TWiV 819: How to stall a copy machine

This Week in Virology

TWiV explains how remdesivir inhibits the SARS-CoV-2 RNA polymerase: the drug is incorporated into the growing RNA chain and causes synthesis to stall when the drug clashes with an amino acid in the active site.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler

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Links for this episode Weekly Picks

Kathy – Great Lakes Science Center, Cleveland Rich – How to Temporarily Disable Your Keyboard with a Keyboard Shortcut in Windows Alan – How to Make a Slave and Other Essays by Jerald Walker Vincent – A structure for deoxyribose nucleic acid

Listener Picks

Steve – How the immune system actually works Lise – Lise Meitner: A Life in Physics

Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv

More description

TWiV explains how remdesivir inhibits the SARS-CoV-2 RNA polymerase: the drug is incorporated into the growing RNA chain and causes synthesis to stall when the drug clashes with an amino acid in the active site.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler

Subscribe (free): iTunes, Google Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode Weekly Picks

Kathy – Great Lakes Science Center, Cleveland Rich – How to Temporarily Disable Your Keyboard with a Keyboard Shortcut in Windows Alan – How to Make a Slave and Other Essays by Jerald Walker Vincent – A structure for deoxyribose nucleic acid

Listener Picks

Steve – How the immune system actually works Lise – Lise Meitner: A Life in Physics

Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv

2021-10-21 100 min
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