The Dr. Hyman Show

Erectile dysfunction is more than just a bedroom issue—it’s often an early indicator of more serious health problems. In this episode of “The Doctor’s Farmacy,” I look back on conversations with Dr. George Papanicolaou and Dr. George Shapiro to explore the surprising connections between sexual health and overall wellness and why ED is often an early indicator of metabolic issues, insulin resistance, and heart health. I’ll cover conventional treatments, as well as emerging therapies, and share how lifestyle changes in diet, exercise, and sleep can boost testosterone and improve sexual performance.

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Full-length episodes of these interviews can be found here:

The Science of Erectile Dysfunction and Unexpected Ways to Treat It

How To Treat Erectile Dysfunction Without The Little Blue Pill

The State of Science for Sex, Aging, and Regenerative Medicine

This episode is brought to you by Pique, LMNT, and Eight Sleep.

Head over to PiqueLife.com/Hyman20 and get up to 20% off + a complimentary beaker and rechargeable frother.

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Save three-hundred dollars off the POD 4 Ultra and two-hundred dollars off the Pod 4. Head to EightSleep.com/Mark.

Fasting isn’t just about skipping meals—it's a powerful tool to improve your health when done right. In this episode of “The Doctor’s Farmacy,” I tackle the most common myths about fasting and dive into the science behind how it impacts your metabolism, hormones, and overall well-being. You’ll learn how to navigate different fasting methods, from intermittent fasting to time-restricted eating, and discover how they can help you burn fat, preserve muscle, and even boost longevity.

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This episode is brought to you Mitopure, Rupa University, Big Bold Health, and AG1.

Support essential mitochondrial health and save 10% on Mitopure. Visit TimelineNutrition.com/Drhyman and use code DRHYMAN10.

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Big Bold Health is offering my listeners 30% off their first order of HTB Rejuvenate Superfood Head to Bigboldhealth.com and use code DrHyman30.

Get your daily serving of vitamins, minerals, adaptogens, and more with AG1. Head to DrinkAG1.com/Hyman and get a year's worth of D3 and 10 Travel Packs for FREE with your first order.

Imagine a pharmacy that tailors medications specifically for your body. In this episode, Dr. Mark Hyman speaks with Shaun Noorian, founder of Empower Pharmacy, about the resurgence of compounding pharmacies and how they’re addressing critical health needs. Learn how compounded medications are offering solutions for chronic conditions, drug shortages, and even hormone and peptide therapies that help patients thrive.

In this episode, we discuss:

• The Importance of Compounding Pharmacies
• The Impact of Compounding on Chronic Illness
• Hormone Replacement Therapy and Personalized Medicine
• Compounded Testosterone Treatments
• The Controversy Behind Semaglutides Like Ozempic

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This episode is brought to you by Rupa Health, Qualia, BIOptimizers, and Fatty15.

Streamline your lab orders with Rupa Health. Access more than 3,500 specialty lab tests and register for a FREE live demo at RupaHealth.com.

Decrease your "zombie cells" with Qualia Senolytic. Visit QualiaLife.com/Hyman to get 50% off and use code HYMAN for an additional 15% off your order.

During November, BIOptimizers is offering $100 with of free gifts with purchase at Bioptimizers.com/Hyman with code Hyman10.

Fatty15 contains pure, award-winning C15:0 in a bioavailable form. Get an exclusive 15% off a 90-day starter kit subscription. Just visit Fatty15.com and use code DRHYMAN10 to get started.

Good sleep does more than recharge you—it can improve your mental clarity, mood, and long-term health. In this episode of “The Doctor’s Farmacy,” Dr. Mark Hyman looks back on his conversations with experts Andrew Huberman, Bryan Johnson, and Dr. Cindy Geyer to explore how light, food, and stress affect your sleep quality. You’ll get actionable tips to fix your sleep routine and learn why a restorative night’s rest is critical for protecting against cognitive decline and chronic disease.

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Full-length episodes of these interviews can be found here:

How to Rewire Your Brain For Sleep

The Science of Living Longer: Diet, Supplements, & Sleep

What Is Driving Your Poor Sleep And How Can You Fix It?

This episode is brought to you by OneSkin and AX3.

Unlock your healthiest skin yet. Try OneSkin with 15% off your first purchase using code HYMAN15 at OneSkin.co today.

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Forget counting sheep—let’s talk about the simple and scientifically-proven tweaks that’ll have you sleeping like a pro. In this episode, I’m revealing my personal routine that turned my restless nights into deep, uninterrupted sleep. Learn how to fix those sneaky issues like blood sugar dips, nighttime stress, and even mouth breathing. If you’re tired of being tired, this is the episode you don’t want to miss.

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This episode is brought to you by AG1, Big Bold Health, and Seed.

Get your daily serving of vitamins, minerals, adaptogens, and more with AG1. Head to DrinkAG1.com/Hyman and get a year's worth of D3 and 10 Travel Packs for FREE with your first order.

Big Bold Health is offering my listeners 30% off their first order of HTB Rejuvenate Superfood. Head to Bigboldhealth.com and use code DrHyman30.

Seed is offering my community 25% off to try DS-01® for themselves. Visit Seed.com/Hyman and use code 25HYMAN for 25% off your first month of Seed's DS-01® Daily Synbiotic.

Navigating menopause doesn’t have to be difficult, but too often, women are left without the proper tools to manage their symptoms. In this episode, Dr. Mary Claire Haver joins me to unpack the real reasons behind hormonal imbalances during perimenopause and menopause. We dive deep into bioidentical hormone therapy, lifestyle changes, and how environmental toxins might be affecting your hormones more than you realize.

In this episode, we discuss:

• The benefits of using bioidentical hormones to manage menopausal symptoms and improve quality of life.
• Addressing hormonal imbalances early, before full menopause, to prevent more severe symptoms like osteoporosis and cardiovascular issues.
• How progesterone, especially in oral or topical form, can be a "miracle" solution for sleep and mood regulation during menopause.
• Estrogen’s role in cardiovascular and sexual health
• The "menopause toolkit," which includes hormone therapy, nutrition, exercise, sleep optimization, and stress reduction
• The impact of environmental toxins, such as endocrine disruptors, on women’s hormonal health, particularly during menopause.

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This episode is brought to you by Rupa Health, Mitopure, LMNT, and Wonderfeel.

Streamline your lab orders with Rupa Health. Access more than 3,500 specialty lab tests and register for a FREE live demo at RupaHealth.com.

Support essential mitochondrial health and save 10% on Mitopure. Visit TimelineNutrition.com/Drhyman and use code DRHYMAN10.

LMNT is giving listeners a FREE eight-count sample pack of their vital electrolyte drink mix with any purchase. Just visit DrinkLMNT.com/Hyman today.

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Most of us take breathing for granted, but it holds the key to transforming your health. In this episode, I dive into powerful conversations with James Nestor and Wim Hof about how mastering your breath can boost your immune system, reduce stress, and even manage chronic inflammation. You’ll discover why nose breathing is essential for overall wellness, how cold exposure enhances cardiovascular health, and why The Wim Hof Method is changing lives. If you’ve been ignoring your breath, it’s time to wake up—this episode will show you how to harness the power of breath for better physical and mental health.

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Full-length episodes of these interviews can be found here:

The Power Of Breath As Medicine

Why Ice Water Immersion And Your Breath Is The Key To Health And Happiness

This episode is brought to you by AG1, ButcherBox, and Fatty15.

Get your daily serving of vitamins, minerals, adaptogens, and more with AG1. Head to DrinkAG1.com/Hyman and get a year's worth of D3 and 10 Travel Packs for FREE with your first order.

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Feeling tired, sick, or struggling with stubborn health issues? It might be time to check your vitamin D levels. In this episode, I explore why vitamin D is the secret to better health—covering everything from its role in preventing chronic diseases like heart disease and cancer to how it boosts your immune system. I’ll break down the symptoms of deficiency, why regular testing is a must, and how to get vitamin D safely through sun exposure and supplements.

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This episode is brought to you by AG1, Vivobarefoot, and Eight Sleep.

Get your daily serving of vitamins, minerals, adaptogens, and more with AG1. Head to DrinkAG1.com/Hyman and get a year's worth of D3 and 10 Travel Packs for FREE with your first order.

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Is the thought of aging holding you back, or could it be your chance to thrive? On this episode of “The Doctor’s Farmacy,” I sit down with Chip Conley to challenge the outdated view of midlife as a time of decline. We explore how this stage can become a period of growth, from finding new passions to building deeper connections. Learn why happiness often increases after 50 and get actionable tips for staying active, curious, and engaged.

In this episode, we discuss:

• Research on the U-curve of happiness, showing that life satisfaction typically dips around ages 45-50 but improves steadily with each decade after.
• The importance of social wellness and relationships as a key factor for longevity and well-being
• The Modern Elder Academy
• Overcoming the fear of aging
• The importance of maintaining curiosity and openness to new experiences, which are strongly correlated with living a longer, happier life.

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This episode is brought to you by Rupa University, BIOptimizers, Armra, and Qualia.

Rupa University is hosting FREE classes and bootcamps for healthcare providers who want to learn more about Functional Medicine testing. Sign up at RupaUniversity.com.

Tackle an overlooked root cause of stress with Magnesium Breakthrough. Visit Bioptimizers.com/hyman and use code HYMAN10 to save 10%.

Save 15% on your first order of ARMRA Colostrum and unlock the power of 400+ functional nutrients. Just visit TryARMRA.com/Mark or use code MARK.

Decrease your "zombie cells" with Qualia Senolytic. Visit QualiaLife.com/Hyman to get 50% off and use code HYMAN for an additional 15% off your order.

80% of us aren’t getting enough magnesium—and this impacts everything from migraines to muscle cramps, blood pressure, and even stress levels. On this episode of “The Doctor’s Farmacy,” I share insights from top experts like Dr. Todd LePine, Dr. George Papanicolaou, and Dr. Elizabeth Boham on how magnesium impacts your overall well-being. Learn why standard tests often miss a magnesium deficiency, how to get tested properly, and which foods and supplements can help you restore your levels. Don’t ignore this crucial mineral—your health depends on it.

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Full-length episodes of these interviews can be found here:

How Magnesium Deficiency Impacts Your Health | Know Your Numbers

The Functional Medicine Approach To Ending Migraines

Treating The Underlying Causes Of High Blood Pressure with Dr. George Papanicolaou

Supplements: Useful Or Useless? with Dr. Elizabeth Boham

This episode is brought to you by Rupa Health and Big Bold Health.

Streamline your lab orders with Rupa Health. Access more than 3,500 specialty lab tests and register for a FREE live demo at RupaHealth.com.

Big Bold Health is offering my listeners 30% off their first order of HTB Rejuvenate Superfood. Head to Bigboldhealth.com and use code DrHyman30.

We’ve all been there: one too many drinks and the next morning feels like a nightmare. But why does alcohol make us feel so terrible? In this episode of “The Doctor’s Farmacy,” I’m uncovering the surprising reasons behind hangovers and how you can avoid them. Get ready for expert tips on hydration, supplements, and the real truth about that ‘hair of the dog’ myth.

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This episode is brought to you by Mitopure, AG1, and Big Bold Health.

Support essential mitochondrial health and save 10% on Mitopure. Visit TimelineNutrition.com/Drhyman and use code DRHYMAN10.

Get your daily serving of vitamins, minerals, adaptogens, and more with AG1. Head to DrinkAG1.com/Hyman and get a year's worth of D3 and five Travel Packs for FREE with your first order.

Big Bold Health is offering my listeners 30% off their first order of HTB Rejuvenate Superfood. Head to Bigboldhealth.com and use code DrHyman30.

Stress isn’t just in your head—it’s rewiring your brain. In this episode, I sit down with Dr. Robert Sapolsky to dive into the science of stress and its profound impact on mental and physical health. We explore how chronic stress damages the brain, particularly the hippocampus, leading to cognitive decline and mood disorders. Tune in to learn powerful strategies for managing stress, from mindfulness to exercise, and discover what it means for your health and society at large.

In this episode, we discuss:

• The difference between short-term (acute) stress, which can be beneficial in small doses, and long-term (chronic) stress
• The impact of stress on brain health
• The argument that free will is an illusion, as our decisions and behaviors are largely driven by complex biological processes and environmental factors
• How stress interacts with genes and the environment, influencing behavior, health outcomes, and the body's ability to cope with stress
• How chronic stress triggers inflammation throughout the body, contributing to various health problems
• Effective ways to manage stress, including mindfulness, physical exercise, and proper nutrition

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This episode is brought to you by Rupa Health, Pendulum, Thrive Market, and Our Place.

Streamline your lab orders with Rupa Health. Access more than 3,500 specialty lab tests and register for a FREE live demo at RupaHealth.com.

Pendulum is offering listeners 20% off their first membership order at pendulumlife.com/farmacy. Discount applied at checkout.

Head over to ThriveMarket.com/Hyman today to received 30% off your first order and a free gift up to $60.

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What if you could train your brain to handle stress better—just by meditating for a few minutes each day? In this episode of “The Doctor’s Farmacy,” I revisit conversations with Emily Fletcher, Dan Harris, and Daniel Goleman to explore how meditation rewires the brain, reduces anxiety, and enhances mental clarity. You’ll learn the science behind mindfulness, loving-kindness meditation, and other techniques that not only improve stress management but also promote overall mental health and wellness.

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Full-length episodes of these interviews can be found here:

Why Meditation is the New Medicine

Is one minute of meditation enough?

Meditation, Kindness, and Compassion: The Secret to Your Life and Financial Abundance

This episode is brought to you by Pique, Seed, and Ketone-IQ.

Head over to PiqueLife.com/Hyman20 and get up to 20% off + a complimentary beaker and rechargeable frother.

Seed is offering my community 25% off to try DS-01® for themselves. Visit seed.com/hyman and use code 25HYMAN for 25% off your first month of Seed's DS-01® Daily Synbiotic.

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Are you up to date on the doctor appointments that could save your life? In this episode, I dive into the essential screenings you can’t afford to skip, from mammograms and colonoscopies to functional lab tests that reveal much more than standard checkups. We’ll break down how conventional medicine is great for emergency care and early detection, but it often misses the root causes of illness.

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This episode is brought to you by AG1 and Essentia.

Get your daily serving of vitamins, minerals, adaptogens, and more with AG1. Head to DrinkAG1.com/Hyman and get a year's worth of D3 and five Travel Packs for FREE with your first order.

Visit myessentia.com/drmarkhyman and use code HYMAN for $100 off your mattress purchase

Every tap, like, and scroll on social media is feeding a mental health epidemic—and it’s targeting our youth. In honor of World Mental Health Day, a day dedicated to raising awareness and mobilizing efforts to support mental health worldwide, I'm sitting down with renowned social psychologist and author Jonathan Haidt, PhD to explore the dramatic rise in anxiety and depression among today’s youth. We’ll dive into the evolution of internet culture, the role of food systems in social disruption, and how we can turn the tide on these trends. If you’re concerned about the mental well-being of the next generation, tune in for actionable solutions.

In this episode, we discuss:

• The Rise of Depression and Anxiety in Gen Z
• The Link Between Social Media and Mental Health
• The Addictive Nature of Social Media Algorithms
• The Evolution of the Internet and Its Role in Childhood
• The Phone-Free Schools Movement
• The Influence of Ultra-Processed Foods on Mental Health

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This episode is brought to you by Rupa University, ButcherBox, Sunlighten, and Fatty15.

Practitioners: Dr. Casey Means is hosting a free class on metabolic dysfunction. To sign up, go to rupahealth.com/casey.

ButcherBox is giving new members two pounds of wild-caught salmon for FREE plus $30 off. Visit ButcherBox.com/Farmacy and use code FARMACY30.

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Fatty15 contains pure, award-winning C15:0 in a bioavailable form. Get an exclusive 10% off a 90-day starter kit subscription. Just visit Fatty15.com and use code DRHYMAN10 to get started.

Did you know changing your diet can dramatically reduce ADD/ADHD symptoms? In this episode, I look back on my conversations with Dr. George Papanicolaou, Dr. Jaquel Patterson, and Dr. Uma Naidoo on how sugar, gluten, and toxins like heavy metals are disrupting brain function and fueling these chronic disorders. You’ll discover the power of nutrient-dense foods, gut health, and functional medicine in managing ADD and ADHD naturally. If you're looking for solutions beyond medication, this episode gives you the tools to start healing from the inside out.

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Full-length episodes of these interviews can be found here:

Why ADHD Is Not A Psychiatric Disorder Or Brain Disease with Dr. George Papaicolaou

What’s Fueling Our Mental Health Crisis and How Can We Fix it? With Dr. Jaquel Patterson

Is Food to Blame for Your Anxiety and Depression?

This episode is brought to you by AX3, Mitopure, Seed, and OneSkin.

Get 20% off your first order of AX3's astaxanthin at ax3.life/hyman with code HYMAN at checkout.

Support essential mitochondrial health and save 10% on Mitopure. Visit TimelineNutrition.com/Drhyman and use code DRHYMAN10.

Seed is offering my community 25% off to try DS-01® for themselves. Visit seed.com/hyman and use code HYMAN25 for 25% off your first month of Seed's DS-01® Daily Synbiotic.

Unlock your healthiest skin yet. Try OneSkin with 15% off your first purchase using code HYMAN15 at OneSkin.co today.

Cancer rates are on the rise, but what you eat can make all the difference. In this episode, I explore the powerful relationship between food and cancer risk. From cutting down on sugar and processed foods to boosting your intake of anti-cancer superfoods like cruciferous vegetables and mushrooms, I’ll walk you through why a whole-food, nutrient-dense diet is your best defense against this disease.

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This episode is brought to you by Rupa Health, Manukora Honey, and Eudemonia.

Streamline your lab orders with Rupa Health. Access more than 3,500 specialty lab tests and register for a FREE live demo at RupaHealth.com.

Get your Manukora Honey Starter Kit today! Just head to Manukora.com/Hyman, to get $25 off.

For the full lineup and to purchase a ticket, visit Eudemonia.net.

What if we could predict disease before it even starts? In this episode, I’m joined by Dr. Jeremy Nicholson to explore the cutting-edge science of precision medicine and how understanding your unique biology could hold the key to preventing illness. We dive into the future of diagnostics, the power of the exposome in shaping your health, and how advancements like gene editing could revolutionize treatment. 

In this episode, we discuss:

• The emerging field of phenomic medicine
• Moving away from one-size-fits-all treatments toward more personalized medical approaches based on individual biology
• Long COVID and its impact
• The critical role of the microbiome in overall health, immune system function, and its direct influence on diseases
• How the exposome, or all of the environmental exposures a person experiences, plays a crucial role in shaping health outcomes
• Advanced technologies like metabolic profiling, which can reveal subtle biochemical signals and identify disease risks long before symptoms appear.
• How gene-environment interactions drive the development of complex diseases, making personalized medical approaches crucial for effective treatment

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This episode is brought to you by Rupa Health, Cozy Earth, BIOptimizers, and Neurohacker.

Streamline your lab orders with Rupa Health. Access more than 3,500 specialty lab tests and register for a FREE live demo at RupaHealth.com.

Right now, you can save 40% when you upgrade to Cozy Earth sheets. Just head over to CozyEarth.com.

Tackle an overlooked root cause of stress with Magnesium Breakthrough. Visit Bioptimizers.com/hyman and use code HYMAN10 to save 10%.

Decrease your "zombie cells" with Qualia Senolytic. Visit QualiaLife.com/Hyman to get 50% off and use code HYMAN for an additional 15% off your order.

Have you ever wondered why it’s so hard to put down that bag of chips? In this episode, my guests Dr. Shebani Sethi and Calley Means and I break down how ultra-processed foods are contributing to the obesity epidemic, diabetes, heart disease, and even mental health issues. From understanding the science of addiction to decoding food labels, we’ll explore how big food companies are manipulating us—and what we can do to fight back.

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Full-length episodes of these interviews can be found here:

Why the Last Thing that Should Ever Eat is Ultra Processed Foods: It Kills 11 Million People a Year

How Does Ultra-Processed Food Affect Our Mental Health?

Calley Means: The Obesity Crisis, Ozempic, ADHD and Food Industry Lies

This episode is brought to you by Rupa Health, FOND, Ketone-IQ, and Happy Egg.

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Shopping for better eggs shouldn’t be confusing. Look for the yellow carton at your local grocery store or visit HappyEgg.com/Farmacy to find Happy Egg near you to get 50% off.

Most people have no idea they’re missing out on essential nutrients—until it’s too late. In this episode, I expose the hidden truth behind nutrient deficiencies and why supplements are no longer optional when it comes to your health. Learn which supplements are vital to keep you feeling your best and how to navigate the confusing supplement market with confidence.

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This episode is brought to you by AG1, Seed, and Essentia.

Get your daily serving of vitamins, minerals, adaptogens, and more with AG1. Head to DrinkAG1.com/Hyman and get a year's worth of D3 and five Travel Packs for FREE with your first order.

Seed is offering my community 25% off to try DS-01® for themselves. Visit seed.com/hyman and use code HYMAN25 for 25% off your first month of Seed's DS-01® Daily Synbiotic.

Get an EXTRA $100 off your mattress purchase, on top of Essentia’s Labor Day Sale of 25% OFF + FREE organic cotton sheets! Head to MyEssentia.com/DrMarkHyman and use code HYMAN at checkout.

Fatty liver disease is on the rise, but the good news is, it’s preventable and reversible. In this episode, I sit down with Dr. Yousef Elyaman to explore the silent epidemic and how early detection could be the key to saving your liver—and your health. We break down the latest in diagnostic tools and dive into powerful lifestyle interventions. Whether you’ve been diagnosed or want to stay ahead of the game, this episode is packed with practical advice to protect your liver and your health.

In this episode, we discuss:

• The importance of diagnosing fatty liver disease early through blood tests
• How dietary interventions, particularly the Mediterranean diet, can significantly improve or even reverse fatty liver disease
• Supplements that support liver function and reverse fatty liver disease
• How insulin resistance is a major contributor to fatty liver disease and why managing blood sugar levels is critical for liver health
• The connection between chronic inflammation and fatty liver disease
• How exposure to toxins and chemicals, including processed foods and environmental pollutants, contribute to liver damage and fatty liver disease

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This episode is brought to you by Rupa Health, BIOptimizers, LMNT, and Manukora Honey.

Streamline your lab orders with Rupa Health. Access more than 3,500 specialty lab tests and register for a FREE live demo at RupaHealth.com.

Tackle an overlooked root cause of stress with Magnesium Breakthrough. Visit Bioptimizers.com/Hyman and use code HYMAN10 to save 10%.

LMNT is giving listeners a FREE eight-count sample pack of their vital electrolyte drink mix with any purchase. Just visit DrinkLMNT.com/Hyman today.

Get your Manukora Honey Starter Kit today! Just head to Manukora.com/Hyman, to get $25 off.

Struggling with skin issues like acne or rosacea? In this episode, I team up with Dr. Todd LePine and Dr. Elizabeth Boham to dive deep into the root causes behind chronic skin conditions. We break down how gut health, food sensitivities, and systemic inflammation are often at the heart of these issues. Learn how eliminating processed foods, gluten, and dairy can transform your skin, and why treating from the inside out is the key to lasting skin health.

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Full-length episodes of these interviews can be found here:

Treating Adult Acne & Rosacea From The Inside Out

How To Heal Skin Issues By Optimizing Your Nutrient Status And Fixing Your Gut

Treating Acne From The Inside Out with Dr. Elizabeth Boham

This episode is brought to you by Eudemonia, ButcherBox, and Cozy Earth.

For the full lineup and to purchase a ticket, visit Eudemonia.net.

ButcherBox is giving new members two pounds of wild-caught salmon for FREE plus $30 off. Visit ButcherBox.com/Farmacy and use code FARMACY30.

Right now, you can save 40% when you upgrade to Cozy Earth sheets. Just head over to CozyEarth.com.

Think weight training is just for bodybuilders? In this episode, I break down why building muscle is one of the most important things you can do for your long-term health. From improving insulin resistance and boosting your metabolism to enhancing mental clarity and protecting against chronic diseases like diabetes, heart disease, and Alzheimer's—muscle is the secret weapon you didn’t know you needed. I’ll also share practical tips for incorporating strength training into your routine, no matter your age or fitness level.

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This episode is brought to you by Mitopure, OneSkin, Seed, and AX3.

Support essential mitochondrial health and save 10% on Mitopure. Visit TimelineNutrition.com/Drhyman and use code DRHYMAN10.

Unlock your healthiest skin yet. Try OneSkin with 15% off your first purchase using code HYMAN15 at OneSkin.co today.

Seed is offering my community 25% off to try DS-01® for themselves. Visit seed.com/hyman and use code HYMAN25 for 25% off your first month of Seed's DS-01® Daily Synbiotic.

Get 20% off your first order of AX3's astaxanthin at Ax3.Life/Hyman with code HYMAN at checkout.

Have you ever experienced unexplained allergy-like symptoms, digestive issues, or persistent fatigue? It could be histamine intolerance, a condition that’s more common than you think. In this episode, Dr. Elizabeth Boham joins me to examine real patient stories, dive deep into the gut-brain connection, and share how you can manage histamine intolerance through personalized treatments, stress management, and gut health optimization. Whether it's genetic or lifestyle-related, histamine intolerance doesn't have to be a lifelong battle. 

In this episode, we discuss:

• The common symptoms of histamine intolerance
• The importance of the DAO enzyme
• Why low-histamine diets may not be a long-term solution
• Why stress and gut health are key triggers
• The difference between histamine intolerance and and mast cell activation syndrome (MCAS)

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This episode is brought to you by Rupa Health, Pendulum, ARMRA, and Our Place.

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Is going gluten-free just a trend, or is it a legitimate step toward better health? In this episode, I’m joined by Dr. Alessio Fasano and Maggie Ward to explore the science behind gluten sensitivity and why modern bread could be at the root of many gut issues. We dive into the debate over gluten-free diets, discussing whether they’re necessary for everyone or only for those with celiac disease. We also examine how environmental factors like pesticides and hybridized wheat are disrupting the gut microbiome, leading to issues like leaky gut syndrome.

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Is Gluten-Free A Fad Or Is Gluten A Real Threat To Our Health?

Should We All Avoid Gluten?

What Would Happen If You Stopped Eating Bread For 30 Days?

This episode is brought to you by Momentous, AG1, and Happy Egg.

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Tired of dealing with constant bloating and discomfort? In this episode, I break down the root causes of IBS and other common gut problems, from food sensitivities and SIBO to the gut-brain connection and stress. We’ll explore why ultra-processed foods are wreaking havoc on your gut, and I’ll walk you through the 5 R program and strategies like the low FODMAP diet to heal your gut for good. If you're suffering from bloating, constipation, or gas, this episode is your guide to real relief.

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This episode is brought to you by AG1 and Rupa University.

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Muscle isn’t just about strength—it’s about longevity, metabolic health, and even immune function. In this episode, I sit down with Dr. Gabrielle Lyon to uncover the critical role that skeletal muscle plays in our overall health. We dive deep into muscle as an endocrine organ, its role in fighting insulin resistance, and why sedentary lifestyles are wreaking havoc on our bodies. From understanding how to build muscle effectively at any age to learning why muscle mass is the key to metabolic health, this conversation will change the way you think about strength training.

In this episode, we discuss:

• Exactly how much protein we need to eat every day
• The differences between plant and animal proteins
• The impact of resistance training
• The metabolic benefits of muscle
• Why you should spread your protein intake evenly throughout the day
• How sedentary behavior and insufficient protein intake can lead to muscle loss, insulin resistance, and metabolic disorders

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This episode is brought to you by Rupa Health, Beekeepers Naturals, Thrive Market, and Fatty15.

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Are you getting enough vitamin D? This powerful nutrient does so much more than just support bone health—it’s essential for mood, energy, immunity, and even protection against serious diseases like cancer and COVID. Yet, approximately 80% of Americans are deficient due to limited sun exposure and the depletion of nutrients in our modern food supply. In this episode, I break down why vitamin D is critical for your health, the optimal levels you should aim for, and how to get your daily dose safely—whether through the sun, diet, or supplements.

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Full-length episodes of these interviews can be found here:

Do You Need To Take Vitamin D?

Supplements: Useful Or Useless? with Dr. Elizabeth Boham

The Science Behind Vitamin D, Our Rampant Deficiency, And Its Harmful Impact On Our Health

This episode is brought to you by Pique, Eudemonia, Ketone-IQ, and Happy Egg.

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We often think of trauma as those big, life-shattering events, but did you know that everyday stress can have the same lasting impact on your health? In this episode, I break down how both major and minor traumas affect your body at the deepest level—from your gut to your brain—and what you can do to heal. We’ll dive into the science of how trauma shapes your biology and explore the functional medicine strategies that go beyond traditional talk therapy. Whether you’ve been through a major event or are feeling the weight of everyday stress, this episode offers powerful tools to help you not just survive, but thrive.

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What if the key to fixing our broken healthcare system lies within Congress? On this episode of “The Doctor’s Farmacy,” I sit down with U.S. Representative Vern Buchanan to tackle one of the biggest crises facing our country: the rise of chronic disease and its staggering economic impact. We dive deep into why prevention, not just treatment, needs to be at the forefront of healthcare, and discuss the groundbreaking work being done in Congress to shift our focus toward nutrition, lifestyle changes, and medically tailored meals. 

In this episode, we discuss:

• The staggering economic burden of chronic diseases on the U.S. economy
• The importance of nutrition education for doctors and healthcare providers as a key factor in preventing chronic diseases
• Congressman Vern Buchanan’s bipartisan efforts to address the chronic disease epidemic through policy changes and initiatives like the Congressional Preventive Health and Wellness Caucus
• The impact of chronic disease on military readiness and national security
• The critical need for a shift in healthcare focus from treatment to prevention, emphasizing lifestyle changes and nutrition

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Did you know chronic stress can age your immune system faster than almost anything else? In this episode, I dive into the fascinating world of immune and lymph health with some of the leading experts in the field, including Dr. Mehmet Oz, Dr. Gerald Lemole, and Dr. Leonard Calabrese. We explore how stress, diet, and lifestyle can either rejuvenate or break down your immune defenses, leading to a host of chronic conditions. Learn practical, science-backed strategies to boost your immune resilience, reduce inflammation, and keep your body’s defenses in top shape.

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Full-length episodes of these interviews can be found here:

How To Reset Your Immune System At A Cellular Level

Why Our Neglected Lymph System Is A Key To Optimal Health

The Secrets to Creating a Healthy Immune System

This episode is brought to you by Mitopure, Eudemonia, SleepMe, and Sunlighten.

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Could your persistent acne, eczema, or psoriasis be a sign of something more serious? Join me on "The Doctor’s Farmacy" as I reveal how chronic skin conditions are often linked to gut health and nutrient deficiencies. I’ll share practical tips on how to support your skin by healing your gut, optimizing your diet, and identifying the root causes of inflammation. It’s time to understand what your skin is really telling you and how to fix it.

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This episode is brought to you by AG1 and Essentia.

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Do you ever feel like the more meds you take, the worse you feel? The problem might lie in how our healthcare system operates. In this episode, I sit down with Dr. Marty Makary to tackle the alarming rise of colon cancer among young people, explore how our microbiome plays a crucial role in preventing chronic diseases, and discuss the unsettling influence of the pharmaceutical industry on medical practices. From the impact of antibiotics on children to the hidden dangers of over-medication, we unpack the urgent need for more transparency and a shift towards addressing the root causes of illness.

In this episode, we discuss:

• The alarming increase in colon cancer among young people
• The microbiome's impact on overall health, from regulating the immune system to influencing mood and metabolism
• The deep influence of pharmaceutical companies on medical research, education, and policy, often at the expense of patient care
• The long-term health consequences of early antibiotic use in children
• The overmedication of Americans, particularly children, and the need for a shift towards addressing root causes of diseases

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Did you know that sugar is lurking in more places than you might think, and it could be sabotaging your health in ways you never imagined? In this episode, I look back on my conversations with Dr. Richard Johnson and Dr. Robert Lustig. We examine how certain foods, especially those loaded with sugar, can trigger overeating, disrupt your metabolism, and lead to a cascade of health issues. Plus, I'll share practical strategies for detoxing from sugar, managing blood sugar levels, and reclaiming your health.

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Full-length episodes of these interviews can be found here:

Why Sugar And Fructose Are So Deadly with Dr. Richard Johnson

Depressed or Anxious? You May Never Eat Sugar Again After Watching This

The True Dangers Of Sugar with Dr. Robert Lustig

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Are you tired of feeling tired all the time? You're not alone—burnout is one of the most common complaints I hear from patients. In this episode, I dive into the root causes of chronic fatigue, including how mitochondrial dysfunction could be sabotaging your energy levels. I’ll share my personal journey with chronic fatigue and explain how functional medicine can help you boost your energy and finally feel like yourself again.

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In a world where chronic illness and unexplained health issues are on the rise, understanding the root causes behind immune dysfunction is more important than ever. In this episode of "The Doctor's Farmacy," I'm joined by Dr. Elroy Vojdani to explore the critical issue of immune resilience and its connection to chronic illness. Dr. Vojdani shares groundbreaking insights from his father’s work on immune health, along with practical strategies to boost your immune system, tackle long COVID, and reverse chronic conditions through personalized, functional medicine approaches.

In this episode, we discuss:

• The Decline of Immune Resilience
• The Role of the Gut in Immune Health
• The Impact of Long COVID on the Immune System
• Molecular Mimicry and Autoimmunity
• The Connection Between Mitochondrial Dysfunction and Chronic Illness

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This episode is brought to you by Rupa Health, Pendulum, Neurohacker, Our Place, and Manukora Honey.

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Ever wondered why you’re always tired, achy, or just not feeling your best? It could be chronic inflammation silently wreaking havoc on your health—but the good news is, there’s a way to stop it. Joined by experts Dr. Shilpa Ravella and Dr. David Furman, we explore the surprising ways your diet, environment, and even your daily habits might be fueling this silent killer. We break down the science behind inflammation, how it’s linked to almost every chronic disease, and what you can do to stop it in its tracks.

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What Causes Inflammation And How Can You Treat It?

The Silent Killer: Inflammation And Chronic Disease

How Silent Inflammation Accelerates Aging

This episode is brought to you by Momentous, ButcherBox, and SleepMe.

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What if I told you that your breakfast habits might be sabotaging your entire day? In this episode of “The Doctor’s Farmacy,” I’m diving into the science behind starting your day right. Discover why a high-protein, nutrient-dense breakfast can set the tone for balanced blood sugar, reduced cravings, and improved cognitive performance. Plus, I’ll offer up some practical tips for making breakfast a powerful tool for maintaining a healthy weight and preventing chronic diseases.

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Did you know that inflammation could be the hidden culprit behind the skyrocketing rates of mental illness? In this episode, I sit down with Dr. Jaquel Patterson to discuss one of today's most pressing issues: the alarming rise in mental health disorders like depression, anxiety, ADHD, and bipolar disorder. We explore the connection between mental health, inflammation, and immune function, shedding light on post-COVID mental health challenges, brain inflammation, and the impact of environmental factors.

In this episode, we discuss:

• The mental health impacts observed post-COVID, highlighting the exacerbation of pre-existing conditions and new onset issues.
• The connection between brain inflammation and mental health disorders, emphasizing the role of chronic inflammation in conditions like depression and schizophrenia.
• The impact of environmental toxins on mental health.
• The potential benefits of sauna therapy for reducing inflammation and improving mental health.
• Functional medicine strategies for treating mental health disorders, including dietary changes, nutrient supplementation, and lifestyle modifications.

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This episode is brought to you by Rupa Health, ARMRA, Thrive Market, and Fatty15.

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Save 15% on your first order of ARMRA Colostrum and unlock the power of 400+ functional nutrients. Just visit TryARMRA.com/Mark or use code MARK.

Head over to ThriveMarket.com/Hyman today to receive 30% off your first order and a free gift up to $60.

Fatty15 contains pure, award-winning C15:0 in a bioavailable form. Get an exclusive 10% off a 90-day starter kit subscription. Just visit Fatty15.com and use code DRHYMAN10 to get started.

So many people suffer from chronic Lyme disease without even knowing they have it. Why? Because it can mimic over 300 different medical conditions. On this episode of “The Doctor’s Farmacy,” I revisit my conversations with Dr. Steven Phillips, Dana Parish, and Dr. Todd LePine to unravel the complexities of Lyme disease and other tick-borne illnesses. We dive into the diagnostic and treatment challenges, and explore how functional medicine can offer solutions to your suffering. 

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Full-length episodes of these interviews can be found here:

Answering Your Questions About Lyme Disease, Detoxing, And More

The Link Between Autoimmune Disease, Chronic Fatigue, And Hidden Infections

How To Recover From Chronic Lyme And Tick Diseases with Dr. Todd LePine

This episode is brought to you by Pique, AG1, and Happy Egg.

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Have you noticed the scale inching up despite believing you're following a healthy diet? In this episode, I dive into why maintaining a healthy weight can be so challenging. We'll explore how diet, hormones, and environmental factors influence weight, and why understanding body composition is crucial. Plus, I'll provide actionable strategies, from balancing blood sugar to optimizing gut health, to help you achieve and sustain a healthy weight.

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What if the key to overcoming your autoimmune disease lies in your lifestyle? In this episode of "The Doctor's Farmacy," I’m joined by Dr. Robert Rountree to examine the alarming rise of these chronic conditions. We’ll dissect the root causes and holistic solutions to stop your suffering now. Tune in to discover how personalized lifestyle changes and functional medicine can offer hope and healing.

In this episode, we discuss:

• How toxins like heavy metals can trigger autoimmune responses and affect overall health
• The role of dietary triggers and food sensitivities in the development and management of autoimmune diseases
• The importance of gut health in autoimmune conditions, including the impact of microbial imbalances and the gut microbiome
• The significant role of stress and sleep in modulating immune responses and managing autoimmune conditions
• The importance of individualized lifestyle changes, including diet, stress management, and exercise, in managing and potentially reversing autoimmune conditions

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This episode is brought to you by Rupa Health, Butcher Box, BIOptimizers, and Sunlighten. 

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We all know mitochondria is “the powerhouse of the cell” thanks to middle school science class, but when does that mean when we’re talking about our overall health and longevity? In this episode, I dive into the fascinating world of mitochondrial health with Dr. Steven Gundry and Dr. Andrew Salzman. We discuss how optimizing mitochondrial function through diet, exercise, and light exposure can dramatically improve your health and energy levels. Plus, we explore the impacts of chronic inflammation, leaky gut, and environmental toxins on our mitochondria and overall well-being.

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4 Non-Negotiables To Boost Energy And Optimize Your Mitochondria

Sick And Tired Of Being Sick And Tired? How To Reclaim Your Energy

How Supplementing With NMN Can Increase NAD levels, Energy, Reduce Inflammation, And Improve Insulin Resistance

After a distinguished surgical career as a professor and chairman of cardiothoracic surgery at Loma Linda University, Dr. Gundry changed his focus to curing modern diseases via dietary changes. He is the author of New York Times bestseller The Plant Paradox, The Plant Paradox Cookbook, The Plant Paradox Quick & Easy,andThe Longevity Paradox,along with national bestsellersThe Plant Paradox Family Cookbook, The Energy Paradox,Dr. Gundry’s DietEvolution,andUnlocking the Keto Code, and has had more than three hundred articles published in peer-reviewed journals on using diet and supplements to eliminate heart disease, diabetes, autoimmune disease, and multiple other diseases. He just released his latest book,Gut Check: Unleash the Power of Your Microbiome to Reverse Disease and Transform Your Mental, Physical, and Emotional Health.

Dr. Andrew Salzman is a physician, inventor, professor, and biomedical entrepreneur. Dr. Salzman received his medical degree from Harvard University and has spent decades in drug discovery and development, raising over $165M in NIH grants for research. In addition to 50 patents, Dr. Salzman is credited with a breakthrough discovery in cellular DNA repair, which led to the world’s first clinical application for successfully treating breast cancer caused by mutations in BRCA1 and BRCA2 genes. Millions of patients are benefiting from discoveries by Dr. Salzman in areas including mitochondrial health, gastrointestinal microbiota, damage caused by inflammation and oxidative stress to human cells and DNA, autoimmune disease, and cancer.

This episode is brought to you by Pendulum, Cozy Earth, and SleepMe.

Pendulum is offering listeners 20% off their first membership order at pendulumlife.com/farmacy. Discount applied at checkout.

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Customize your sleep with ChiliPad. Visit sleep.me/DRHYMAN and save up to $315 with code DRHYMAN.

Did you know that what you eat could significantly affect your ability to have children? In this episode, I’m demystifying the vital connection between fertility and nutrition, discussing how diet influences DNA, cellular health, and reproductive wellness. Tune in to discover how avoiding ultra-processed foods and incorporating key nutrients can improve your fertility outcomes and overall health.

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This episode is brought to you by Rupa University and Happy Egg.

Rupa University is hosting FREE classes and bootcamps for healthcare providers who want to learn more about Functional Medicine testing. Sign up at RupaUniversity.com.

Shopping for better eggs shouldn’t be confusing. Look for the yellow carton at your local grocery store or visit happyegg.com/farmacy to find Happy Egg near you.

Dementia and Alzheimer’s are rising at an alarming rate, affecting millions worldwide and costing trillions in healthcare. In this episode of “The Doctor’s Farmacy,” I sit down with Dr. Heather Sandison to explore groundbreaking personalized treatment approaches that offer hope in reversing cognitive decline. Learn more about the impact of lifestyle interventions, the role of environmental toxins, and the power of holistic methods compared to conventional treatments.

In this episode, we discuss:

• The rising prevalence of Dementia and Alzheimer's
• The importance of personalized treatment plans for cognitive decline
• The critical role of lifestyle interventions, including diet, exercise, sleep, and stress management, in reversing cognitive decline.
• How toxins, such as heavy metals and mold exposure, contribute to cognitive decline
• The advancements in diagnostics, including more accurate and early detection methods for dementia and Alzheimer’s
• How cognitive decline and dementia can be reversed through a multifaceted approach

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This episode is brought to you by Rupa Health, BIOptimizers, LMNT, Cymbiotika.

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Get Magnesium Breakthrough for FREE. Just go to magbreakthrough.com/hymanfree and get your FREE bottle today.

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Upgrade your supplement routine with Cymbiotika. Get 20% off with free shipping on all orders. Head to Cymbiotika.com and use code HYMAN.

Testosterone levels in men have dropped significantly over the past few decades and in this episode of "The Doctor’s Farmacy," we’ll uncover some of the reasons why. Dr. George Papanicolaou joins me to discuss the critical role testosterone plays in metabolic health and overall well-being. We dive into how low testosterone levels can impact everything from muscle mass to blood sugar control, and discuss the best methods for measuring and optimizing hormone levels. 

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Full-length episodes of these interviews can be found here:

Are Your Hormones Out Of Balance? | Know Your Numbers

Male Menopause, Low Libido and Testosterone Replacement

Fertility in Crisis: Exploring the Toxic Threats to Fertility and the Rise in Infertility

This episode is brought to you by Mitopure, Butcher Box, Purity Coffee, and Armra.

Support essential mitochondrial health and save 10% on Mitopure. Visit TimelineNutrition.com/Drhyman and use code DRHYMAN10.

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I always say I want to live to be 120 years old, but feeling strong and healthy as I age is even more important to me. In this episode of “The Doctor’s Farmacy,” I delve into the intricate relationship between inflammation and aging, emphasizing the difference between lifespan and health span. I’m breaking down everything you need to know about the gut microbiome, inflammatory triggers, and effective strategies to reduce inflammation. Plus, I’ll share some practical tips on optimizing your diet and supplements to support your body's natural detoxification processes.

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This episode is brought to you by AG1 and Happy Egg.

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Our current food system is a national emergency. It’s intricately designed to confuse and mislead consumers, making healthy choices difficult and contributing to America’s chronic disease epidemic. In this episode, I sit down with Senator Cory Booker to delve into the systemic issues impacting our diet, food labeling, and the power of policy change. 

In this episode, we discuss:

• How food packaging is designed to confuse or mislead consumers
• The link between the food system, chronic illness, and the unintended consequences of food policies that increase disease and healthcare costs.
• The harmful effects of ultra-processed foods
• The negative impact of industrial farming practices on the environment, soil health, and the nutritional quality of food
• The importance of personal health advocacy and broader public health initiatives to transform the food system, improve health outcomes, and reduce healthcare costs

Uncover the truth behind our food politics and discover how informed choices can lead to a healthier future. This conversation was hosted by Sixth and I in Washington, DC.

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This episode is brought to you by Rupa Health, Cozy Earth, Cymbiotika, and Purity Coffee.

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Millions of women experience hormonal imbalances at some point in their lives, but did you know suffering isn’t your only option? In this episode of “The Doctor’s Farmacy,” I look back on conversations with Dr. Mindy Pelz and Dr. Elizabeth Boham where we explore the complexities of hormone health. From the benefits of bioidentical hormones versus synthetic ones to the impact of diet, exercise, and stress management on hormone balance, learn how functional medicine tailors personalized treatments to enhance your overall well-being.

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This episode is brought to you by Mitopure, Happy Egg, and Cymbiotika.

Support essential mitochondrial health and save 10% on Mitopure. Visit TimelineNutrition.com/Drhyman and use code DRHYMAN10.

Shopping for better eggs shouldn’t be confusing. Look for the yellow carton at your local grocery store or visit happyegg.com/farmacy to find Happy Egg near you.

Upgrade your supplement routine with Cymbiotika. Get 20% off with free shipping on all orders. Head to Cymbiotika.com and use code HYMAN.

The perfect diet isn't always enough – sometimes we need a little help from supplements to feel our very best. On today’s episode of “The Doctor’s Farmacy,” I’m giving you the ultimate supplement stack to complement your wellness routine so you can live better. We’ll cover the basics from multivitamins to probiotics and discuss why personalized testing is key to getting it right. Let’s explore how to effectively use supplements to bridge the nutritional gaps in your diet.

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This episode is brought to you by Mitopure, Fatty15, and SleepMe.

Support essential mitochondrial health and save 10% on Mitopure. Visit TimelineNutrition.com/Drhyman and use code DRHYMAN10.

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