TWiV 606: Evidence-based science and medicine for COVID-19
Daniel Griffin provides his weekly update on the COVID-19 clinical situation, followed by our discussion of tests of an inactivated vaccine, results of serological surveys, an inhibitor of the cell protease needed for virus entry, and answers to listener questions.
Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler
Guest: Daniel Griffin
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Links for this episode- Inactivated SARS-CoV-2 vaccine protects monkeys (bioRxiv)
- Saliva is more sensitve than nasopharyngeal swab (medRxiv)
- NY serological survey results (NY Times)
- FDA caveats on serological tests (FDA)
- Federal guidelines on when to open
- When to open: Roadmap, blog, video explainer
- Blocking TMPRSS2 blocks SARS-CoV-2 infection (Cell)
- Lawmakers want human challenge studies (Science)
- Letters read on TWiV 606
- Image credit
- Timestamps by Jolene. Thanks!
Intro music is by Ronald Jenkees.
Send your virology questions and comments to twiv@microbe.tv
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A comprehensive extraction focused on health practices, protocols, claims, and safety caveats.
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A dedicated analysis of warnings, limitations, trade-offs, weak evidence, and uncertainty.
A concise first-pass summary for understanding the episode quickly.
A detailed readable summary organized by chapter or topic.
A navigable map of subjects, topic flow, and suggested chapters.
A comprehensive, source-grounded extraction of the reusable knowledge in an episode.
Reusable atomic knowledge units extracted from the episode.
A comprehensive extraction focused on health practices, protocols, claims, and safety caveats.
A comprehensive extraction focused on opportunities, strategy, markets, and company building.
Scientific findings, mechanisms, studies, hypotheses, and the limits of the evidence discussed.
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A dedicated inventory of concrete resources named in the episode.
A dedicated analysis of warnings, limitations, trade-offs, weak evidence, and uncertainty.