TWiV 217: I just flu in and my arms are shot
Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Dickson Despommier
Vincent, Alan, Rich, and Dickson review influenza vaccines.
Links for this episode:- FDA licensed flu vaccines
- Seasonal influenza vaccine distributed
- How flu vaccine strains are selected (one, two)
- WHO report on flu vaccine strain selection (pdf)
- Derek Smith on antigenic mapping
- Salk's 1945 influenza vaccine
- TIV preparation: Fluzone, Agriflu, Fluvirin, Fluarix, Flulaval, Afluria (pdfs)
- LAIV preparation (pdf)
- Efficacy of flu vaccine 2012-13 (MMWR, virology blog)
- Meta-analysis of flu vaccine efficacy (Lancet)
- Two new flu vaccines FDA approved
- Flublok
- Flublok clinical trial
- Pandemrix and narcolepsy (Yahoo, PLoS One, PLoS One)
- CIDRAP analysis of flu vaccines
- Letters read on TWiV 217
Rich - Repoopulate (original article), Robogut (new clinical trial)Alan - WTF, Evolution?Dickson - The Beauty and Benefits of ScienceVincent - Supercomputing modeling of poliovirus
Listener Pick of the WeekBjorn, Marshall, Meaghan - Glass sculptures of Luke Jerram
Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv
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A concise first-pass summary for understanding the episode quickly.
A detailed readable summary organized by chapter or topic.
A navigable map of subjects, topic flow, and suggested chapters.
A comprehensive, source-grounded extraction of the reusable knowledge in an episode.
Reusable atomic knowledge units extracted from the episode.
A comprehensive extraction focused on health practices, protocols, claims, and safety caveats.
A comprehensive extraction focused on opportunities, strategy, markets, and company building.
Scientific findings, mechanisms, studies, hypotheses, and the limits of the evidence discussed.
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A dedicated analysis of warnings, limitations, trade-offs, weak evidence, and uncertainty.