDS urges Gilead to lower price of lenacapavir (UNAIDS)
• Gilead and price gouging (Wikipedia)
• Respiratory virus infections awaken metastatic breast cancer (Nature)
• Letters read on TWiV 1243
• Timestamps by Jolene Ramsey. Thanks!

Brianne – Xkcd: Geologic Periods Rich – Old Man's War by John Scalzi Alan – The Broken Earth trilogy by N. K. Jemisin Vincent – Cacio e pepe: Good Food pasta recipe sparks fury in Italy

Linda – DNA captured in air could identify life forms

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello re-address the dangers of drinking raw milk, the Legionnaire's outbreak in Harlem and results of a vaccine knowledge survey done by emergency departments before Dr. Griffin deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, reports of influenza-associated acute necrotizing encephalopathy or neuropsychiatric events in children, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, the effectiveness of Pfizer and MODERNA vaccines against the JN.1 variant, risk of children developing severe disease from SARS-CoV-2 infection, where to find PEMGARDA, long COVID treatment center, where to go for answers to your long COVID questions, the association of "virus rebound" and post-acute sequelae among hospitalized patients, effectiveness of COVID-19 vaccines against long COVID, predictors for distinct COVID-19 sequelae including immune disturbances and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• Florida Department of Health Provides Update on Raw Milk(Florida Health)
• Raw milk linked to 21 E coli, Campylobacter infections in Florida (CIDRAP)
• Legionnaires' Disease: In Harlem (NYC Health)
• NYC health officials report Harlem Legionnaires' outbreak(CIDRAP)
• Emergency Department Survey of Vaccination Knowledge, Vaccination Coverage, and Willingness to Receive Vaccines in an Emergency Department Among Underserved Populations (CDC: MMWR)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola) Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Measles (CDC Measles (Rubeola))
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: clift notes (CDC FluView)
• Influenza-Associated Acute Necrotizing Encephalopathy in US Children (JAMA)
• Influenza With and Without Oseltamivir Treatment and Neuropsychiatric Events Among Children and Adolescents(JAMA Neurology)
• FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• ENFLONSIA: novel drug approvals 2025 (FDA)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV)
• Effectiveness of the BNT162b2 and mRNA-1273 JN.1-adapted vaccines against COVID-19-associated hospitalisation and death: a Danish, nationwide, register-based, cohort study (LANCET: Infectious Diseases)
• Hospitalization for COVID-19 and Risk Factors for Severe Disease Among Children: 2022–2024 (Pediatrics)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Metformin and Time to Sustained Recovery in Adults With COVID-19 (JAMA Internal Medicine)
• Drug interaction checker (University of Liverpool)
• Paxlovid (Pfizer)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• SARS-CoV-2 rebound and post-acute mortality and hospitalization among patients admitted with COVID-19(Nature Communications)
• Steroids,dexamethasone at the right time (OFID)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Effectiveness of COVID-19 vaccines against post COVID-19 condition/long COVID (CMI: Clinical Microbiology and Infection)
• Precision Symptom Phenotyping Identifies Early Clinical and Proteomic Predictors of Distinct COVID-19 Sequelae (JID)
• Systemic and SARS-CoV-2 specific Immune Disturbances in Individuals With Post–COVID Syndrome (JID)
• Reaching out to US house representative
• Letters read on TWiV 1242
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV reports the administration putting a choke hold on billions of NIH health research funding, US Senators tell scientists they want to protect the NIH budget, then review a classic experiment showing the mechanism of DNA replication, and explain how jumbo phage DNA is transcribed in a membrane-bound compartment before transfer into proteinaceous "nucleus" compartment.

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• Support science education at MicrobeTV 5:13
• Chokehold on billions in NIH funding (WSJ)
• Senators want to protect NIH budget (Nature)
• Replication of DNA in E. coli (PNAS)
• Biography of Franklin Stahl (DNA Learning Center)
• Franklin Stahl, 95 (Caltech Magazine)
• FW Stahl dies (NY Times)
• Requiem for a machine (Small Things Considered)
• Membrane and protein bound organelles during phage infection (Cell Host Micr)
• Letters read on TWiV 1241
• Timestamps by Jolene Ramsey. Thanks!

Angela – Benefits of interacting with Nature Brianne – "Why Trust Science" Essay Kathy – Dental floss delivery of vaccines to mice Rich – The Monk in the Garden Jolene – JWST COSMOS-Web Interactive Map viewer Vincent – New Injectable Recommended by Europe for HIV Prevention

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello chat about the recent Salmonella typhimurim outbreak, the ousting of another CBER director, confirmation of a new CDC director and results of a recent pool about vaccine safety and trust before Dr. Griffin deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, a new anti-influenza antibody that can be combined with neuraminidase inhibitors, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, the effectiveness of Sinopharm's COVID-19 vaccine, where to find PEMGARDA, safety of the JN.1 updated vaccine, long COVID treatment center, where to go for answers to your long COVID questions, the prevalence of cardiac and pulmonary abnormalities found via medical imaging following COVID-19 and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• Outbreak of Salmonella Typhimurium Infections Linked to Commercially Distributed Raw Milk (CDC: MMWR)
• Top F.D.A. Official Resigns UnderPressure (NY Times)
• In a first, the Senate confirms a new CDC director (NPR)
• KFF Tracking Poll on Health Information and Trust: Vaccine Safety and Trust (KFF)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles vaccine recommendations from NYP (jpg)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Measles (CDC Measles (Rubeola))
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: clift notes (CDC FluView)
• Effects of baloxavir marboxil plus neuraminidase inhibitor versus neuraminidase inhibitor in high-risk patients hospitalized with severe influenza: a post hoc analysis of the Flagstone trial (OFID)
• FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• ENFLONSIA: novel drug approvals 2025 (FDA)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV)
• Safety of JN.1-Updated mRNA COVID-19Vaccines (JAMA)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Paxlovid (Pfizer)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Steroids,dexamethasone at the right time (OFID)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Prevalence of Persistent Cardiovascular and Pulmonary Abnormalities on PET/MRI and DECT Imaging in Long COVID Patients (Journal of Nuclear Medicine)
• Reaching out to US house representative
• Letters read on TWiV 1240
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

TWiV explains a cohort study of over one million Danish children which shows no evidence supporting an increased risk for autoimmune, atopic or allergic, or neurodevelopmental disorders associated with early childhood exposure to vaccines with aluminum-base adjuvants, and a study of antibodies induced by mRNA-1273 and NVX-CoV2373 COVID-19 vaccines which show that polyclonal antibodies against a single site on the spike N-terminal domain show immunodominance, high diversity, and limited cross-reactivity, indicating the need to direct antibody responses away from this site.

Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

• Support science education at MicrobeTV
• No chronic effects of aluminum-based adjuvants in vaccines (Ann Int Med)
• Aluminum in vaccines (CHOP)
• Structural serology of antibody responses to COVID vaccines (Cell Rep)
• Letters read on TWiV 1239
• Timestamps by Jolene Ramsey. Thanks!

Brianne – MHC Class I Antigen Presentation Video Alan – We Become What We Behold Vincent – New Injectable Recommended by Europe for HIV Prevention

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello chat about how flies and milk-snatching might contribute to influenza virus H5N1 among dairy cattle, the recent pertussis oubreak and measles epidemic before Dr. Griffin discusses monoclonal antibody therapy can enrich for RSV variants before deep diving into recent statistics on RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan dashboard, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, the effectiveness of Sinopharm's COVID-19 vaccine, where to find PEMGARDA, provides information for Columbia University Irving Medical Center's long COVID treatment center, where to go for answers to your long COVID questions, how mast cell activation can enhance long COVID and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• Flies, 'milk snatching' among H5N1 transmission contributors in dairy cattle(CIDRAP)
• H5N1 virus invades the mammary glands of dairy cattle through "mouth-to-teat" transmission (NSR: National Science Review)
• Mississippi warns of steep increase in pertussis cases (CIDRAP)
• MSDH Issues Pertussis Alert (Mississippi State Department of Health)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles vaccine recommendations from NYP (jpg)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Measles (CDC Measles (Rubeola))
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: clift notes (CDC FluView)
• FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• ENFLONSIA: novel drug approvals 2025 (FDA)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Respiratory Syncytial virus Strain Evolution and Mutations in Western Australia in the Context of Nirsevimab Prophylaxis (OFID)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (biRxiV)
• Real-world Evaluation of the Effectiveness of Sinopharm COVID-19 Vaccine Against Symptomatic COVID-19 in an Omicron-Dominant Setting in Mozambique (CID)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Paxlovid (Pfizer)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Steroids, dexamethasone at the right time (OFID)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Mast cell activation symptoms are prevalent in Long-COVID (International Journal of Infectious Diseases)
• Using the Right Criteria for MCAS (Current Allergy and Asthma Reports)
• Utility of glucagon-like-peptide-1-receptor agonists in mast cell activation syndrome (The American Journal of the Medical Sciences)
• Reaching out to US house representative
• Letters read on TWiV 1238
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

From the 2025 annual meeting of the American Society for Virology, Charlie Rice, 2020 Nobel Laureate in Physiology or Medicine, talks with Vincent and Kathy about his career and the scientific difficulties he and his laboratory encountered in their attempts to achieve replication of hepatitis C virus in cells in culture.

Guest: Charlie Rice

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

• Support science education at MicrobeTV
• 2020 Nobel Prize (Nobel Prizes)
• Hepatitis C human challenge study (Lancet Gastro Hepatol)
• Rat hepacivirus mouse model for hepatitis C (Hepatol)
• Replication of hepatitis C virus in cells in culture (Science)
• Lessons from domestication of HCV (Curr Opin Virol)

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello have a morning chat about the measles epidemic and H5N1 in cows before Dr. Griffin discusses how vaccination associates with reduced dementia risk before deep diving into recent statistics on measles epidemic, RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan dashboard, a potential new influenza antiviral drug, whether or not the NB.1.8.1 variant should be included in the fall 2025 vaccines, immunization recommendations for COVID-19 vaccines, where to find PEMGARDA, provides information for Columbia University Irving Medical Center's long COVID treatment center, where to go for answers to your long COVID questions, associaton of remesdivir administration and long-term sequelae and contacting your federal government representative to stop the assault on science and biomedical research.

Become a patron of TWiV!

• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Measles (CDC Measles (Rubeola))
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Measles vaccine recommendations from NYP (jpg)
• The impact of highly pathogenic avian influenza H5N1 virus infection on dairy cows (Nature)
• Avian flu exacts heavy financial toll on dairy industry, report says(CIDRAP)
• Inherited IFNAR1 deficiency in otherwise healthy patients with adverse reaction to measles and yellow fever live vaccines (Journal of Experimental Medicine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: clift notes (CDC FluView)
• FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• ENFLONSIA: novel drug approvals 2025 (FDA)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Systematic review and expert consensus on the use of long-acting monoclonal antibodies for prevention of respiratory syncytial virus disease: ARMADA (Advancing RSV Management And Disease Awareness) Taskforce (OFID)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• COVID cases likely rising in half of states, CDC estimates(CBS News)
• Estimated COVID-19 Periodicity and Correlation with SARS-CoV-2 Spike Protein S1 Antigenic Diversity, United States (Emerging Infectious Diseases)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• Estimated COVID-19 Periodicity and Correlation with SARS-CoV-2 Spike Protein S1 Antigenic Diversity, United States (Emerging Infectious Diseases)
• SARS-CoV-2 genomes galore (Nextstrain)
• Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (biRxiV)
• This CDC Resignation Should Scare You (Substack: Beyond the Noise)
• ACIP: COVID-19–Associated Hospitalizations — COVID-NET, April 2025 Update (CDC: National Center for Immunization and Respiratory Diseases))
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug treatments for mild or moderate covid-19: systematic review and network meta-analysis (BMJ)
• Drug interaction checker (University of Liverpool)
• Paxlovid (Pfizer)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Extended nirmatrelvir–ritonavir treatment durations for immunocompromised patients with COVID-19 (EPIC-IC) (LANCET: Infectious Diseases)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Steroids, dexamethasone at the right time (OFID)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Invivyd and Leading Researchers Form SPEAR (Spike Protein Elimination and Recovery) Study Group to Assess the Effects of Monoclonal Antibody Therapy for Long COVID and COVID-19 Post-Vaccination Syndrome (INVIVYD)
• Reaching out to US house representative
• Letters read on TWiV 1236
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.

David Barton, Brian Kemp, and Olve Peersen join TWiV to discuss RNA recombination among enteroviruses and its role in foiling poliovirus eradication.

Guests: David Barton, Brian Kempf, and Olve Peersen

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• Support science education at MicrobeTV
• Enterovirus C recombination groups (J Virol)
• Poliovirus polymerase L420 facilitates RNA recombination (J Virol)
• Picornavirus RNA recombination counteracts error catastrophe (J Virol)
• Extended primer grip and picornavirus RNA recombination (J Virol)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello note that history is being rewritten for justification of changes in COVID vaccine guidelines including myocarditis incidence and the Great Barrington Declaration ignoring presentations at the April 2025 ACIP, the response by the medical community to these changed guidelines, before Dr. Griffin discusses how vaccination associates with reduced dementia risk before deep diving into recent statistics on measles epidemic, RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan dashboard, a potential new influenza antiviral durg, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, immunization recommendations for COVID-19 vaccines, where to find PEMGARDA, provides information for Columbia University Irving Medical Center's long COVID treatment center, where to go for answers to your long COVID questions, associaton of remesdivir administration and long-term sequelae and contacting your federal government representative to stop the assault on science and biomedical research.

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• FDA to look again at myocarditis risk from mRNA-based COVID-19 jabs in young men (FirstWord PHARMA)
• Great Barrington Declaration (Great Barrington Declaration)
• Debunking Herd Immunity: A Review of We Want Them Infected (Global Autoimmune Institute
• Scientific consensus on the COVID-19 pandemic (LANCET)
• John Snow, memo vaccines-plus strategy (John Snow Memorandum)
• This CDC Resignation Should Scare You (Substack: Beyond the Noise)
• COVID-19–Associated Hospitalizations — COVID-NET, April 2025 Update (CDC: National Center for Immunization and Respiratory Diseases)
• Leading Medical Professional Societies, Patient Sue HHS, Robert F. Kennedy, Jr. for Unlawful, Unilateral Vaccine Changes (ACP: American College of Physicians)
• Medical groups sue HHS, Kennedy over COVID vaccine policy changes(CIDRAP)
• Lower risk of dementia with AS01-adjuvanted vaccination against shingles and respiratory syncytial virus infections (Vaccines)
• Influenza vaccination reduces dementia risk (Ageing Research Reviews)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• New Mexico announces measles outbreak in a county detention facility(AP News)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles vaccine recommendations from NYP (jpg)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Measles (CDC Measles (Rubeola))
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: clift notes (CDC FluView)
• Cidara Therapeutics Announces Positive Topline Results from its Phase 2b NAVIGATE Trial Evaluating CD388, a Non-Vaccine Preventative of Seasonal Influenza (CIDARA Therapeutics)
• Experimental flu drug may protect better than flu vaccines(CIDRAP)
• FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Readmission Following Respiratory Syncytial Virus Hospitalization among Children
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (biRxiV)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Steroids,dexamethasone at the right time (OFID)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• The answers: Long COVID
• Association of SARS-CoV-2 With Health-related Quality of Life 1 Year After Illness Using Latent Transition Analysis (OFID)
• Remdesivir and risk of multi-systemic long-term sequelae following COVID-19 hospitalisation (CMI: Clinical Microbiology and Infection)
• Reaching out to US house representative
• Letters read on TWiV 1234
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.