TWiV 246: Pandora, pandemics, and privacy
Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler
Vincent, Alan, Rich, and Kathy discuss the huge Pandoravirus, virologists planning H7N9 gain of function experiments, and limited access to the HeLa cell genome sequence.
Links for this episode:- Pandoraviruses (Science)
- Unlike anything seen before (virology blog)
- H7N9 gain of function experiments planned (Nature, Science)
- Virologists plan H7N9 gain of function experiments (virology blog)
- Creating a deadly virus? Not!! (USA Today)
- HeLa cell genome sequence (Nature)
- NIH Director explains HeLa agreement (Nature)
- HeLa deal (Nature)
- Biospecimen policy (Nature)
- Sequencing HeLa the right way (turbidplaque)
- Skloot on HeLa deal (The Scientist)
- HeLa deal (NY Times, USA Today)
- Picture on Condit's wall (EID)
- Letters read on TWiV 246
- Video of this episode - view below or at YouTube
Kathy - GeoGuesserAlan - From one, many (YouTube)Vincent - Dave Bhella: The Wildy Award Talk (Microbeworld video)Rich - 1981 primitive internet report (YouTube)
Listener Pick of the WeekCN - How the Mind Works by Steven Pinker
Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv
Available Results
Generated results are saved to your library for reuse and search.
Choose Template
Pick the result you want. You can review provider and model before generating.
A concise first-pass summary for understanding the episode quickly.
A comprehensive, source-grounded extraction of the reusable knowledge in an episode.
Scientific findings, mechanisms, studies, hypotheses, and the limits of the evidence discussed.
A dedicated analysis of warnings, limitations, trade-offs, weak evidence, and uncertainty.
Memorable statements and important claims with attribution and source context.
Technologies, AI models, technical methods, capabilities, limitations, and adoption implications.
A concise first-pass summary for understanding the episode quickly.
A detailed readable summary organized by chapter or topic.
A navigable map of subjects, topic flow, and suggested chapters.
A comprehensive, source-grounded extraction of the reusable knowledge in an episode.
Reusable atomic knowledge units extracted from the episode.
A comprehensive extraction focused on health practices, protocols, claims, and safety caveats.
A comprehensive extraction focused on opportunities, strategy, markets, and company building.
Explicit actions, next steps, habits, recommendations, and things to avoid.
A dedicated inventory of concrete resources named in the episode.
A dedicated analysis of warnings, limitations, trade-offs, weak evidence, and uncertainty.
A concise first-pass summary for understanding the episode quickly.
A detailed readable summary organized by chapter or topic.
A navigable map of subjects, topic flow, and suggested chapters.
A comprehensive, source-grounded extraction of the reusable knowledge in an episode.
Reusable atomic knowledge units extracted from the episode.
A comprehensive extraction focused on health practices, protocols, claims, and safety caveats.
A comprehensive extraction focused on opportunities, strategy, markets, and company building.
Scientific findings, mechanisms, studies, hypotheses, and the limits of the evidence discussed.
Technologies, AI models, technical methods, capabilities, limitations, and adoption implications.
Investment theses, assets, catalysts, valuation reasoning, time horizons, and risks.
Chronologies, actors, causes, consequences, turning points, and competing historical interpretations.
Policies, proposals, stakeholders, arguments, implementation constraints, and predicted effects.
Career paths, skills, hiring signals, workplace decisions, transitions, and limitations of the advice.
Behavioral mechanisms, biases, motivation, habits, emotions, interventions, and evidence limitations.
Economic mechanisms, incentives, indicators, market structure, forecasts, and uncertainty.
Leadership principles, team systems, organizational design, culture, feedback, and failure modes.
Audience, positioning, messaging, acquisition, retention, experiments, metrics, and failed approaches.
Teaching methods, learning strategies, practice, feedback, assessment, and effectiveness evidence.
Theses, premises, arguments, objections, values, thought experiments, and unresolved questions.
Communication patterns, conflict, boundaries, expectations, repair methods, and contextual limitations.
Books, papers, authors, courses, and other learning resources mentioned in the episode.
Repeatable methods, frameworks, mental models, processes, and systems.
Explicit actions, next steps, habits, recommendations, and things to avoid.
Memorable statements and important claims with attribution and source context.
A dedicated inventory of concrete resources named in the episode.
A dedicated analysis of warnings, limitations, trade-offs, weak evidence, and uncertainty.