The Dr. Hyman Show

Sleep is not just a luxury—it’s a foundational pillar of health that influences nearly every aspect of our well-being. Sleep deprivation doesn’t just cause fatigue; it disrupts hormones, drives inflammation, damages metabolism, and accelerates aging. From the gut microbiome to stress hormones like cortisol, sleep is deeply intertwined with brain, immune, and metabolic health. Yet our modern world—filled with late-night screens, ultra-processed foods, and chronic stress—works against quality rest. 

In this episode, I discuss, along with Dr. Matt Walker and Shawn Stevenson, why we need to address sleep as a core health priority to unlock healing, prevention of chronic disease, and renewed vitality.

Matthew Walker earned his PhD in neuroscience from the Medical Research Council in the UK, and subsequently became a Professor of Psychiatry at Harvard Medical School. He is currently a Professor of Neuroscience and Psychology at the University of California, Berkeley, and director of the Center for Human Sleep Science. Matt’s research focuses on the effect of sleep on human health and disease, brain, and body. He has published more than 100 scientific research studies and has received numerous funding awards from the National Science Foundation and the National Institutes of Health. Matt has given a main-stage TED Talk that has been viewed over 13 million times, has also created several TED Miniseries on sleep, a MasterClass series on sleep, and is author of the New York Times bestseller, Why We Sleep. Matt is also the host of the 5-star-rated, The Matt Walker Podcast.

Shawn Stevenson is the author of the USA Today National bestseller Eat Smarter, and the international bestselling book Sleep Smarter. He’s also the creator of The Model Health Show, featured as the number #1 health podcast in the U.S. with millions of listener downloads each month. A graduate of the University of Missouri–St. Louis, Shawn studied business, biology, and nutritional science and became the cofounder of Advanced Integrative Health Alliance. Shawn has been featured in Forbes, Fast Company, The New York Times, Muscle & Fitness, ABC News, ESPN, and many other major media outlets.

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Full-length episodes can be found here:

How to Optimize Your Sleep with Dr. Matthew Walker

How To Stay Asleep And Sleep More Deeply

Hack Your Sleep

Are U.S. food companies cutting corners at the expense of your health? Vani Hari, known to many as the Food Babe, thinks so—and she’s spent over a decade sounding the alarm. In this episode of The Dr. Hyman Show, she shares why she believes many American products are still made with harmful additives and dyes, even though companies have found ways to remove them in versions sold abroad.

In our conversation, she explains:

• Why she believes Kellogg’s and other U.S. brands aren’t doing enough to protect American consumers.
• The FDA loophole she says allows companies to self-approve food chemicals without oversight.
• How food dyes could be contributing to rising rates of behavioral issues in kids.
• The labeling gaps and industry tactics she says are keeping consumers in the dark.
• How everyday people can push back—and why she believes activism still works.

Don’t miss this insightful episode!

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What if your fatigue, weight gain, hormone imbalances, and brain fog all traced back to a silent disease that affects 1 in 3 people—and you didn’t even know you had it?

In today’s episode, I’m joined by Dr. Elizabeth Boham and Dr. Yousef Elyaman to talk about a condition that’s quietly becoming one of the biggest threats to our health: fatty liver disease—now renamed Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD).

It’s not just a liver issue. It’s deeply connected to heart disease, cancer, infertility, type 2 diabetes, dementia, and even hormone dysfunction. The most alarming part is it’s often missed in traditional medicine because there’s no easy drug to prescribe.

We break down:

• The real root causes—from sugar and starch overload to gut imbalances, toxins, alcohol, and chronic inflammation
• The surprising early warning signs your body might be giving you
• Why standard labs often miss it, and the tests you actually need
• The step-by-step functional medicine approach to reverse fatty liver naturally—using targeted nutrition, lifestyle upgrades, and proven supplements
• 
  

I also share the latest science on inflammation, why it’s the common thread between fatty liver and nearly every chronic disease, and how to calm it down at the root.

This is the episode I wish every patient (and doctor) could hear—because fatty liver is reversible when you catch it early, and the ripple effects of healing it are massive.

If you care about your energy, hormones, brain health, or longevity… this one’s for you.

Dr. Elizabeth Boham is Board Certified in Family Medicine from Albany Medical School, and she is an Institute for Functional Medicine Certified Practitioner and the Medical Director of The UltraWellness Center. Dr. Boham lectures on a variety of topics, including Women’s Health and Breast Cancer Prevention, insulin resistance, heart health, weight control and allergies. She is on the faculty for the Institute for Functional Medicine.

Dr. Yousef Elyaman is the founder and Medical Director of Absolute Health, a primary care functional medicine practice in Ocala, Florida. He is the 100th President of the Marion County Medical Society and the Functional Medicine Director at The Guest House Ocala, a trauma and substance abuse center. Dr. Elyaman also serves as the Medical Director for HumanN, a leading nutraceutical company, and is a Consultant for Quest Diagnostics Laboratory in their Wellness Division. He is teaching Faculty for the Institute for Functional Medicine on their Cardiometabolic module. Dr. Elyaman belongs to the first graduating class of the Institute for Functional Medicine. He is Board-certified in Internal Medicine and holds certifications in functional and integrative medicine as well. His leadership and expertise are reflected in his diverse roles, demonstrating his commitment to advancing medical knowledge and improving patient care. When not at work, Dr. Elyaman loves spending time with his wife and seven children where they live on a cattle and horse ranch.

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How To Prevent And Reverse Fatty Liver Disease with Functional Medicine

The Best Diet to Reverse Fatty Liver Disease with Dr. Yousef Elyaman

Why Fatty Liver Is So Common And How To Heal It

We’re overfed, but undernourished. Despite having access to more food than ever, most people are walking around with nutrient deficiencies that could be accelerating aging, increasing disease risk, and depleting energy levels. That’s why I sat down with Dr. Rhonda Patrick, a leading expert in nutritional science and aging, to break down what we’re missing—and why it matters. In this episode of The Dr. Hyman Show, we explore:

• Why nearly 70% of Americans are deficient in vitamin D and what that means for longevity.
• The overlooked role of magnesium in metabolism, blood sugar, and brain function.
• Why our food system leaves us malnourished—even if we eat a “healthy” diet.
• The best way to assess and correct micronutrient imbalances for optimal health.
• 
  

Your body can’t function properly without the right nutrients. This episode will show you how to fill the gaps and take control of your health.

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Fertility challenges are increasingly linked to lifestyle and environmental factors that go far beyond reproductive organs. Emerging science reveals that metabolic health, inflammation, diet, and exposure to environmental toxins all play a profound role in hormonal balance, egg and sperm quality, and even early embryo development. Key drivers of dysfunction—such as ultra-processed food, insulin resistance, gut imbalances, and mitochondrial damage—are rarely addressed in conventional fertility care, despite their deep impact. Paying attention to these overlooked root causes offers not only a powerful path to improving fertility but also the foundation for lifelong health in both parents and their future children.

In this episode, I discuss, along with Kelly LeVeque, what we can do to improve our fertility, which ultimately impacts the future health of our children.

Kelly LeVeque is a holistic nutritionist, celebrity health coach, the best-selling author of Body Love and Body Love Every Day, and most importantly, mom of three little boys. Kelly LeVeque is passionate about the science of human nutrition and is always guided by a practical and optimistic approach to wellness. Kelly helps clients improve their health, achieve goals, and develop sustainable habits to live a healthy and balanced life. Kelly is a regular contributor to numerous health, wellness, and lifestyle publications.

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Full-length episodes can be found here:

Fertility in Crisis: Exploring the Toxic Threats to Fertility and the Rise in Infertility

The Fertility Crisis: Why it’s Happening and How to Fix it

Boost Fertility Naturally: Top Foods to Eat

What if the key to aging well had been hiding in plain sight—inside our cells, our food, and even… dolphins? That’s exactly what Stephanie Venn-Watson, DVM, a veterinary epidemiologist, discovered while studying dolphins in the U.S. Navy’s marine mammal program. She found that some dolphins were aging significantly slower than others, leading to the discovery of C15:0—a newly recognized essential fatty acid that supports cellular health, fights inflammation, and may even slow the aging process. In this episode of The Dr. Hyman Show, we dive into:

• How studying dolphins led to the discovery of C15:0 as the first essential fatty acid found in 90 years.

• Why a deficiency in this nutrient could be accelerating aging and chronic disease.

• How C15:0 strengthens cell membranes, reduces inflammation, and promotes longevity.

• The connection between diet, metabolic health, and optimal aging.

• What you can do to ensure you’re getting enough of this essential fatty acid.

This groundbreaking discovery could change how we think about nutrition and longevity.

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The connection between mental health and metabolic health is far deeper than once believed, with growing evidence showing a powerful, bidirectional relationship. Inflammation, poor diet, and gut dysfunction are now recognized as key drivers of both physical and psychological illness—often hiding in plain sight. By addressing root causes such as blood sugar imbalances, nutritional deficiencies, and microbiome disruption, many chronic mental health conditions can improve or even resolve. This emerging science challenges the traditional separation of mind and body, pointing instead to an integrated approach where healing the body becomes essential for healing the brain. Recognizing this link is crucial in shifting the future of mental health care.

In this episode, I discuss, along with Dr. Chris Palmer and Dr. Shebani Sethi, why our diet is so closely related to the state of our mental health.

Dr. Chris Palmer is a psychiatrist and researcher working at the interface of metabolism and mental health. He is the Director of the Department of Postgraduate and Continuing Education at McLean Hospital and an Assistant Professor of Psychiatry at Harvard Medical School. For over 25 years, he has held leadership roles in psychiatric education, conducted research, and worked with people who have treatment-resistant mental illnesses. He has been pioneering the use of the medical ketogenic diet in the treatment of psychiatric disorders - conducting research in this area, treating patients, writing, and speaking around the world on this topic. More broadly, he is interested in the roles of metabolism and metabolic interventions on brain health.

Dr. Shebani Sethi is a double board-certified physician in Obesity Medicine and Psychiatry. She is the Founding Director of Stanford University’s Metabolic Psychiatry program and Silicon Valley Metabolic Psychiatry, a new center in the San Francisco Bay Area focused on optimizing brain health by integrating low carb nutrition, comprehensive psychiatric care, and treatment of obesity with associated metabolic disease. 

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Full-length episodes can be found here:

The Hidden Connection Between Gut Health & Mental Health That Therapy and Drugs Cannot Fix

A Harvard Psychiatrist Rethinks Mental Health As A Metabolic Disease

How Does Ultra-Processed Food Affect Our Mental Health?

You probably know Ian Somerhalder from The Vampire Diaries or Lost, but these days, he’s on a mission far bigger than Hollywood. Ian has dedicated his time and platform to tackling some of the most pressing issues of our time—our broken food system, soil depletion, and the health crisis caused by industrial agriculture. In this episode of The Dr. Hyman Show, we explore:

• How Ian’s passion for regenerative agriculture was shaped by his childhood and family history.
• The alarming impact of pesticides on human health and the environment.
• Why farmers are stuck in a toxic cycle—and how regenerative farming offers a way out.
• How shifting just 10% of U.S. farmland to regenerative practices could transform our health and economy.
• The powerful connection between soil health, gut health, and disease prevention.

Ian’s journey proves that real change starts with what’s on our plates. Don’t miss this inspiring conversation.

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The pervasive presence of microplastics and environmental toxins in our daily lives poses a growing threat to human health, with impacts ranging from hormonal disruption and metabolic dysfunction to immune system compromise and chronic inflammation. These contaminants, found in food packaging, water supplies, personal care products, and even the air we breathe, accumulate in the body and contribute to the rise in chronic diseases such as obesity, diabetes, cancer, and autoimmune conditions. Understanding their far-reaching effects is essential, but the good news is that the body has powerful detoxification mechanisms that, when properly supported through dietary choices, lifestyle adjustments, and targeted supplementation, can help mitigate their damage. 

In this episode, I discuss, along with toxin-expert Dr. Joseph Pizzorno, why we need to take action to reduce toxin exposures, reverse existing damage, and build a foundation for long-term well-being.

Dr. Joseph Pizzorno is a transformational leader in medicine. Through half a century of work, he has helped establish and advance the academic, scientific, and clinical protocols for natural, functional, integrative, and environmental medicine. As founding president of Bastyr University in 1978, he coined the term “science-based natural medicine” and led Bastyr to become the first-ever accredited institution in the field. He has set worldwide standards of practice by authoring or co-authoring six textbooks for doctors, including the Textbook of Natural Medicine (over 100,000 copies in 4 languages across 5 editions) and Clinical Environmental Medicine. He is Editor-in-Chief of PubMed-indexed IMCJ—the most widely read, peer-reviewed journal in the field (25,000 copies each issue). He is a founding member of the Board of Directors of the Institute for Functional Medicine, where he served three terms as Chair. A licensed naturopathic physician, educator, researcher, and expert spokesman, he is also the author or co-author of eight consumer books (most recent, Healthy Bones, Healthy You! with his wife Lara). 

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Microplastics: What They Are, Why They are Dangerous, and How to Protect Yourself

Environmental Toxins: How To Eliminate the Silent Killers with Dr. Joseph Pizzorno

How To Reduce Your Environmental Toxin Exposure

What if I told you life insurance companies can predict, almost to the month, when you’re going to die? That’s exactly what Gary Brecka, a human biologist and former mortality expert, used to do—until he uncovered something shocking. After years of analyzing blood work and medical records, he realized that the biggest predictors of disease and early death aren’t genetic—they’re modifiable. Now, he’s using that knowledge to help people optimize their health and extend their lifespan. In this episode of The Dr. Hyman Show, we discuss:

• How insurance companies use hidden health data to predict life expectancy with stunning accuracy.
• The biggest factors that shorten lifespan—and why most of them are within our control.
• Why vitamin deficiencies, especially vitamin D, are quietly fueling chronic disease.
• How the right biohacking tools, like red light therapy and oxygen optimization, can reverse aging.
• What you can do today to take control of your health and longevity.

This conversation will change the way you think about your own health.

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This episode is brought to you by BON CHARGE, Timeline Nutrition, Paleo Valley, and Big Bold Health.

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Our immune system operates like a finely tuned symphony, yet many of us find ourselves out of harmony, vulnerable to persistent infections, autoimmune conditions, and chronic disease. Rather than merely suppressing symptoms, a Functional Medicine approach seeks to identify and address the underlying disruptions driving immune imbalance. Central to this dysfunction is compromised gut health, which undermines immune regulation, while mitochondrial impairment and chronic inflammation further erode the body's capacity for resilience and repair. By restoring balance at the root level, we can cultivate a more robust and adaptive immune system.

In this episode, I discuss, along with Dr. Elroy Vojdani and Dr. Leonard Calabrese, how cleaning up our diets, improving gut health, removing toxins, and decreasing stress can do wonders for our immune systems.

Dr. Elroy Vojdani is a pioneer in the field of functional medicine and research and is the founder of Regenera Medical, a concierge functional medicine practice in Los Angeles, California. He graduated from USC Keck School of Medicine, is a certified Institute for Functional Medicine Practitioner. Dr. Vojdani has conducted medical scientific research for decades with more than 25 publications in multiple peer-reviewed journals. He is also world-renowned for his research and development of state-of-the-art lab testing in the field of immunology. He recently authored a book entitled “When Food Bites Back” which discusses the role of food immune reactions in the development of autoimmune disease. 

Dr. Leonard Calabrese, is an expert in immunology and rheumatology. In fact, he is a Professor of Medicine at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University and Vice Chair of the Department of Rheumatic and Immunologic Diseases. Dr. Calabrese is the director of the RJ Fasenmyer Center for Clinical Immunology at the Cleveland Clinic and holds joint appointments in the Department of Infectious Diseases and the Wellness Institute. Dr. Calabrese has made significant contributions to science in the fields of chronic viral infections and autoimmunity and vascular inflammatory diseases of the brain. He has received numerous awards and honors for his contributions to the advancements of immunology and wellness.

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Boost Your Immunity with These Simple Steps

How To Reset Your Immune System At A Cellular Level

The Secrets to Creating a Healthy Immune System

The modern food industry is built for profit, not health. Ultra-processed foods dominate grocery shelves, fueling the epidemic of obesity, diabetes, and chronic disease. But how did we get here? And what can we do to fix it? In this episode of The Dr. Hyman Show, I sit down with Michael Pollan, award-winning journalist and food activist, to break down the hidden forces shaping our food system and the urgent need for change.

In this powerful conversation, you’ll discover:

• How a handful of corporations control our entire food supply—and why that’s a problem.
• The shocking truth about ultra-processed foods and how they’re engineered to keep you hooked.
• Why our food system collapsed during the pandemic and what it revealed about its fragility.
• How food companies quietly buy up health brands and use misleading labels to keep consumers in the dark.
• The role of policy and lobbying in keeping unhealthy food cheap and widely available.

Make sure to tune in—this is a conversation every American needs to hear.

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With rates of Alzheimer’s and dementia rising steeply, especially among women, the conventional pharmaceutical model has largely failed in treating the brain. Functional Medicine takes a different systems-based, personalized approach—focusing on inflammation, metabolic health, and environmental exposures—which offers real hope for prevention and even reversal of cognitive decline.

In this episode, I discuss, along with Dr. Heather Sandison, Dr. David Perlmutter, and Maria Shriver, why it is possible to reverse cognitive decline and the cutting-edge science of brain health and Alzheimer’s prevention.

Dr. Heather Sandison is the The New York Times bestselling author of Reversing Alzheimer’s The New Toolkit to Improve Cognition and Protect Brain Health. As a renowned naturopathic doctor specializing in neurocognitive medicine, she’s the founder of Solcere Health Clinic, San Diego’s premier brain optimization clinic, and Marama, a residential program turning memory care into memory recovery. Dr. Sandison has dedicated her career to supporting those suffering with dementia and published her most recent clinical findings in the Journal of Alzheimer’s Disease. She’s excited to shatter common misconceptions about Alzheimer’s and share what she’s learned about keeping your brain sharp at any age.

Dr. David Perlmutter is a Board-Certified Neurologist and five-time New York Times bestselling author. He serves on the Board of Directors and is a Fellow of the American College of Nutrition. He is the author of Grain Brain and Drop Acid, among others. Dr. Perlmutter received his M.D. degree from the University of Miami School of Medicine where he was awarded the Leonard G. Rowntree Research Award. He serves as a member of the Editorial Board for the Journal of Alzheimer’s Disease and has published extensively in peer-reviewed scientific journals including Archives of Neurology, Neurosurgery, and The Journal of Applied Nutrition.

Shriver is a bestselling author, award-winning journalist, former First Lady of California, founder of the Women’s Alzheimer’s Movement, and Strategic Advisor on Women’s Health and Alzheimer’s at Cleveland Clinic. Shriver works to use her voice and platforms to advance some of our nation’s most pressing issues affecting women and women’s health. In November 2023, Shriver joined the President and the First Lady to announce the first-ever White House Initiative on Women’s Health Research, an effort led by Dr. Biden and the White House Gender Policy Council, to galvanize the Federal government and the private and philanthropic sectors to spur innovation, unleash transformative investment to close research gaps, and improve women’s health. Shriver’s advocacy led to the establishment of this historic initiative, and she continues to advise and collaborate with Dr. Biden. She is also the co-founder of the brain health and wellness brand MOSH and founder of Shriver Media.

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Full-length episodes can be found here:

How to Reverse Dementia with Dr. Heather Sandison

https://drhyman.com/blogs/content/podcast-ep929?_pos=24&_sid=7873ecf2c&_ss=r

How to Prevent Alzheimer’s with Your Fork

https://drhyman.com/blogs/content/podcast-ep47?_pos=8&_sid=7873ecf2c&_ss=r

Maria Shriver's Journey: Redefining Women's Health and Alzheimer's Prevention

https://drhyman.com/blogs/content/podcast-ep908?_pos=12&_sid=7873ecf2c&_ss=r

Dementia rates are skyrocketing, and cognitive decline is a growing concern. But what if you could actually grow a new brain? In this episode of The Dr. Hyman Show, I sit down with Alberto Villoldo, PhD, a medical anthropologist and shamanic healer (and author of Grow a New Brain), to explore the powerful intersection of ancient wisdom and cutting-edge neuroscience.

In this eye-opening conversation, you’ll discover:

• The Amazonian secret to protecting the brain from dementia and cognitive decline.
• How certain plant compounds can activate your body’s natural detox and repair systems.
• The surprising role of gut health in brain regeneration—and how to reset your microbiome.
• Why serotonin depletion is wreaking havoc on mental health and how to restore balance.
• How shamanic healing and modern science align to create lasting cognitive health.

Tune in to learn how you can take control of your brain health and unlock the potential for true regeneration.

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There is a significant impact of food on brain health and overall well-being, with great importance placed on nutrient-dense, anti-inflammatory foods. Unfortunately, nutrient levels of modern crops are declining, but regenerative agriculture is helping to restore food quality. Specific brain-boosting foods such as leafy greens, small cold-water fish, and polyphenol-rich plants have an ability to reduce neuroinflammation, protect against cognitive decline, and enhance mental clarity. And, ultimately, identifying whole food sources of essential nutrients will support your entire body.

In this episode, I discuss, along with Dr. Jeff Bland and Dr. William Li, practical tips on choosing the most nutrient-dense foods and how to harness their benefits for overall health.

Dr. Jeff Bland is the founder of Big Bold Health, a company on a mission to transform the way people think about one of nature’s greatest innovations—the immune system. Through Big Bold Health, Dr. Bland is advocating for the power of Immuno-Rejuvenation to enhance immunity at a global level, often through the rediscovery of ancient food crops and superfoods. To get there, he is building a network of small farms and suppliers throughout the US that take a clear stance on regenerative agriculture, environmental stewardship, and planetary health. Dr. Bland’s career in health spans more than 40 years. A nutritional biochemist by training, he began in academia as a university professor. He then spent three decades in the natural products industry, working alongside other pioneers. A lifelong educator, Dr. Bland has traveled the world many times over in his role as the “father of functional medicine.” In 1991, he and his wife, Susan, founded The Institute for Functional Medicine. In 2012, he founded another educational nonprofit called the Personalized Lifestyle Medicine Institute. Dr. Bland is the author of The Disease Delusion: Conquering the Causes of Chronic Illness for a Healthier, Longer, and Happier Life, as well as countless additional books and research papers.

Dr. William Li is a world-renowned physician, scientist, speaker, and author of Eat to Beat Disease: The New Science of How Your Body Can Heal Itself. He is best known for leading the Angiogenesis Foundation. His groundbreaking work has impacted more than 70 diseases including cancer, diabetes, blindness, heart disease, and obesity. His TED Talk, Can We Eat to Starve Cancer? has garnered more than 11 million views, and he has appeared on The Dr. Oz Show, Martha Stewart Live, CNN, MSNBC, NPR, Voice of America, and has presented at the Vatican’s Unite to Cure conference. An author of over 100 scientific publications in leading journals such as Science, The New England Journal of Medicine, The Lancet, and more, Dr. Li has served on the faculties of Harvard, Tufts, and Dartmouth Medical School. Find Dr. Li’s Eat To Beat Disease Masterclass at drwilliamli.com/masterclass and get a copy of his book, Eat To Beat Disease at drwilliamli.com/book-li/.

Full length episodes can be found here:

Nourish Your Brain with These Powerful Superfoods

https://drhyman.com/blogs/content/podcast-ep909?_pos=1&_sid=652901034&_ss=r

How The Most Important Superfood You've Never Heard About Will Rejuvenate Your Immune System

https://drhyman.com/blogs/content/podcast-ep176?_pos=10&_sid=652901034&_ss=r

Cancer Can't Stand This Diet: Dr. William Li's Anti-Cancer Nutrition Breakthroughs

https://drhyman.com/blogs/content/podcast-ep890?_pos=4&_sid=ec054bdd0&_ss=r

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Friendship isn’t just a feel-good concept—it’s essential for your health, happiness, and longevity. In this episode of The Doctor’s Farmacy, I sit down with world-renowned author and leadership expert Simon Sinek to explore the science and psychology of friendship—why we need it, how it impacts our biology, and what it takes to build deep, meaningful relationships in an increasingly disconnected world.

In this fascinating conversation, we discuss:

• The surprising link between friendship and physical health—how loneliness drives inflammation, chronic disease, and even early death.
• Why your five closest friends determine your habits, health, and overall well-being.
• The social contagion effect—how behaviors like diet, exercise, and even emotions spread through friend groups.
• Why food, fitness, and lifestyle interventions won’t work unless we also address social health.
• The biggest friendship mistakes people make—and how to fix them.
• The missing conversation in longevity research—why friendship might be the ultimate “biohack.”

If you’ve ever wondered why making friends as an adult feels so hard, or how to create stronger connections in your life, this is an episode you won’t want to miss.

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The rise in obesity and chronic disease over the years is alarming. Rather than genetics, it can be attributed to environmental and dietary changes, emphasizing the role of food quality over quantity. And while GLP-1 agonists like Ozempic may show some promise in addressing metabolic dysfunction, concerns about long-term effects, muscle loss, and cost highlight the need for a more nuanced approach. Ultimately, a holistic strategy that includes diet, lifestyle, and personalized interventions is essential for sustainable health improvements.

In this episode I discuss, along with Dr. Tyna Moore and Calley Means, the complexity of obesity, moving beyond the simplistic "calories in, calories out" model to focus on factors like insulin resistance, ultra-processed foods, and metabolic dysfunction.

With nearly three decades experience in the medical world, Dr Tyna Moore is a leading expert in holistic regenerative medicine and resilient, metabolic health. Traditionally and alternatively trained in science and medicine as both a Naturopathic Physician and Chiropractor, she brings a unique perspective to those wishing to build a more robust foundation in their health and well-being. She is a podcast host, author, speaker, kettlebell devotee and mother. She is a fierce advocate for health autonomy and personal responsibility, which she helps others improve through her many offerings at drtyna.com and on her podcast, The Dr Tyna Show. Her true passion is coaching healthcare practitioners to utilize social media and build the online business of their dreams so they aren’t shackled by illegal mandates and can enjoy more time, money and autonomy.

Calley Means is the founder of TrueMed, a company that enables tax-free spending on food and exercise. He is also the co-author with his sister, Dr. Casey Means, ofGood Energy: The Surprising Connection Between Metabolism and Limitless Health, and is now available for pre-order.Earlier in his career, Calley was a consultant for food and pharma companies and is now exposing practices they use to weaponize our institutions of trust. In the past year, he’s met with 50 members of Congress and presidential candidates advocating policies to combat the corruption of the pharma and food industries. He is a graduate of Stanford and Harvard Business School.

Full length episodes can be found here:

Can Ozempic Fix Our Obesity Crisis

Ozempic: A Weight-Loss Miracle of Metabolic Menace?

The Science of Weight Loss: What You Need to Know

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What if instead of managing diabetes with drugs, we focused on reversing it? In this episode of The Dr. Hyman Show, I sit down with Sami Inkinen, CEO and co-founder of Virta Health, and Dr. Greeshma Shetty, a board-certified endocrinologist, to discuss an approach that’s transforming how we treat metabolic disease. They share groundbreaking research and real-world results that prove type 2 diabetes isn’t a lifelong sentence—it can be reversed with the right nutritional and care model.

In this conversation, you’ll learn:

• Why mainstream medicine still treats type 2 diabetes as a progressive disease—even though science shows it’s reversible.
• How Virta Health is using a combination of nutritional therapy and continuous remote care to achieve Ozempic-level results, without the drugs.
• The critical role of personalized dietary interventions in reversing metabolic dysfunction.
• How a high-touch, tech-driven approach to patient care is leading to long-term success.
• The real cost of diabetes—not just for individuals, but for the entire healthcare system—and why prevention and reversal should be the priority.

If you or someone you love is dealing with type 2 diabetes, this is a must-listen episode.

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Ultra-processed foods (UPFs) are identified as the leading cause of preventable death globally. These foods are chemically altered, stripped of their natural structures, and filled with additives, sugars, unhealthy fats, and preservatives, resulting in products that offer little to no nutritional benefit while contributing significantly to chronic disease.

In this episode, I talk with Vani Hari and Dr. Shebani Sethi about why ultra-processed foods are not just a health risk—they are a public health crisis.

Vani Hari is the food activist behind FoodBabe.com, a NY Times best-selling author of 4 books, founder of the organic products brand Truvani, and was named one of the “Most Influential People on the Internet” by Time magazine. Hari’s viral testimony before the US Senate sparked a massive movement to stop American food companies from poisoning their own citizens with ingredients they don’t use in other countries. Hari founded Food Babe to spread information about what is really in the American food supply. She teaches people how to make the right purchasing decisions at the grocery store, how to live an organic lifestyle, and how to travel healthfully around the world. Vani has gathered hundreds of thousands of petitions to change the food system and influenced how major food giants like Kraft, Subway, Chipotle, Chick-fil-A, and Starbucks create their products, steering them towards more healthful policies.

Dr. Shebani Sethi is a double board-certified physician in Obesity Medicine and Psychiatry. She is the Founding Director of Stanford University’s Metabolic Psychiatry program and Silicon Valley Metabolic Psychiatry, a new center in the San Francisco Bay Area focused on optimizing brain health by integrating low carb nutrition, comprehensive psychiatric care, and treatment of obesity with associated metabolic disease. 

Full length episodes can be found here:

Why the Last Thing that Should Ever Eat is Ultra Processed Foods

How To Be A Food Activist In Your Own Kitchen

How Does Ultra-Processed Food Affect Our Mental Health?

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We all know sleep is important, but most of us don’t realize just how much it shapes our health—from metabolism and heart function to emotional well-being and even social connections. In this episode of The Dr. Hyman Show, I sit down with world-renowned sleep expert Matthew Walker, PhD, to uncover the science behind why sleep is one of the most powerful (and overlooked) tools for longevity.

In this fascinating conversation, we discuss:

• Why Dr. Walker sees sleep as the foundation of good health and how it enhances the benefits of diet and exercise.
• The dramatic effects of even mild sleep deprivation on cognitive function and emotional health.
• How poor sleep can disrupt blood sugar regulation and increase the risk of chronic disease.
• The science behind deep sleep and its role in memory, learning, and brain detoxification.
• Simple, science-backed strategies to improve your sleep quality starting tonight.

If you’ve ever struggled with sleep—or just want to optimize your health—this is an episode you won’t want to miss.

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Highly processed vegetable oils, derived from seeds and beans, have become a dominant part of modern diets despite significant health concerns. Historical biases in nutrition science, influenced by the vegetable oil industry, have promoted these oils despite evidence from controlled studies showing negative health outcomes. These oils are unstable, prone to oxidation, and can create toxic byproducts, particularly when exposed to heat, contributing to inflammation and chronic diseases. Although they can lower LDL cholesterol, studies have shown that this reduction does not necessarily improve heart health and may increase risks for other conditions like cancer. In contrast, traditional fats like extra virgin olive oil and omega-3-rich foods offer more stability and health benefits, emphasizing the need for a balanced, minimally processed approach to dietary fats.

In this episode, I talk with Nina Teicholz and Max Lugavere to explore the health impacts of different types of fats and oils, debunking misconceptions around cooking with extra virgin olive oil and emphasizing the dangers of industrial vegetable oils.

Nina Teicholz is a science journalist and author of the New York Times bestseller, The Big Fat Surprise, which upended the conventional wisdom on dietary fat—especially saturated fat—and spurred a new conversation about whether these fats in fact cause heart disease. She is also the founder of the Nutrition Coalition, a non-profit working to ensure that government nutrition policy is transparent and evidence-based—work for which she’s been asked to testify before the U.S. Department of Agriculture and the Canadian Senate.

Max Lugavere is a health and science journalist and the author of the New York Times best-seller Genius Foods: Become Smarter, Happier, and More Productive While Protecting Your Brain for Life, now published in 10 languages around the globe. His sophomore book, also a best-seller, is called The Genius Life: Heal Your Mind, Strengthen Your Body, and Become Extraordinary and latest book Genius Kitchen. Max is the host of a #1 iTunes health and wellness podcast, called The Genius Life. Max appears regularly on The Dr. Oz Show, The Rachael Ray Show, and The Doctors. He has contributed to Medscape, Vice, Fast Company, CNN, and The Daily Beast, has been featured on NBC Nightly News, The Today Show, and in The New York Times and People Magazine. He is an internationally sought-after speaker and has given talks at South by Southwest, the New York Academy of Sciences, the Biohacker Summit in Stockholm, Sweden, and many others.

Full length episodes can be found here:

Is Vegetable Oil Good or Bad for You?

Nina Teicholz

The Best Diet for Your Brain

This episode is brought to you by BIOptimizers.

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Have you ever wondered if cholesterol-lowering statins are as effective as they claim? In this episode, Dr. Mark Hyman and Dr. Aseem Malhotra reveal the truth about these medications and the pharmaceutical industry’s influence on your health. Discover why lifestyle changes like diet and exercise can be more powerful than pills, and how misleading studies have shaped what we believe about heart health.

In this episode, we discuss:

• Big pharma’s influence on medical research
• The benefits, drawbacks, and misuse of statins
• The Role of Insulin Resistance in Heart Disease
• The Importance of Lifestyle Over Medication
• The Impact of Meditation on Heart Disease

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Our current food system is a national emergency. It’s intricately designed to confuse and mislead consumers, making healthy choices difficult and contributing to America’s chronic disease epidemic. In this episode, I sit down with Senator Cory Booker to delve into the systemic issues impacting our diet, food labeling, and the power of policy change. 

In this episode, we discuss:

• How food packaging is designed to confuse or mislead consumers
• The link between the food system, chronic illness, and the unintended consequences of food policies that increase disease and healthcare costs.
• The harmful effects of ultra-processed foods
• The negative impact of industrial farming practices on the environment, soil health, and the nutritional quality of food
• The importance of personal health advocacy and broader public health initiatives to transform the food system, improve health outcomes, and reduce healthcare costs

Uncover the truth behind our food politics and discover how informed choices can lead to a healthier future. This conversation was hosted by Sixth and I in Washington, DC.

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Do you ever feel like the more meds you take, the worse you feel? The problem might lie in how our healthcare system operates. In this episode, I sit down with Dr. Marty Makary to tackle the alarming rise of colon cancer among young people, explore how our microbiome plays a crucial role in preventing chronic diseases, and discuss the unsettling influence of the pharmaceutical industry on medical practices. From the impact of antibiotics on children to the hidden dangers of over-medication, we unpack the urgent need for more transparency and a shift towards addressing the root causes of illness.

In this episode, we discuss:

• The alarming increase in colon cancer among young people
• The microbiome's impact on overall health, from regulating the immune system to influencing mood and metabolism
• The deep influence of pharmaceutical companies on medical research, education, and policy, often at the expense of patient care
• The long-term health consequences of early antibiotic use in children
• The overmedication of Americans, particularly children, and the need for a shift towards addressing root causes of diseases

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This episode is brought to you by Seed, PerfectAmino, Timeline Nutrition, and LMNT.

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Heart disease, cancer, and stroke are the leading causes of death—and premature death at that—in the US. These diseases all have several risk factors in common, like smoking, physical inactivity, and poor diet, which policy often views simply as personal choices. We need to begin looking at disease prevention beyond individual decision-making.

In this podcast, I talk with Dr. Anand Parekh, Senator Bill Frist, and Dr. Dariush Mozaffarian on the need for government policymakers to address disease prevention.

Dr. Anand Parekh is the Bipartisan Policy Center’s chief medical advisor, providing clinical and public health expertise across the organization, particularly in the areas of aging, prevention, and global health. As a US Department of Health and Human Services deputy assistant secretary for health from 2008 to 2015, he developed and implemented national initiatives focused on prevention, wellness, and care management. He is the author of Prevention First: Policymaking for a Healthier America.

Senator Bill Frist is a heart and lung transplant surgeon and former US Senate majority leader. He led passage of the 2003 Medicare Modernization Act and the historic PEPFAR HIV/AIDS legislation that has saved millions of lives worldwide. As the founder and director of the Vanderbilt Multi-Organ Transplant Center, he has performed over 150 heart and lung transplants, authored over 100 peer-reviewed medical articles, and published seven books.

Dr. Dariush Mozaffarian is a cardiologist, Dean and Jean Mayer Professor at the Tufts Friedman School of Nutrition Science and Policy, and professor of medicine at Tufts Medical School. He has authored more than 400 scientific publications on dietary priorities for obesity, diabetes, and cardiovascular diseases and on evidence-based policy approaches to reduce these burdens in the US and globally. He has served in numerous advisory roles, including for the US and Canadian governments.⁣⁣ ⁣

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You’ve probably heard a lot about Robert F. Kennedy Jr., but beyond social media sound bites, do you really know where he stands on the issues shaping America’s health? Recorded last year when Kennedy was a presidential candidate, this episode of The Dr. Hyman Show provides a deep dive into his vision for improving the well-being of Americans. A vision Kennedy could put into action if confirmed as Secretary of Health and Human Services.

Kennedy is the founder of the Waterkeeper Alliance, the world’s largest clean water advocacy group, and served as its longtime chairman and attorney. He also founded the Children’s Health Defense and led efforts to address chronic disease and toxic exposures. As a litigator, he was part of the team that successfully prosecuted Monsanto for glyphosate’s link to cancer.

Tune in to explore Kennedy’s stance on tackling chronic disease, promoting regenerative farming, and improving the quality of the water we drink and the air we breathe.

In this episode, we discuss (audio version / Apple Subscriber version):

• The state of health in America (5:41 / 4:01)
• One of the main reasons RFK Jr. decided to run for president (8:39 / 6:59)
• The beginning of the autism epidemic (12:38 / 10:58)
• Addressing harms caused by ultra-processed food (15:03 / 13:23)
• Eliminating corporate culture in government agencies (33:05 / 28:41)
• America’s disproportionate deaths from COVID-19 (42:10 / 37:46)
• How America’s health status is affecting our national security (44:34 / 40:10)
• Solving the mental health crisis (47:41 / 43:17)
• Food and drug TV marketing (56:14 / 51:49)
• RFK’s thinking about fitness for himself and America (1:03:39 / 59:14)

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Food has become a more complex part of our lives than ever before. Much of what we think is food is actually many ingredients disguised as food, with entirely different, often negative impacts on the human body. Sadly, this is a greater problem here in the US than in other parts of the world, thanks to the food industry, corrupt intentions, and broken policies. Today, I talk about all this and more with my guest Jason Karp, whose personal experience of nearly going blind due to a toxic lifestyle led him to discover a different way; he made it his mission to get “back to human.”

In this episode, we discuss:

• Jason’s personal health journey and why that has prompted him to take on the campaign against Kellogg’s (7:53)
• The unhealthy state of America’s food industry (22:42)
• How Kellogg’s has one cereal formulation for Canada and another for the US that is full of chemicals (26:07)
• The correlation between food dyes and ADHD, and the failure of Kellogg's pledge (29:04)
• The political aspect of food regulation and dangers of unregulated food additives (32:55)
• Why we are in a state of metacrisis and what that means for our future (37:18)
• The bidirectional relationship between food and mental health (46:04)
• The financial burden of healthcare on the US government due to unhealthy diets (53:52)
• Supporting the Kellogg's Initiative: Sign the Petition (1:06:03)

We have a lot to do to shift our food system and eliminate harmful ingredients in the US, but there are ways to enact positive change starting today. We can all support a cleaner food industry and better health by voting with our dollar, purchasing real food, and getting involved in policy policy changes. I hope you’ll listen to this episode to learn more.

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What if the future of medicine isn’t about managing disease but erasing it? In this episode, I sit down with Dr. Darshan Shah to explore cutting-edge therapies like plasmapheresis and their potential to transform health and longevity. Together, we discuss how this innovative treatment reduces inflammation, supports recovery from long COVID, and improves aging biomarkers. Discover how personalized care and functional medicine could redefine how we approach healthspan and lifespan.

In this episode, we discuss:

• An overview of plasmapheresis, an advanced medical procedure that replaces plasma to reduce inflammation and aid recovery from chronic conditions.
• The potential of therapies like plasmapheresis to alleviate conditions such as Alzheimer's, autoimmune diseases, and long COVID.
• Leveraging natural stressors like heat, cold, and oxygen therapy to enhance mitochondrial function and extend lifespan.
• Exploring the critical role of reducing inflammation to improve overall health and prevent age-related diseases.
• The importance of diet, stress management, and environmental stressors in maintaining health and preventing disease.

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Do you experience cravings for sugar and refined carbs? Do you regularly feel tired or sluggish or experience brain fog? Do you have joint pain, muscle aches, bloating, gas, sinus problems, skin problems, anxiety, depression or insomnia, or simply put, do you “feel like crap?” Most people, at some point in their lives, have experienced what I call FLC Syndrome—this is when you Feel Like Crap. Yet most people have no idea what causes it or how to fix it. The good news is that most of us are only a few days away from feeling well, ending sugar and carb cravings, and having control over our bodies. 

In today’s episode, I talk about how to activate your body’s extraordinary healing and reparative systems with my 10-Day Detox Diet. The 10-Day Detox addresses foundational gaps missing in our modern diet, supplements that support our natural detoxification systems, minerals and amino acids that promote relaxation and deep rest, and a dietary protocol that works by taking out the wrong foods and focusing on the right foods to transform your body in just a few days.

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Here are more details from our interview (audio version / Apple Subscriber version):

• Do you have FLC Syndrome? (2:41 / 1:07) 
• The first pillar of the 10-Day Detox: Food (6:02 / 4:26) 
• The second pillar of the 10-Day Detox: Daily Habits (9:44 / 8:12)  
• The third pillar of the 10-Day Detox: Supplemental Support (12:31 / 10:59)
• What to eat and what to avoid during your 10-Day Detox (15:29 / 12:49) 
• Transitioning off the 10-Day Detox (22:28 / 20:54) 

Mentioned in this episode

10-Day Detox PDF (includes the medical symptom questionnaire)

The 10-Day Detox book

The 10-Day Detox Cookbook

What to Eat/What to Avoid during your 10-Day Detox

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Did you know many chronic diseases—like type 2 diabetes, anxiety, and fatigue—can be reversed? In this episode of “The Dr. Hyman Show,” Dr. Rangan Chatterjee breaks down how lifestyle changes, mindset shifts, and trusting your body can transform your health. We explore the hidden role of diet, stress, sleep, and movement in reversing illness naturally, while exposing what Western medicine often overlooks. If you’re ready to reclaim your health, this episode is your starting point.

In this episode, we discuss:

• Reversing Type 2 diabetes
• The dangers of ultra-processed foods and how cutting them out for as little as 10 days can significantly improve energy, sleep, and overall health.
• How socioeconomic factors, corporate influence, and environmental toxins contribute to chronic disease​.
• The power of journaling, meditation, and routines to create a sense of control in an unpredictable world.
• Practical, no-cost tools—like mindfulness, whole-food eating, and lifestyle tweaks—that anyone can use to improve their health.

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Transform your habits and unlock lasting change with Dr. Rangan Chatterjee's revolutionary approach in his newest book, Make Change That Lasts. Discover simple, science-backed strategies to create a life of health, happiness, and purpose—one small shift at a time.

This episode is brought to you by Seed.

Seed is offering my community 25% off to try DS-01® for themselves. Visit Seed.com/Hyman and use code 25HYMAN for 25% off your first month of Seed's DS-01® Daily Synbiotic.

Food is more than just fuel – every bite we take has a profound impact on our biology. In this episode, I explain the principles of the Pegan diet, emphasizing the importance of quality, nutrient-dense foods. Joining me are some incredible guests: Dr. Cindy Geyer, a renowned expert in functional medicine, and Dr. Elissa Epel, a leading stress researcher. Together, we’ll explore how chronic stress and poor sleep are intricately connected to major health issues like obesity, diabetes, and neurodegenerative diseases. Learn how specific dietary choices can serve as powerful medicine, improving your overall health and longevity. Plus, explore actionable tips and expert insights on integrating these health-boosting foods into your daily routine.

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Full-length episodes of these interviews can be found here:

How to Follow the Pegan Diet

What Is Driving Your Poor Sleep and How Can You Fix It?

How To Reduce The Harmful Effects of Chronic Stress

This episode is brought to you by Seed, ButcherBox, Vivobarefoot.

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We’ve all been there: one too many drinks and the next morning feels like a nightmare. But why does alcohol make us feel so terrible? In this episode of “The Doctor’s Farmacy,” I’m uncovering the surprising reasons behind hangovers and how you can avoid them. Get ready for expert tips on hydration, supplements, and the real truth about that ‘hair of the dog’ myth.

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Like most things in life, when it comes to optimizing metabolic health, a nuanced perspective can help. Rather than viewing it as a black-and-white issue, we can take into consideration the big-picture social context we’re facing that encourages ultra-processed foods, obesity, and lifelong medication as well as the micro-level of what people are experiencing as individuals and understanding how to help them when all else fails. 

Today I’m thrilled to sit down with Dr. Tyna Moore and Calley Means for a grounded discussion that explores both sides of the spectrum, and everything in between. 

In this episode, we discuss:

• The controversial discussion of GLP-1 agonists like Ozempic, weighing the pros and cons of these new drugs in treating obesity and metabolic crises (3:34)
• Challenging the notion of treating obesity with drugs like Ozempic (10:35)
• An unsettling revelation about the push for using Ozempic in children (12:04)
• Digging deeper into GLP-1 research and some of the benefits (32:51)
• Why are children being born metabolically challenged? (41:11)
• Dr. Moore’s approach to using peptides with her patients and for her own crippling pain, and what they’ve seen (45:19)
• How our current healthcare system lacks policies and support for behavior change (1:27)

While there are always differing views, we know for sure that our food and drug policies aren’t serving the best interests of creating sustainable, empowered health for the masses. I hope you’ll tune in to hear more from this comprehensive and lively discussion.

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A declining mind is one of the scariest things we can imagine. Yet, many of us walk around every day with brain fog, which is a clue that our brains (and our bodies) need some support. Left unchecked, there can be long-term consequences, and not just for your brain. The good news is that changes to diet, reducing toxic burden and stress, improving sleep and gut health, and getting good movement can work wonders to clear up any fogginess.

In this episode, Dr. Hyman speaks with Dr. Todd LePine and Max Lugavere about the Functional Medicine approach to reducing brain fog.

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Dr. Todd LePine

Dr. Mark Hyman

Max Lugavere

This episode is brought to you by Big Bold Health, Mitopure, and AG1.

Big Bold Health is offering my listeners 30% off their first order of HTB Rejuvenate Superfood. Head to Bigboldhealth.com and use code DrHyman30.

Support essential mitochondrial health and save 10% on Mitopure. Visit TimelineNutrition.com/Drhyman and use code DRHYMAN10.

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Tired of dealing with constant bloating and discomfort? In this episode, I break down the root causes of IBS and other common gut problems, from food sensitivities and SIBO to the gut-brain connection and stress. We’ll explore why ultra-processed foods are wreaking havoc on your gut, and I’ll walk you through the 5 R program and strategies like the low FODMAP diet to heal your gut for good. If you're suffering from bloating, constipation, or gas, this episode is your guide to real relief.

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This episode is brought to you by AG1, Essentia, and Big Bold Health.

AG1 is offering new subscribers a FREE $76 gift when you sign up. You’ll get a Welcome Kit, a bottle of D3K2, AND 5 free travel packs in your first box. Just go to DrinkAG1.com/hyman

Get an EXTRA $100 off your mattress purchase, on top of Essentia’s Holiday Sale. Use code HYMAN at checkout to get your extra savings. Learn more at myessentia.com/drmarkhyman.

Big Bold Health is offering my listeners 30% off their first order of HTB Rejuvenate Superfood when you go to Bigboldhealth.com/Mark.

What if you had a tool that helped you not only make better health decisions in the grocery store and restaurants but also gave you real-time feedback on how your body uniquely reacts to any kind of food? That is the beauty of wearable technology, and thanks to continuous glucose monitors this is something we’ll all be able to take advantage of in the near future. Levels is one company that’s been spearheading this field, providing an incredible amount of information on blood sugar responses and metabolic individuality. Today on “The Dr. Hyman Show,” I talk to Dr. Casey Means about what we can learn from the 51 million data points Levels has already gathered on blood glucose reactions, and so much more. 

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This episode is brought to you by Rupa Health, Pendulum, Thrive Market, and Pique.

Streamline your lab orders with Rupa Health. Access more than 3,500 specialty lab tests and register for a FREE live demo at RupaHealth.com.

Pendulum is offering listeners 20% off their first membership order at pendulumlife.com/farmacy Discount applied at checkout.

Head over to ThriveMarket.com/Hyman today to receive 30% off your first order and a free gift up to $60.

Head over to PiqueLife.com/Hyman20 and get up to 20% off + a complimentary beaker and rechargeable frother.

Metabolic health is key to preventing chronic diseases, which means it’s crucial for us to understand how our dietary choices impact our overall well-being. Simple changes in our eating habits can improve our insulin response and balance blood sugar levels, which offers immediate health benefits. In this episode, Jessie Inchauspe, Dr. Casey Means, and Dr. Ben Bikman share their actionable insights on boosting your metabolism through food. We delve into the latest research and provide practical tips for incorporating metabolism-friendly nutrition into your daily routine.

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Full-length episodes of these interviews can be found here:

Surprise Hacks To Balance Your Blood Sugar

The Secret to Longevity, Reversing Disease, and Optimizing Health: Fixing Metabolism

Reversing Chronic Disease And Aging By Fixing Insulin Resistance

This episode is brought to you by Seed, Cozy Earth, and Vivobarefoot.

Seed is offering my community 25% off to try DS-01® for themselves. Visit seed.com/hyman and use code 25HYMAN for 25% off your first month of Seed's DS-01® Daily Synbiotic.

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Have you ever wondered why you constantly feel tired, achy, or bloated? In this episode of “The Dr. Hyman Show,” I delve into "Feel Like Crap Syndrome," a term I coined to describe the chronic low-level systemic inflammation that affects so many of us. I’ll share my clinical insights on how ultra-processed foods and other dietary choices may explain why you’re feeling so run down. Plus, find out how a 10-day elimination diet can help you reset your health and live your best life.

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This episode is brought to you by AG1, Our Place, and Vivobarefoot.

AG1 is offering new subscribers a FREE $76 gift when you sign up. You’ll get a Welcome Kit, a bottle of D3K2, AND 5 free travel packs in your first box. Just go to DrinkAG1.com/hyman

Go to fromourplace.com and enter my code HYMAN at checkout to receive 10% off site-wide. Our Place offers a 100-day trial with free shipping and returns.

If you're not barefoot, go Vivobarefoot. Head to vivobarefoot.com/drhyman to get 20% off today!

Humans have coevolved with food and its medicinal actions on our bodies, meaning we have actual cell receptors for specific food-derived molecules. So why aren’t doctors trained in how to use food as medicine? We’re taught all about using pharmaceuticals to affect our biology, but the power of food is left high and dry. I think this is a foundational area of medical training we need to change. That’s why I’m so excited to talk to one of my favorite people and thinkers in the world of food and medicine on this episode of The Dr. Hyman Show, Dr. William Li. 

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This episode is brought to you by Rupa Health, ButcherBox, Beekeepers Naturals, and ARMRA.

Streamline your lab orders with Rupa Health. Access more than 3,500 specialty lab tests and register for a FREE live demo at RupaHealth.com.

ButcherBox is giving new members two pounds of ground beef for FREE in every box. Visit ButcherBox.com/Farmacy and use code FARMACY.

Head to BeekeepersNaturals.com/HYMAN and use the code ‘HYMAN’ to get 20% off sitewide.

Save 15% on your first order of ARMRA Colostrum and unlock the power of 400+ functional nutrients. Just visit TryARMRA.com/Mark or use code MARK.

Struggling with PMS or PCOS? It’s time to get to the root of the problem. In this episode of “The Dr. Hyman Show,” I revisit powerful conversations with Dr. Elizabeth Boham and Dr. Heather Huddleston to uncover the hidden triggers of hormonal imbalance. From the risks of hormonal birth control to the critical role of diet, we explore how stress, toxins, and inflammation wreak havoc on your hormones—and what you can do to fix it. Tune in for a personalized approach to achieving hormonal balance and reclaiming your health.

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Full-length episodes of these interviews can be found here:

The Hidden Cause of Your PMS and How to Fix It Fast

The Underlying Causes and Solutions for Women’s Hormonal Balances with Dr. Elizabeth Boham

The Root Causes And Treatment For PCOS

This episode is brought to you by Rupa Health, Mitopure, and AG1.

Streamline your lab orders with Rupa Health. Access more than 3,500 specialty lab tests and register for a FREE live demo at RupaHealth.com.

Support essential mitochondrial health and save 10% on Mitopure. Visit TimelineNutrition.com/Drhyman and use code DRHYMAN10.

AG1 is offering new subscribers a FREE $76 gift when you sign up. You’ll get a Welcome Kit, a bottle of D3K2, AND 5 free travel packs in your first box. Just go to DrinkAG1.com/hyman

Is your hair thinning, and you’re not sure why? It’s likely your body is trying to send you a message. In this episode of “The Dr. Hyman Show,” I reveal how hormones, stress, diet, and nutrient deficiencies all contribute to hair loss and thinning. You'll learn how insulin resistance, poor diet, and nutrient deficiencies accelerate hair loss—and the simple steps you can take right now to reverse it. 

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This episode is brought to you by Cozy Earth, Big Bold Health, and AX3.

Right now, you can save 40% when you upgrade to Cozy Earth sheets. Just head over to CozyEarth.com.

Big Bold Health is offering my listeners 30% off their first order of HTB Rejuvenate Superfood. Head to Bigboldhealth.com and use code DrHyman30.

Get 20% off your first order of AX3's astaxanthin at ax3.life/hyman with code HYMAN at checkout.

What if aging wasn’t inevitable, but something you could slow—or even reverse? In this episode of “The Dr. Hyman Show,” Dr. Eric Verdin, the president of the Buck Institute for Research on Aging, and I dive deep into the science of longevity. Discover how lifestyle choices, mitochondrial health, and cutting-edge research are transforming our understanding of aging. From fasting and nutrient sensing to emerging therapies like CD38 inhibitors, this episode reveals actionable insights to help you live a longer, healthier life.

In this episode, we discuss:

• The Role of Mitochondria in Aging
• The Critical Role of NAD Levels and Aging
• Lifestyle Interventions for Longevity
• Gene Therapy
• The Importance of CD38 and Enzyme Inhibition

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This episode is brought to you by Rupa Health, BIOptimizers, LMNT, and Fatty 15.

Streamline your lab orders with Rupa Health. Access more than 3,500 specialty lab tests and register for a FREE live demo at RupaHealth.com.

Don’t let stress take over your holidays. Try Magnesium Breakthrough from BiOptimizers. Head to Bioptimizers.com/Hyman and use code HYMAN10 to save 10%.

LMNT is giving listeners a FREE eight-count sample pack of their vital electrolyte drink mix with any purchase. Just visit DrinkLMNT.com/Hyman today.

Fatty15 contains pure, award-winning C15:0 in a bioavailable form. Get an exclusive 15% off a 90-day starter kit subscription. Just visit Fatty15.com and use code DRHYMAN10 to get started.

Can suffering be a path to growth? In this episode of “The Dr. Hyman Show,” Dr. Mark Hyman looks back on his conversations with Yung Pueblo, Tara Brach, and Dr. Robert Thurman to unpack how radical honesty, mindfulness practices, and embracing impermanence can ease our emotional pain. If you’ve ever struggled to let go of the past or find peace in the present, this episode offers actionable insights to transform your relationship with pain and personal growth.

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Full-length episodes of these interviews can be found here:

How To Let Go Of Suffering And Embrace What Is

How To Practice Radical Acceptance In All Areas Of Life

Why We Suffer And How Not To

Which diet really gives you the best shot at optimal health? On Wednesday December 4th, Mark Hyman, MD will answer that question during The Diet Wars, a LIVE digital experience. Joined by Dr. Gabrielle Lyon, they’ll break down the science, debunk the myths, and share their expert perspectives to help you make the best choices for your health. Find out more and get tickets now at https://www.moment.co/markhyman 

This episode is brought to you by OneSkin, AG1, and Seed.

Unlock your healthiest skin yet. Try OneSkin with 15% off your first purchase using code HYMAN15 at OneSkin.co today.

AG1 is offering new subscribers a FREE $76 gift when you sign up. You’ll get a Welcome Kit, a bottle of D3K2, AND 5 free travel packs in your first box. Just go to DrinkAG1.com/hyman

Seed is offering my community 25% off to try DS-01® for themselves. Visit seed.com/hyman and use code 25HYMAN for 25% off your first month of Seed's DS-01® Daily Synbiotic.

Acid reflux isn’t just uncomfortable—it could be the sign of deeper issues with your gut and overall health. In this episode of “The Dr. Hyman Show,” I reveal the hidden risks of long-term proton pump inhibitor (PPI) use—like nutritional deficiencies, gut issues, and even cognitive decline. More importantly, I share how you can manage reflux naturally with targeted lifestyle changes, soothing herbal remedies, and functional medicine strategies. Learn how to take control of your digestion and finally find lasting relief.

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Which diet really gives you the best shot at optimal health? On Wednesday December 4th, Mark Hyman, MD will answer that question during The Diet Wars, a LIVE digital experience. Joined by Dr. Gabrielle Lyon, they’ll break down the science, debunk the myths, and share their expert perspectives to help you make the best choices for your health. Find out more and get tickets now at https://www.moment.co/markhyman 

This episode is brought to you by Rupa University, Vivobarefoot, and AG1.

Rupa University is hosting FREE classes and bootcamps for healthcare providers who want to learn more about Functional Medicine testing. Sign up at RupaUniversity.com.

If you're not barefoot, go Vivobarefoot. Head to Vivobarefoot.com/DrHyman to get 20% off today!

Get your daily serving of vitamins, minerals, adaptogens, and more with AG1. Head to DrinkAG1.com/Hyman and get a year's worth of D3 and 10 Travel Packs for FREE with your first order.

When Jace Yawnick was diagnosed with cancer at 25, he could’ve given up. Instead, he built a platform that’s helping thousands of cancer patients. In this inspiring episode of “The Dr. Hyman Show,” Jace opens up to me about his fight and why early detection matters. We also explore the role of metabolic health, personalized care, and the crucial connection between nutrition and cancer treatment.

In this episode, we discuss:

• Jace’s unexpected diagnosis at age 25 with non-Hodgkin’s lymphoma, the symptoms he experienced, and the emotional challenges of facing a life-threatening illness at such a young age
• The crucial role that family, friends, social media, and even strangers played in supporting Jace emotionally, mentally, and practically during his treatment.
• Jace’s focus on eating clean, organic, nutrient-dense foods during treatment, and the mixed messages from his doctors regarding nutrition’s role in cancer recovery.
• Advancements like liquid biopsies and their potential to detect cancer early, empowering people to take a proactive approach to health.
• Jace’s decision to establish a nonprofit to support other cancer patients, focusing on financial aid and fostering connections between survivors and those currently battling cancer.

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Which diet really gives you the best shot at optimal health? On Wednesday December 4th, Mark Hyman, MD will answer that question during The Diet Wars, a LIVE digital experience. Joined by Dr. Gabrielle Lyon, they’ll break down the science, debunk the myths, and share their expert perspectives to help you make the best choices for your health. Find out more and get tickets now at https://www.moment.co/markhyman 

This episode is brought to you by Rupa Health, BIOptimizers, ARMRA, and Our Place.

Streamline your lab orders with Rupa Health. Access more than 3,500 specialty lab tests and register for a FREE live demo at RupaHealth.com.

Until November 28th, BIOptimizers is offering 25% off sitewide. Go to Bioptimizers.com/Hyman and use code Hyman10.

Save 15% on your first order of ARMRA Colostrum and unlock the power of 400+ functional nutrients. Just visit TryARMRA.com/Mark or use code MARK.

Upgrade your cookware, appliances and more with Our Place. Head over to FromOurPlace.com and enter code HYMAN at checkout to receive 10% off site-wide.

Chronic stress isn’t just an inconvenience—it’s a silent killer affecting your health in ways you might not realize. In this episode of “The Doctor’s Farmacy,” I revisit conversations with Dr. Rangan Chatterjee and Dr. Elissa Epel to uncover the truth about stress, its surprising connections to diet, and actionable strategies to combat its effects. Whether it’s balancing your blood sugar, improving your heart rate variability, or creating restorative daily habits, these insights will empower you to take control of your health.

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Full-length episodes of these interviews can be found here:

Is There An Antidote To Stress?

How Chronic Stress Creates Hormonal Havoc

How To Reduce The Harmful Effects Of Chronic Stress

Which diet really gives you the best shot at optimal health? On Wednesday December 4th, Mark Hyman, MD will answer that question during The Diet Wars, a LIVE digital experience. Joined by Dr. Gabrielle Lyon, they’ll break down the science, debunk the myths, and share their expert perspectives to help you make the best choices for your health. Find out more and get tickets now at https://www.moment.co/markhyman 

This episode is brought to you by Seed, ButcherBox, and Essentia.

Seed is offering my community 25% off to try DS-01® for themselves. Visit Seed.com/Hyman and use code 25HYMAN for 25% off your first month of Seed's DS-01® Daily Synbiotic.

ButcherBox is new users can select between ribeye, NY strip or filet mignon in every box for a year + 20 off. Visit ButcherBox.com/Farmacy and use code FARMACY.

Get an EXTRA $100 off your mattress purchase, on top of Essentia’s Big Black Friday Sale! Just use code HYMAN at checkout to get 25% OFF + an EXTRA $100 OFF + 2 FREE organic pillows ($330 value). Go to Myessentia.com/DrMarkHyman

Feeling that seasonal sniffle coming on? In this episode of “The Doctor’s Farmacy,” I share simple but powerful immunity hacks to help you fight off colds and keep your immunity defenses strong. Discover the science behind polyphenols—natural compounds in foods like green tea, dark chocolate, and citrus—and how they boost immunity by supporting gut health and reducing inflammation. Plus, learn why nutrients like vitamin C and zinc are essential allies in your fight against illness.

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Which diet really gives you the best shot at optimal health? On Wednesday December 4th, Mark Hyman, MD will answer that question during The Diet Wars, a LIVE digital experience. Joined by Dr. Gabrielle Lyon, they’ll break down the science, debunk the myths, and share their expert perspectives to help you make the best choices for your health. Find out more and get tickets now at https://www.moment.co/markhyman 

This episode is brought to you by Mitopure, Big Bold Health, AX3, and OneSkin.

Support essential mitochondrial health and save 10% on Mitopure. Visit TimelineNutrition.com/Drhyman and use code DRHYMAN10.

Big Bold Health is offering my listeners 30% off their first order of HTB Rejuvenate Superfood Head to Bigboldhealth.com and use code DrHyman30.

Get 20% off your first order of AX3's astaxanthin at ax3.life/hyman with code HYMAN at checkout.

Unlock your healthiest skin yet. Try OneSkin with 15% off your first purchase using code HYMAN15 at OneSkin.co today.

Is your thyroid the hidden culprit behind your fatigue, weight gain, or mood swings? In this episode, I uncover the vital role your thyroid health plays in energy, metabolism, and mood—and why its symptoms are often overlooked. Learn about comprehensive thyroid testing, the impact of toxins and stress, and practical diet and lifestyle tips to keep your thyroid in top shape.

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Full-length episodes of these interviews can be found here:

How To Treat The Root Cause Of Thyroid Problems

Is An Underactive Thyroid To Blame For Your Mysterious Symptoms? with Dr. Elizabeth Boham

A Root Cause Approach to Hyperthyroidism and Graves’ Disease

Which diet really gives you the best shot at optimal health? On Wednesday December 4th, Mark Hyman, MD will answer that question during The Diet Wars, a LIVE digital experience. Joined by Dr. Gabrielle Lyon, they’ll break down the science, debunk the myths, and share their expert perspectives to help you make the best choices for your health. Find out more and get tickets now at https://www.moment.co/markhyman 

This episode is brought to you by Seed, Cozy Earth, and AG1.

Seed is offering my community 25% off to try DS-01® for themselves. Visit Seed.com/Hyman and use code 25HYMAN for 25% off your first month of Seed's DS-01® Daily Synbiotic.

Right now, you can save 40% when you upgrade to Cozy Earth sheets. Just head over to CozyEarth.com.

Get your daily serving of vitamins, minerals, adaptogens, and more with AG1. Head to DrinkAG1.com/Hyman and get a year's worth of D3 and 10 Travel Packs for FREE with your first order.

Menopause doesn’t have to be a mystery. In this episode, I break down how you can navigate this transformative time and come out thriving. We'll explore the significant hormonal changes that occur, how they impact everything from bone density to mood, and what proactive steps you can take right now. I share insights on managing symptoms like hot flashes and sleep disruptions, the role of bioidentical hormone replacement therapy, and how healthy lifestyle choices like diet and exercise can make a world of difference.

View Show Notes From This Episode

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Which diet really gives you the best shot at optimal health? On Wednesday December 4th, Mark Hyman, MD will answer that question during The Diet Wars, a LIVE digital experience. Joined by Dr. Gabrielle Lyon, they’ll break down the science, debunk the myths, and share their expert perspectives to help you make the best choices for your health. Find out more and get tickets now at https://www.moment.co/markhyman 

This episode is brought to you by AG1, Vivobarefoot, and Big Bold Health.

Get your daily serving of vitamins, minerals, adaptogens, and more with AG1. Head to DrinkAG1.com/Hyman and get a year's worth of D3 and 10 Travel Packs for FREE with your first order.

If you're not barefoot, go Vivobarefoot. Head to Vivobarefoot.com/Drhyman to get 20% off today!

Big Bold Health is offering my listeners 30% off their first order of HTB Rejuvenate Superfood Head to Bigboldhealth.com and use code DrHyman30.

What if the path to happiness isn’t positivity, but honest reflection? Mark Manson, the bestselling author of “The Subtle Art of Not Giving a F*ck,” joins me to talk about why accepting life’s imperfections is the secret to true growth. Mark recounts his journey through fame, burnout, and a health crisis that forced him to confront the unhealthy beliefs he’d accepted about himself. 

In this episode, we discuss:

• The Impact of Success on Mental Health
• Self-Help Myths
• Growth Through Embracing Discomfort
• The Role of Scarcity in Creating Meaning
• The Role of Feedback in Self-Improvement
• Redefining Happiness and Success

Tune in for a refreshingly real look at self-improvement, mental health, and the power of embracing the uncomfortable truths.

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Which diet really gives you the best shot at optimal health? On Wednesday December 4th, Mark Hyman, MD will answer that question during The Diet Wars, a LIVE digital experience. Joined by Dr. Gabrielle Lyon, they’ll break down the science, debunk the myths, and share their expert perspectives to help you make the best choices for your health. Find out more and get tickets now at https://www.moment.co/markhyman

This episode is brought to you by Rupa Health, ButcherBox, BIOptimizers, and Beekeeper’s Naturals.

Streamline your lab orders with Rupa Health. Access more than 3,500 specialty lab tests and register for a FREE live demo at RupaHealth.com.

ButcherBox is giving new members two pounds of ground beef for FREE in every box. Visit ButcherBox.com/Farmacy and use code FARMACY.

During November, BIOptimizers is offering $100 with of free gifts with purchase at Bioptimizers.com/Hyman with code Hyman10.

Head to BeekeepersNaturals.com/HYMAN and use the code ‘HYMAN’ to get 20% off sitewide.